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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol. 53, No. 3" : 13 Documents clear
Genetic and environmental factors as strong determinants of atopic allergic disease clinical manifestations in surabaya's school children Soegiarto, Gatot; Damayanti, Luki Agustina; Effendi, Chairul
Folia Medica Indonesiana Vol. 53, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

This case-control study was conducted to assess the relative role of genetic and environmental factors in determining the clinical manifestations of atopy allergy disease in school children, which is part of a large study of the prevalence of allergic diseases in school children in Surabaya. Using a simple multi-stage random sampling, 348 children from 5 elementary schools, 4 junior high schools, and 4 senior high schools in Surabaya were involved in the study. The subjects of the study along with her parents were guided to fill out the modified ISAAC questionnaire and underwent physical examination and skin prick test using 27 common allergen types found in the environment. For the analysis, 110 school children were randomly selected from the parent sample and included in the case group of 55 people (positive skin prick test against > 1 type of allergen), and the control group of 55 people (negative skin prick test). All genetic and environmental factors data were collected and analyzed. Most of the subjects had clinical manifestations of allergic rhinitis (66.36%), asthma (21.82%), food allergies (10.9%), and atopic dermatitis (6.36%). Complete models for multiple logistic regression analysis can only be performed for overall atopic disease and allergic rhinitis disease. The first birth order and exposure to home dust mites were the most significant clinical manifestations of atopy disease (OR 4.548, 95% CI: 1.813-11.410, p=0.01). Atopy status of the father was the only significant determinant factor for the manifestation of allergic rhinitis in the study subjects (OR 3.929; 95% CI: 1.143-13.052, p=0.03). Both genetic and environmental factors interacted and determined clinical manifestations of atopy allergy disease in school pupils. The father's genetic factors were more dominant than maternal genetic factors in determining the clinical manifestations of allergic rhinitis in offspring.
Glut-1 is a promising target for atp depletion on diabetic energy deficiency syndrome Purwanto, Bambang; Harjanto, Harjanto; Asnar, Elyana
Folia Medica Indonesiana Vol. 53, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Diabetes is a metabolic syndrome which characterized with insulin insensitivity, lack of GLUT-4 membrane presentation and ATP deficiency. ATP is needed for substrate phosphorylation, signalling pathways, protein translation and cellular survival. Since GLUT-1 was discovered as alternative glucose transporter on muscle membrane, some studies started to investigate it more. This study aimed to investigate GLUT-1 presentation on diabetes muscle membrane of rat model in time. Diabetes was obtained from a 50 mg/kg B.W of streptozotocin intra peritoneal injection on rat. We found that GLUT-1 presentation increased significantly in time of diabetic stages. It correlated negatively with GLUT-4 presentation and mortality. Eccentric downhill running on diabetic rat model improved GLUT-1 presentation and blood glucose level. It was promising for diabetes management therapy at the future.
Case report: arteriovenous malformation in foot. Surgical management combined with scleroting agent Rustina, Lusi; MT, Ivan Joalsen
Folia Medica Indonesiana Vol. 53, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Diagnosis and management of arteriovenous malformation (AVM) requires a multidisciplinary approach and includes the knowledge of the pathophysiology of the blood vessels. The incidence of vascular anomalies is rare, and they are mainly localized in the head or upper extremity. There are studies on AVM with dermatological manifestations. However, studies involving manifestations in foot are rare. The goal of this report is to provide diagnosis and treatment case of an 19 year-old boy with arterio-venous malformation of the foot. A 19-year-old Indonesian male presented with a chief complaint of a painful mass on his plantar medial right foot that had been present since his birth and had increased in size. Physical examination revealed a large plantar medial mass, with size ± 8 x 5 cm, slightly mobile, bluish, soft, and non-compressible. The mass was pulsatile on palpation and no bruit. The working diagnosis of this patient was AVM. MRI showed there was a punctat or nidus, granular hyperintense in the middle and pedis with a draining vein, and the mass was laying from subcutaneous and extended into muscular layer. Surgical management was performed. Excision of AVM in subcutaneous part was combined with injection of polidocanol 1% in muscular side. Tissue pathology results revealed AVM with no evidence of malignancy. Evaluation wounds after 2 days of operation: there was no bleeding, no signs of infection, pain was reduced. Four weeks after surgery, the patient slowly could bear his full weight on his foot, and the mass and local pain were totally reduced. Length of stay in hospitals was 4 days. This report described an unusual localization of an arteriovenous malformation. Arteriovenous malformation in foot is a challenging malformation that can be successfully managed with excision and sclerosing agents.

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