Multidisciplinary Journal of Akseprin Indonesia
The Multidisciplinary Journal of Akseprin Indonesia (MJAI) is a scientific journal dedicated to publishing research results, case studies, work reports and literature reviews that are interdisciplinary and multidisciplinary in nature from various major disciplines. The journal aims to bridge the gap between sciences, promote collaboration, and present comprehensive solutions to complex challenges. The scope of MJAI includes studies from the main groups of sciences which, including: Engineering ,Physical and Chemical Science : Engineering and Technology, Material Science, Statistics, Chemical Engineering, Chemistry, Computer Science, Information Technology, Earth and Planetary Science, Energy, Mathematics, Physics and Astronomy, Mathematics Life Sciences : Agricultural, Biological Sciences, Biotechnology, Arachnology, Biodiversity and Conservation, Entomology, Limnology, Ichthyology, Malacology, Immunology and Microbiology, Neuroscience, Biochemistry, Genetics, Molecular Biology, Environmental Science, Ecology, Marine Biology. Health & Medical Science : Medicine and Dentistry, Nursing, Health Professions, Pharmacology, Toxicology, Pharmaceutical Science, Veterinary Science, Veterinary Medicine, Health Care, Medical Education. Social Science and Humanities: Arts and Humanities, Business Management, Hotel Management, Management, Economics, Law, Finance, Psychology, Political Science Tourism, Accounting, Decision Science, Education, , Physical Education, English Literature, Social Work and History., Sociology, Corporate Governance.
Articles
33 Documents
<![CDATA[Ethosomes serve as a non-invasive drug delivery system capable of penetrating the skin, merging with cell membrane lipids, and releasing pharmaceuticals ]]>
<![CDATA[Bhavana Radhika Hemanth]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[The skin is one of the largest and most accessible organs in the human body, and its application as a pathway for drug delivery presents several advantages compared to conventional drug delivery systems. These benefits encompass reduced variability in plasma medication concentrations, prevention of gastrointestinal complications and first-pass metabolism, along with enhanced patient adherence. Transdermal drug delivery systems (TDDS) are characterised as self-contained, discrete dosage forms that, upon application to undamaged skin, administer medications at a controlled rate to the systemic circulation. Ethosomes are innovative lipid carriers consisting of ethanol, phospholipids, and water. These ethosomes are engineered as a non-invasive drug delivery method capable of penetrating the skin, merging with cell membrane lipids, and releasing the drug. Ethosomes can be prepared by either thermal or non-thermal processes. Evaluation criteria for ethosomes encompass dimensions, morphology, drug concentration, and zeta potential. Ethosomes have been effectively assessed for the administration of multiple pharmaceuticals, including cyclosporine, insulin, and salbutamol. Ethosomes possess significant potential as a crucial medication delivery mechanism in the future]]>
<![CDATA[To evaluate the prevalence of digital burnout among medical science students and correlate the levels of digital burnout with other demographic variables ]]>
<![CDATA[Nisha Shainy Daud]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[Background: Frequent use and exposure to digital devices in both academic and personal settings predisposes university students to digital burnout. Objective: To evaluate the incidence of digital burnout among medical science students and to associate the levels of digital burnout with diverse demographic characteristics. Methods: A descriptive cross-sectional study was done using convenient sampling among 300 students (86.3% male, 13.7% female) across various programmes and academic levels. The instruments employed for data collection were Tool 1 - Demographic Data and Tool 2 - Digital Burnout Scale (DBS). Findings: The findings indicated that 75% of the students experienced moderate to mild burnout. In general, and across all subcategories, average ratings reflect moderate levels of burnout. A notable disparity in digital burnout was identified among age groups (F=4.62, p=0.011), with individuals aged 24 and above exhibiting the highest levels of burnout relative to their younger peers. A statistically significant difference was observed in digital burnout scores among groups categorised by online duration, specifically beyond 6 hours (F = 4.52; p = 0.007). The study reveals that students experience moderate burnout, correlated with age and duration of gadget usage. Conclusion: Specific strategies are necessary to mitigate digital burnout, particularly among seniors and individuals who engage extensively with online platforms. Institutions must thoroughly investigate the implementation of programs to foster better digital habits and offer resources that enhance students' well-being in progressive digital academic settings]]>
<![CDATA[Assessment of Saponification, Acid, Peroxide, and Iodine Values by Physicochemical Analysis of Reused Cooking Oil ]]>
<![CDATA[Lie huan zang]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[This study examines the deterioration of frying oils utilised in local food enterprises by analysing essential quality indicators. Oil samples, obtained after extended frying of typical food items like samosas, Manchurian, chicken, medu vada, jalebi, and momos for durations of 8 to 9 hours, were analysed. Palm and vegetable oils were evaluated for acid value, saponification value, peroxide value, and iodine value utilising standard titrimetric methods. Acid-base titration techniques were employed to determine acid, peroxide, and saponification levels, whereas iodometric titration was utilised for assessing iodine value. The comparative analysis underscores the chemical alterations in reused oils, stressing the importance of consistent monitoring to guarantee safety and appropriateness for ongoing usage in food preparation]]>
<![CDATA[Pharmaceutical Industry Driven by Artificial Intelligence and Machine Learning ]]>
<![CDATA[Sandha Udhan Baorhide]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[Artificial Intelligence (AI) and Machine Learning (ML) are transforming the pharmaceutical industry at all phases—drug research, development, regulatory compliance, quality assurance, and post-marketing monitoring. These technologies enhance data processing, precision, and timeliness through the utilisation of intricate algorithms and extensive healthcare datasets. Artificial intelligence aids in drug target identification, drug design, toxicity prediction, and pharmacokinetics modelling, while also enhancing regulatory processes and pharmacovigilance. Despite its advantages, difficulties persist, including data privacy, algorithmic bias, explainability, and accountability. Regulatory frameworks and ethical considerations must evolve to ensure the safe and equitable application of AI in pharmaceuticals. This article examines the current applications, benefits, hazards, and future potential of AI and ML in revolutionising medication development and healthcare outcomes.]]>
<![CDATA[A Comparative Analysis of the Efficacy of Mulligan Bent Leg Raising Versus Slump Stretching Combined with SWD in Mechanical Low Back Pain ]]>
<![CDATA[Okkagani Berranghi Obuun]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[The problem statement: Low back pain (LBP) is the most prevalent, self-reported form of musculoskeletal pain, frequently recurrent, and carries significant socio-economic implications. Approximately eighty percent of low back pain is attributed to "mechanical back pain," resulting from muscle strain or ligament tear in the back. The muscular strain and ligament sprain result from abrupt, unfamiliar exercises and incorrect posture. Methodology: The participants were recruited through Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, Pondicherry-605 102. The objective of the study was to evaluate the efficacy of Mulligan Bent Leg Raising (MBLR) compared to Slump Stretching combined with SWD in alleviating pain and enhancing Straight Leg Raise (SLR) in cases with mechanical low back pain. Outcomes: The statistical analysis derived from the unpaired t-test indicates that the post-test values for range of motion and pain in Group A and Group B are 5.39 (p < 0.001) and 5.43 (p < 0.001), respectively. The statistical study revealed a considerable difference between Group A and Group B, with Group A demonstrating more effectiveness. The study concluded that the Mulligan bent leg raise, in conjunction with SWD, was beneficial in treating mechanical low back pain in college students]]>
<![CDATA[Impact of Resistance Training on Functional Capacity and Muscle Performance in Postmenopausal Women ]]>
<![CDATA[Subashini Kirthiga Suhara]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 2 (2025): May-August ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[The objective is to investigate the impact of 12 weeks of high-speed resistance training (RT) compared to low-speed RT on muscle strength, measured by one repetition maximum leg press (1RMLP) and bench press (1RMBP), as well as dominant (HGd) and non-dominant maximum isometric handgrip strength, power, ball throwing (BT) ability, functional performance assessed through the 8-foot up-and-go test (UG) and sit-to-stand test (STS), and perceived quality of life in older women. Methods: Ninety elderly women were categorized into a high-speed resistance training group [EG, n = 30], a low-speed resistance training group [SG, n = 30], and a control group [CG, n = 30]. The SG and EG participated in an analogous 12-week resistance training program [3 sets of 10 repetitions at 40–75% of the one-repetition maximum (1 < RM) and BT], employing slow, controlled (3 seconds) concentric muscle actions for the SG and rapid, explosive (< 1 second) concentric muscle actions for the EG (20% reduced workload per exercise without BT). Results: The dependent variable exhibited enhancement in both RT groups throughout the 12-week training duration in clinically significant measures ranging from small to large; however, a notable difference was observed between the EG and SG regarding performance alterations in BT and UG (28% vs 23%, 21% vs 13%, p<0.01, respectively). No significant alterations were seen for the CG. Conclusion: Although a high-speed resistance training program yields greater enhancements in muscular power and functional task performance, both low-speed and high-speed resistance training therapies effectively increase functional capacity, muscle performance, and quality of life in older women]]>
<![CDATA[The Influence of Animal Phobia on Post-Traumatic Stress Disorder (PTSD) ]]>
<![CDATA[Ngamcha Roensukphon]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 2 (2025): May-August ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[The apprehension over animals in urban settings has emerged as a significant concern, particularly in highly populated regions such as Bangkok. With the expansion of urbanization, interactions between humans and wildlife have increased, frequently eliciting extreme fear responses that may lead to mental health issues. This study seeks to investigate the correlation between animal phobia and symptoms of Post-Traumatic Stress Disorder (PTSD), along with its effects on daily activities among inhabitants of Bangkok. We employed a standardized questionnaire to gather responses from 360 participants, assessing the impact of PTSD on everyday activities in relation to fear of animals. Our findings indicate that interactions with animals may lead to psychological anguish, with women possibly being more impacted. A plausible explanation is that elevated estrogen levels in women may heighten sensitivity to stress and emotional recollection, while testosterone in men may stabilize stress responses. This underscores the necessity of comprehending human-animal interactions in urban environments, which could guide mental health support and associated policies. These findings necessitate the examination of gender and hormonal variations in comprehending stress reactions and psychological health during animal interactions to enhance mental well-being]]>
<![CDATA[Impact of Chemotherapy on Protein Levels in Cancer Patients Undergoing Treatment ]]>
<![CDATA[Thakre Pratima]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 2 (2025): May-August ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[Cancer staging is a critical component of cancer management and directly influences the patient's treatment approach. Numerous protein tumor indicators assist in the diagnosis and prognosis of cancer patients. The objective of this study is to assess the total protein levels in serum samples from chosen cancer patients and to identify any correlations with various stages of the disease. Materials and Methods: Total proteins were quantified using the IR-VS spectroscopy approach and compared among various patients. Outcome: The spectrophotometric examination of the obtained serum samples indicated that chemotherapy-induced total protein loss correlates with the dysregulation of serum proteins and electrolytes. Total protein serves as a crucial indicator for assessing tumor stage in cancer patients; hence, it functions as a prognostic marker as well. It is a straightforward, non-invasive, and economical analytical approach]]>
<![CDATA[CRISPR Chronicles: Advancing Gene Editing in Cardiovascular Treatment ]]>
<![CDATA[Sahlan Abdullah Rohim]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 2 (2025): May-August ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[CRISPR-Cas technologies have transformed gene editing, providing accurate and effective genome alterations with extensive implications in biological research and treatment strategies. This technology has eclipsed conventional techniques, including zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs), owing to its simplicity, cost-efficiency, and superior precision. In cardiovascular disease (CVD) research, CRISPR has been essential in creating accurate disease models, pinpointing genetic risk factors, and formulating possible therapeutic approaches. Genome editing has facilitated the rectification of monogenic mutations associated with inherited cardiomyopathies and arrhythmias while also addressing metabolic risk factors like PCSK9 to mitigate atherosclerosis. Innovations including base editing, prime editing, and RNA editing have augmented CRISPR's accuracy, reducing off-target effects and enhancing therapeutic relevance. Delivery modalities, encompassing adeno-associated viral (AAV) vectors and nanoparticle-based approaches, have been refined to improve efficacy and safety. Notwithstanding these advancements, difficulties, including inadvertent genetic alterations, immunological reactions, and ethical dilemmas surrounding germline editing, remain. The effective clinical implementation of CRISPR therapeutics necessitates additional refinement, stringent validation, and regulatory supervision to guarantee safety and efficacy. Ongoing research indicates that CRISPR-based genome editing possesses significant advantages for improving cardiovascular treatment. Advancements in delivery methods, enhanced precision in gene editing, and ethical considerations will be pivotal in the incorporation of CRISPR into clinical practice. Through ongoing advancement, CRISPR possesses the capacity to emerge as a revolutionary therapeutic instrument, providing accurate and enduring remedies for cardiovascular diseases and many genetic problems]]>
<![CDATA[Cystic Hygroma Is Particularly Concerning When Identified During The First Trimester ]]>
<![CDATA[Hu Shi Xuan]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 2 (2025): May-August ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
<![CDATA[Cystic hygroma is a congenital condition marked by benign cysts resulting from lymphatic system abnormalities, comprising approximately 6% of all benign lesions in infancy or early childhood. This case report details a 24-year-old G3A1E1 woman with a history of induced abortion and ectopic pregnancy, diagnosed with fetal cystic hygroma at 12 weeks and 4 days of gestation. Obstetric ultrasonography identified a single, viable, intrauterine fetus exhibiting a distinct thin-walled cystic lesion with many internal septations located in the occipital region, spreading to the thorax, alongside a nuchal translucency measurement of 9 mm. The patient received counseling for medical termination of pregnancy and then underwent an induced abortion. Cystic hygroma, particularly when identified in the first trimester, is frequently linked to chromosomal anomalies and adverse prognoses. Research indicates that the overall survival rate for embryonic cystic hygroma is 10%, and the prognosis remains uncertain until the fetus reaches 26 weeks of gestation. Early identification of cystic hygroma using prenatal ultrasonography facilitates prompt intervention and informed decision-making. This example illustrates the importance of early prenatal screening and detection of fetal defects, as well as the necessity for a multidisciplinary approach in addressing intricate obstetric cases. Additional genetic counseling and testing could be advantageous for the patient in strategizing future pregnancies]]>
