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International Journal of Biomedical Science and Travel Medicine
Published by Universitas Warmadewa
ISSN : 30477441     EISSN : 30477433     DOI : https://doi.org/10.22225/ijbstm
Core Subject : Health,
Medicine & Pharmacology Public Health
International Journal of Biomedical Science and Travel Medicine is published twice (March and September) a year. The objective is to promote articles on biology and medicine. International Journal of Biomedical Science and Travel Medicine publishes original research work related to biological and medicine. The journal publishes Original articles, Short Reports, Case Reports, and Review articles. All articles published in International Journal of Biomedical Science and Travel Medicine (IJBSTM) are peer-reviewed and published online for immediate access and citation. International Journal of Biomedical Science and Travel Medicine (IJBSTM) publishes the Original clinical and experimental research studies, Review articles, Case reports on topics but not limited to: Biocemistry, Genetics and molecular biology, Medicine, Environmental health, Tropical diseases, Diseases in tropics, Global health, Pharmacological sciences, Biomedical sciences, Public health, Infection, Epidemiology and clinical epidemiology, Molecular biology, Microbiology, Travel Medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "vol. 2 no. 2 (2025)" : 5 Documents clear
Characteristics of Fractures among International Travellers in Bali Ketut Ngurah Bagaskara M; Sri Ratna Dewi
International Journal of Biomedical Science and Travel Medicine Vol. 2 No. 2 (2025)
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.2.2.2025.35-40

Abstract

An increase in the number of foreign tourists in Bali will likely lead to a rise in musculoskeletal traumas, particularly fractures. The characteristics of fractures vary in terms of aetiology, age, and location, as well as the mechanism of injury (MOI), which, in turn, have different forms of treatment. This study aimed to determine fracture characteristics based on demographics, the affected bone fractures, the relationship between the bone and surrounding tissue, and fracture configuration. The research method used is a descriptive observational approach, drawing from patient notes or medical records of patients undergoing inpatient or outpatient treatment between January 2022 and December 2023. The sampling technique used in this research is consecutive sampling. The minimum number of samples required for this research is 96. The data in this research were analysed descriptively and presented in the form of narratives, tables, graphs, or images. The research results showed that respondents who experienced fractures were primarily Russian citizens, accounting for 25% of the total. Most respondents experienced closed fractures, totalling 90. The most common fault lines were complete fractures, with 92 respondents, and experienced transverse fracture characteristics, with 55 respondents. The highest number of fractures occurred in the Metatarsal V, with 20 respondents experiencing single-site fractures.
Biomolecular Mechanism Of Hyperbaric Oxygen Therapy As An Alternative Treatment In Autism Spectrum Disorder Finnesia Arisca
International Journal of Biomedical Science and Travel Medicine Vol. 2 No. 2 (2025)
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.2.2.2025.41-45

Abstract

Introduction Many alternatives have appeared in the recent technology days for Autism Spectrum Disorder (ASD), many which may have higher risks and harder compliance especially for children. Hyperbaric oxygen therapy (HBOT) has been in a lot of talks as an alternative treatment for ASD lately and showed improvements in the recent cases. This paper aims to elaborate about biomolecular mechanism involved and how it affect the symptoms of ASD. Methods This research was conducted using the electronic databases Pubmed, GoogleScholar, EBSCO, ScienceDirect, Ovid, Science, Springer, Scopus, Cochrane Database, Web of Science and Wiley Online Library for articles published between January 2020 and May 2025. Only peer-reviewed articles published in English were included. Results HBOT works by reducing tissue hypoxia, increasing mitochondrial function, restoring impaired blood circulation, anti-inflammatory effects, and many more. These effects help relieve psychological and behavioral symptoms of ASD, especially the alleviating effects on mitochondrial biochemical dysfunction. Conclusion Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by difficulties in communication, social interaction, and repetitive behaviors. While its exact cause remains unclear, ASD cases in Indonesia are rising. Hyperbaric Oxygen Therapy (HBOT) shows potential in easing symptoms, particularly related to mitochondrial dysfunction, but its safety and efficacy need further study.
Prevalence of qacE AND qacE[delta]1 resistance genes in pseudomonas species isolates from hospitals in Benin City, Nigeria Felix. A. Okunrobo; Helen. O Ogefere; Richard Omoregie
International Journal of Biomedical Science and Travel Medicine Vol. 2 No. 2 (2025)
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.2.2.2025.52-59

Abstract

Background: The multi-drug efflux pump systems play a significant role in the mechanism of resistance to biocides in Pseudomonas species. This bacterium has been shown to harbor multi-drug transporter efflux systems genes involving QacE and QacE[delta]l, as do other gram negative bacteria. In Nigeria, the use of antimicrobial agents is unregulated, particularly the use of biocidal formulations both in health care facilities and for domestic purposes. Due to paucity of data on the distribution of qac genes in the health-care environment in Nigeria, this study aimed to determine the distribution of qacE and qacE[delta]1 genes among Pseudomonads–both aeruginosa and non-aeruginosa isolates, from clinical and environmental sources within hospitals in Benin City. Method: A total of 1200 specimens consisting of 500 clinical (wound, urine, ear swabs, high vaginal and endo-cervical swabs, eye swabs, aspirates, catheter tips, sputum and throat swabs) and 700 environmental (sinks, floors and bench tops) were used for this study. All specimens were processed to recover Pseudomonads using cetrimide agar. The isolates were identified with biochemical tests and 16S rRNA. The presence of qacE and qacE[delta]1 genes was detected by PCR (polymerase chain reaction). Result: Pseudomonas aeruginosa and non-aeruginosa isolates were recovered mostly from sinks and wounds. The prevalence of qacE and qacE[delta]1 genes did not differ significantly (p>0.05) between P. aeruginosa and their non-aeruginosa counterparts in both clinical and environmental isolates. In conclusion, we highlight the prevalence of qacE and qacE[delta]1 resistance genes in varying proportions among clinical and environmental pseudomonas species isolates in hospitals in Benin city, Nigeria  
Phagocytic Receptors Mediate Survival and Locomotor Resilience of Ethanol-Exposed Drosophila Julia Citra Prastika; Sri Wahyuni M; Reski Amalia Rosa; Nadila Pratiwi Latada; Mukarram Mudjahid; Risfah Yulianty; Firzan Nainu
International Journal of Biomedical Science and Travel Medicine Vol. 2 No. 2 (2025)
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.2.2.2025.46-51

Abstract

Background Ethanol is a widely studied toxicant known to induce oxidative stress and cellular damage across species. While phagocytic clearance is essential for maintaining tissue homeostasis, its role in protecting against ethanol-induced toxicity remains poorly understood. This study aims to elucidate the role of phagocytic receptors in modulating the organism’s response to ethanol-induced toxicity using Drosophila melanogaster. Methods To assess the functional significance of phagocytic receptors, we utilized behavioral locomotor assay and survival analysis on both wild-type and mutants deficient in the phagocytic receptors Draper and Integrin-[beta]v of Drosophila which are homologous to mammalian MEGF10 and integrins, respectively. Flies were exposed to the various concentration of ethanol, and their climbing ability and survival responses were compared across genotypes. Results Our results revealed that mutants lacking Draper and/or Integrin-[beta]v showed a significant reduction in locomotor activity (p < 0.05 to p < 0.0001) and an approximately two-fold decrease in survival time under ethanol exposure compared with wild-type flies. These findings indicate that impaired phagocytic clearance may exacerbate ethanol toxicity. Conclusion In summary, this study demonstrates that phagocytic receptors play a critical protective role against ethanol toxicity in D. melanogaster. The data suggest the interconnected roles of oxidative stress, apoptosis, and phagocytosis in maintaining tissue homeostasis, validating Drosophila as a robust model for investigating the effect of toxicant on the phenotypic features of metazoan species.
Screening and Risk Factor Assessment of Cataract and Glaucoma in Hypertensive and Diabetic Populations along the Surabaya Coast Irma Andriani Pasaribu; Aditya Wira Buana; Prawesty Diah Utami
International Journal of Biomedical Science and Travel Medicine Vol. 2 No. 2 (2025)
Publisher : Publication Department, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/ijbstm.2.2.2025.60-64

Abstract

Background: The coexistence of cataract, glaucoma, diabetes mellitus, and hypertension imposes a substantial ocular health burden in aging populations, especially in coastal communities exposed to ultraviolet radiation. Methods: This observational-analytical study evaluated the influence of hypertension and diabetes mellitus on the incidence of cataract and glaucoma among residents of Kedung Cowek, Surabaya (April 2025). Direct clinical examinations, demographic and medical histories, and ocular assessments were performed on all eligible patients presenting with blurred vision and documented hypertension or diabetes (total sampling). Results: Among 12 hypertensive patients along the Surabaya Coast, 8 (66.7%) had ocular abnormalities. Cataract was the most common finding (5 cases, 41.7%), followed by glaucoma (3 cases, 25%). Pterygium occurred in 4 cases (33.3%), likely linked to high UV exposure. Conclusion: Diabetes, and hypertension appears to accelerate cataract and glaucoma development in this coastal population. Oxidative stress from combined metabolic and environmental factors may overwhelm ocular defenses, increasing vision-related risk.

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