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All Journal Jurnal Kedokteran dan Kesehatan Vision Science and Eye Health Journal
Pasaribu, Irma Andriani
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Medicine & Pharmacology Neuroscience Nursing Public Health

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Correlation Between Sleep Duration and Visual Acuity: A Single Center Study Arianto, Huda Fajar; Pasaribu, Irma Andriani; Artati, Indira Retno
Vision Science and Eye Health Journal Vol. 3 No. 1 (2023): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v3i1.2023.1-7

Abstract

Introduction: Students, especially at the senior high school level, are increasingly required to be able to develop according to predetermined standards. When the duration of learning increases, unconsciously, the duration of using the eyes also increases while the sleep duration decreases. Purpose: This study aims to analyze the correlation between short duration of sleep and decreased visual acuity among senior high school students. Methods: A cross-sectional study design was conducted, in which the students filled out questionnaires and underwent visual examination. The population was all final-year students at one of Sidoarjo Senior High School in East Java, with the age range of 16-18 years. Two variables involved in this study were sleep duration and visual acuity of the left and right eye. The data will be analyzed using Spearman Rho correlation analysis to determine the cause and effect of the two variables studied. Results: The sample according to the gender was 45.5% male and 54.5% female. The sample according to the age range was 76.1% in 17 years old and 23.9 % in 18 years old. The correlation test results were 0.277 and 0.009 for the correlation coefficient and the significance value for the right eye. The results were 0.234 for the correlation coefficient and 0.028 for the significance value for the left eye. There was a significant correlation between sleep duration and the visual acuity reduction. Conclusions: This study reveals that less sleep duration of the final year students between 16-18 years old range may be associated with reduced visual acuity among students.
Khasiat Hepatoprotektor Ekstrak Brokoli pada Kadar SGOT dan Katalase Hepar Tikus yang Diinduksi Deksametason Untari, Ni Komang Sri Dewi; E.J.T., Sihning; Pasaribu, Irma Andriani
Jurnal Kedokteran dan Kesehatan Vol 22 No 1 (2026): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

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Abstract

Brokoli (Brassica oleracea var. Italica) mengandung flavonoid dan fenol tingkat tinggi, yang merupakan antioksidan alami yang kuat. Senyawa-senyawa ini dapat berfungsi sebagai hepatoprotektor, mencegah kerusakan hati yang disebabkan oleh dosis obat yang toksik. Deksametason, bila diberikan dalam dosis tinggi, dapat menyebabkan cedera hati. Aktivitas enzim hati seperti SGOT dan katalase dapat bertindak sebagai biomarker untuk kerusakan hati. Penelitian ini bertujuan untuk menilai efek hepatoprotektif ekstrak brokoli dengan menganalisis aktivitas enzim hati pada tikus putih jantan (Rattus norvegicus) yang terpapar deksametason dosis tinggi. Penelitian ini mengikuti Desain Eksperimental dengan kelompok kontrol pasca-uji saja. Sebanyak 30 tikus Wistar jantan yang sehat, berusia 9-12 minggu dan berat 150-200g, secara acak dimasukkan ke dalam tiga kelompok. Kelompok kontrol negatif tidak menerima pengobatan, sedangkan kelompok kontrol positif diberi deksametason dari hari ke-15 hingga hari ke-24. Kelompok perlakuan menerima ekstrak brokoli dari hari ke-8 hingga hari ke-14, diikuti oleh deksametason dari hari ke-15 hingga hari ke-24. Temuan penelitian menunjukkan bahwa ekstrak brokoli memengaruhi kadar SGOT pada tikus yang diobati dengan deksametason dosis tinggi. Namun, tidak ada efek signifikan ekstrak brokoli terhadap kadar katalase pada tikus yang diinduksi deksametason.
Co-Authors Arianto, Huda Fajar Artati, Indira Retno E.J.T., Sihning UNTARI, NI KOMANG SRI DEWI