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Kota surabaya,
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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Immunology & microbiology Public Health
Arjuna Subject : -
Articles 12 Documents
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Search results for , issue "Vol. 28 No. 2 (2016): AGUSTUS" : 12 Documents clear
A Retrospective Study: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Yuli Wahyu Rahmawati; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.956 KB) | DOI: 10.20473/bikk.V28.2.2016.146-154

Abstract

Background: Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) is rare, but threaten the patient's life. Purpose: To evaluate management of SJS and TEN. Methods: A  retrospective study to patient with SJS and TEN in  2011-2014, data regarding the prevalent of patients, history of patients, etiology, clinical manifestation, supporting of examination, therapy, complication, mortality, follow up, and duration of treatment patients recorded from medical report. Result: Total patient with SSJ and NET were 37 patients. Most patients were female (73%) with majority age range 25-44 years (48.6%), epilepsy is the most comorbidities (27%), the main etiology the use of drug (62.1%), the highest class of drugs is analgesic drugs (38.6%), 37 patients using corticosteroid for therapy (100%), skin is the most complication (50.9%), and death rate was zero (0%). Conclusion: Management of patients with SJS and TEN gives complete recovery. Key words: Stevens-Johnson syndrome, toxic epidermal necrolysis, management.
Profile of Serum Insulin-like Growth Factor-1 Levels in Patients with Acne Vulgaris I G.A. Kencana Wulan; Afif Nurul Hidayati; Hari Sukanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.256 KB) | DOI: 10.20473/bikk.V28.2.2016.104-112

Abstract

Background: Acne vulgaris (AV) is a skin disease that is commonly found in adolescence. In addition to causing physical disorders, acne vulgaris affects the quality of life of patients that cause social disorder, psychological, and emotional. Based on the observations of the experts, AV is rarely found in non-westernized populations, indicates an underlying environmental factors including diet. Excessive sebum production has an important role in the pathogenesis of AV. One of the factors which allegedly associated with the production of sebum and diet is IGF-1 in serum. Purpose: To evaluate the levels of IGF-1 serum in patients with AV with varying degrees of severity. Methods: This study is an observational cross-sectional study in 38 AV patients aged 15-24 years at the Outpatient Clinic of Dermatovenereology Department of Dr. Soetomo Hospital Surabaya as many as 38 people. The severity of AV are grouped according to the method of Combined Acne Severity Classification (CASC). Anamnesis of diet based on the table of load and glycemic index foods. Subjects has been collected through consecutive sampling. Results: Serum IGF-1 levels in the mild AV group was 155,000 (SD±23,381) µg/ml, in the moderate AV group was 211,052 (SD±85,498) µg/ml and in severe AV group was 150,000 (SD±45,826) µg/ml. Serum IGF-1 levels in male group was higher than female, was 199,230 (SD±85,582) µg/ml and in female group was 174,000 (SD±58,238) µg/ml. Serum IGF-1 levels in the aged group of 15-20 years was 192,270 (SD±80,766) µg/ml, higher than the aged group of 21-24 years, was 169,380 (SD±46,829) µg/ml. Conclusion: The mean levels of IGF-1 in patients with moderate degrees of AV was higher than mild or severe. IGF-1 levels can vary influenced by many factors. Key words: acne vulgaris, serum IGF-1, severity degrees of acne vulgaris.

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