cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rizky Abdulah
Contact Email
r.abdulah@unpad.ac.id
Phone
-
Journal Mail Official
editorial@ijcp.or.id
Editorial Address
-
Location
Kota bandung,
Jawa barat
INDONESIA
Jurnal Farmasi Klinik Indonesia
Published by Universitas Padjadjaran
ISSN : 23375701     EISSN : 2337 5701     DOI : -
Core Subject :
Indonesian Journal of Clinical Pharmacy (IJCP) is a scientific publication on all aspect of clinical pharmacy. It published 4 times a year by Clinical Pharmacy Master Program Universitas Padjadjaran to provide a forum for clinicians, pharmacists, and other healthcare professionals to share best practice, encouraging networking and a more collaborative approach in patient care. Indonesian Journal of Clinical Pharmacy is intended to feature quality research articles in clinical pharmacy to become scientific guide in fields related to clinical pharmacy. It is a peer-reviewed journal and publishes original research articles, review articles, case reports, commentaries, and brief research communications on all aspects of Clinical Pharmacy. It is also a media for publicizing meetings and news relating to advances in Clinical Pharmacy in the regions.
Arjuna Subject : -
Articles 16 Documents
 1   2 
Search results for , issue "Vol 5, No 4 (2016)" : 16 Documents clear
Hubungan Kepatuhan Menggunakan Obat Inhaler β2-Agonis dan Kontrol Asma pada Pasien Asma Haryanti, Sri; Ikawati, Zullies; Andayani, Tri M.; Mustofa, Mustofa
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.089 KB) | DOI: 10.15416/ijcp.2016.5.4.238

Abstract

Asma tetap menjadi masalah kesehatan yang dialami banyak anak-anak dan orang dewasa di dunia. Sebagai penyakit kronis, tata laksana asma memerlukan pengobatan yang berkelanjutan. Salah satu masalah penting dalam tata laksana asma adalah kepatuhan dalam pengobatan. Kepatuhan yang rendah terhadap anti-asma yang diberikan menyebabkan meningkatnya morbiditas dan mortalitas. Penelitian ini dilakukan untuk mengkaji hubungan kepatuhan terhadap anti-asma yang diberikan dengan kontrol asma. Penelitian ini merupakan penelitian observasional menggunakan rancangan potong lintang yang dilakukan di empat rumah sakit di Daerah Istimewa Yogyakarta selama enam bulan, yaitu antara bulan Juni sampai Desember 2015. Subjek penelitian adalah pasien dengan gangguan fungsi pernafasan yang menjalani pengobatan di poliklinik penyakit dalam di rumah sakit tersebut dan memenuhi kriteria inklusi dan eksklusi serta bersedia ikut dalam penelitian dengan menandatangani surat pernyataan persetujuan. Kepatuhan diukur dengan Morisky Medication Adherence Scale (MMAS) dan kontrol asma diukur dengan Asthma Control Test (ACT). Uji korelasi Pearson digunakan untuk mengkaji hubungan antara kepatuhan dan kontrol asma. Total sebanyak 67 pasien diseleksi dan 57 diantara memenuhi kriteria inklusi dan eksklusi. Berdasarkan kepatuhannya, pasien dikelompokkan ke dalam kepatuhan sedang (31 pasien atau 54%) dan kepatuhan rendah (26 pasien atau 46%). Berdasarkan kontrol asma, pasien dikelompokkan ke dalam kontrol asma sebagian (11 pasien atau 19%) dan tidak terkontrol asma (47 pasien atau 81%). Terdapat hubungan signifikan antara kepatuhan dengan kontrol asma (r=0,303, p<0,05). Kesimpulan, kepatuhan terapi dapat meningkatkan kontrol asma.Kata kunci: Anti-asma, kepatuhan, kontrol asma, tata kelola asmaRelationship Between Compliance of Using β2-Agonist Inhaler Drugand Asthma Control on Asthma Patient Asthma remains a health problem affecting a large number of children and adult in the world. Being a chronic disease, asthma management requires continous medications. One of the most important issues in asthma management is adherence to treatment. Poor compliance with prescribed anti-asthma leads to increase in morbidity and mortality. This study was conducted to evaluate the relationship between ompliance prescribed anti-asthma and asthma control. This was an observasional study using cross-sectional design conducted in four hospitals around Province of DI Yogyakarta during six months om June until December 2015. Subjects were patients with respiratory disorders who underwent treatment in internal medicine polyclinic in the hospitals, met the inclusion and exclusion criteria and willing to participate in the study by signing the informed consent. Compliance was assesseed by Morisky Medication Adherence Scale (MMAS) and asthma control was assessed by Asthma Control Test (ACT). Pearson’s correlation test was used to evaluate the relationship between compliance and asthma control. A total of 67 patients were selected and 57 of them met the inclusion and exclusion criteria. Based on the patient’s compliance, the patients were grouped into moderate compliance (31 patients or 54%) and low compliance (26 patients or 46%). Whereas based on the asthma control, the patients were grouped into partly controlled asthma (11 patient or 19%) and uncontrolled asthma (47 patients or 81%). There is a significant relationship between compliance with asthma control (r=0303, p<0.05). Conclusion, compliance can increase asthma control.Keywords: Anti-asthma, asthma control, asthma management, compliance
Studi Penggunaan Antibiotik Berdasarkan ATC/DDD dan DU 90% di Bagian Bedah Digestif di Salah Satu Rumah Sakit di Bandung Mahmudah, Febrina; Sumiwi, Sri A.; Hartini, Sri
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.209 KB) | DOI: 10.15416/ijcp.2016.5.4.293

Abstract

  tidak tepat dapat menimbulkan berbagai masalah, di antaranya pengobatan akan lebih mahal, efek samping lebih toksik, meluasnya resistensi dan timbulnya kejadian superinfeksi yang sulit diobati. Tujuan penelitian ini adalah untuk mengetahui pola penggunaan antibiotik pada pasien bedah digestif di salah satu rumah sakit di Bandung. Data penggunaan antibiotik diperoleh dari Instalasi Rekam Medis pada Juli–Desember 2013. Data diperoleh dengan metode ATC/DDD dan DU 90%. Penelitian ini merupakan penelitian deskriptif dengan studi retrospektif yang diambil dari catatan medik untuk menilai kuantitas dan kualitas penggunaan antibiotik. Sampel diambil dengan cara simple random sampling. Hasil penelitian menunjukkan bahwa dari 208 catatan medik didapatkan total penggunaan antibiotik 17,9 DDD/100 hari rawat dan antibiotik yang masuk dalam DU 90% yaitu seftriakson (8,77 DDD/100 hari rawat), metronidazol (4,61 DDD/100 hari rawat), sefiksim (1,09 DDD/100 hari rawat), sefepim (0,85 DDD/100 hari rawat), siprofloksasin (0,73 DDD/100 hari rawat), dan meropenem (0,42 DDD/100 hari rawat). Hasil penelitian menunjukkan bahwa secara kuantitas penggunaan antibiotik yang paling banyak adalah seftriakson sebesar 8,77 DDD/100 hari rawat dan antibiotik yang masuk dalam segmen 90% yaitu seftriakson, metronidazol, sefiksim, sefepim, siprofloksasin, dan meropenem.Kata kunci: ATC, DDD, kuantitas, studi penggunaan antibiotikStudy of the Use of Antibiotics with ATC/DDD System and DU 90% in Digestive Surgery in Hospital in Bandung Abstract Antibiotics are the most widely prescribed medicines in the hospital. Improper use of antibiotics can cause various problems, such as treatment will be more expensive, more toxic side effects, and the emergence of widespread resistance superinfection events that are difficult to treat. The objective of this study was to determine quantity and pattern of antibiotic usage in hospitalized patients at one hospital in Bandung. Sample were taken by simple random sampling method. The quantity of antibiotics usage was assessed by counting the Defined Daily Dose (DDD)/100 patient days and DU 90%. Based on 208 patient medical records, it was found that total antibiotic usage was 17.9 DDD/100 patient days and antibiotics were included in the DU 90% is ceftriaxone (8.77 DDD/100 patient days), metronidazole (4.61 DDD/100 patient days), cefixime (1.09 DDD/100 patient days), cefepime (0.85 DDD/100 patient days), ciprofloxacin (0.73 DDD/100 patient days) and meropenem (0.42 DDD/100 patient days. The results showed that the use of antibiotics in quantity at most is ceftriaxone for 8.77 DDD / 100 days of hospitalization and antibiotics included in segment 90% were ceftriaxone, metronidazole, cefixime, cefepime, ciprofloxacin, and meropenem.Keywords: ATC, DDD, quantity, study of the use of antibiotics
Validasi Kuesioner Skala Kelelahan FACIT pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Rutin Sihombing, Jhonson P.; Hakim, Lukman; Andayani, Tri M.; Irijanto, Fredie
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.394 KB) | DOI: 10.15416/ijcp.2016.5.4.231

Abstract

Anemia sangat umum terjadi pada pasien penyakit ginjal kronis (PGK). Salah satu akibat dari anemia adalah terjadinya kelelahan sehingga pasien mengalami penurunan kualitas hidup. Kuesioner Skala Kelelahan Functional Assessment Chronic Illness Therapy (FACIT) adalah suatu instrumen untuk mengetahui tingkat kelelahan pasien. Di Indonesia, kuesioner Skala Kelelahan FACIT belum pernah divalidasi. Tujuan penelitian ini adalah untuk memvalidasi kuesioner Skala Kelelahan FACIT versi Indonesia sebagai salah satu instrumen pengukuran kualitas hidup pasien. Skala Kelelahan FACIT diterjemahkan kedalam bahasa Indonesia dan dibagikan kepada pasien PGK yang menjalani hemodialisis rutin di rumah sakit akademik di Yogyakarta pada periode Mei–Oktober 2015. Validitas dievaluasi dengan uji Pearson correlation dan reliabilitas dievaluasi dengan uji Cronbach alpha. Hasil uji validitas menunjukkan semua butir pertanyaan valid karena nilai r hitung lebih besar dari nilai r tabel=0,279 dan reliabel karena r11=0,646>0,6 yang menunjukkan bahwa instrumen kuesioner reliabel. Kesimpulannya adalah kuesioner Skala Kelelahan FACIT versi Indonesia merupakan suatu pengukuran yang ringkas dan valid untuk memonitor gejala anemia dan efeknya pada pasien penyakit ginjal kronis.Kata kunci: FACIT, hemodialisis, penyakit ginjal kronis, validasi Validation of Indonesian Version of FACIT Fatigue Scale Questionnaire in Chronic Kidney Disease (CKD) Patients with Routine Hemodialysis Anemia is common in Chronic Kidney Disease (CKD). One of anemia consequences is fatigue which can lead to decrease in quality of life. Functional Assessment Chronic Illness Therapy (FACIT) Fatigue Scale is an instrument to measure patient’s score of fatigue. This questionnaire is not validated yet in Indonesia. The aim of this study is to validate Indonesian version of Functional Assessment Chronic Illness Therapy (FACIT) Fatigue Scale as an instrument for patient’s quality of life. FACIT Fatigue Scale was translated into Indonesian and administrated to CKD patients with routine homodialysis in an academic hospital in Yogyakarta on May until October 2015. The validity was evaluated by Pearson correlation test and the reliability was evaluated by Cronbach’s alpha test. Validity test showed that all of the questions were valid because r count was bigger than r table=0,279 and reliable because r11=0,646>0,6. In conclusion, Indonesian version of FACIT Fatigue Scale was a brief and valid to monitor important symptom and its effect on CKD patients with routine hemodialysis.Keywords: Chronic kidney disease, FACIT, hemodialysis, validity
Perbedaan Fungsi Ginjal, Hati dan Darah pada Pasien Kanker Serviks dengan Kemoterapi Bleomisin, Oncovin®, Mitomisin dan Karboplatin (Studi Kasus di RSUP Sanglah Denpasar Tahun 2015) Noviyani, Rini; Budiana, I Nyoman G.; Indrayathi, Putu A.; Niruri, Rasmaya; Tunas, I Ketut
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (552.043 KB) | DOI: 10.15416/ijcp.2016.5.4.269

Abstract

  Regimen Bleomisin Oncovin® Mitomisin-Karboplatin (BOM-Karboplatin) sebagai kemoterapi tidak terlepas dari efek samping yang ditimbulkan yaitu toksisitas pada organ tubuh diantaranya adalah ginjal, hati, dan darah, dimana terjadinya toksikitas pada organ ginjal dapat diindikatorkan dengan parameter Serum Kreatinin dan Blood Urea Nitrogen (BUN). Terjadinya toksisitas pada organ hati dapat diukur dengan parameter SGOT dan SGPT serta toksisitas pada fungsi darah diindikatorkan dengan nilai hemoglobin, trombosit, leukosit. Belum terdapat data mengenai efek toksik dari kemoterapi BOM-Karboplatin pada pasien kanker serviks sel skuamosa stadium IIB–IIIB di RSUP Sanglah Denpasar, sehingga penelitian ini dilakukan melalui pemantauan terhadap fungsi ginjal, hati dan darah. Penelitian ini merupakan studi kasus observasional terhadap sembilan pasien yang diikuti selama tiga seri kemoterapi dari bulan Februari hingga Agustus 2015. Data serum kreatinin, BUN, SGOT, SGPT, hemoglobin, trombosit, dan leukosit yang diperoleh dianalisis menggunakan uji t berpasangan untuk data yang terdistribusi normal dan uji Wilcoxon untuk data yang tidak terdistribusi normal dengan tingkat kepercayaan 95% dan dikatakan berbeda bermakna bila p<0,05. Hasil studi kasus ini menunjukkan nilai serum kreatinin (p=0,530), BUN (p=0,553), SGOT (p=0,162), SGPT (p=0,054), Hemoglobin (p=0,034), Trombosit (p=0,028), dan Leukosit (p=0,011), sehingga dapat disimpulkan bahwa terdapat penurunan fungsi darah yang signifikan ditandai dengan adanya penurunan signifikan pada parameter hemoglobin, trombosit dan leukosit sebelum kemoterapi I dan sesudah kemoterapi III BOM-Karboplatin, sehingga diperlukan monitoring ketat terhadap fungsi darah pasien yang menerima kemoterapi BOM-Karboplatin di RSUP Sanglah Denpasar.Kata kunci: BOM-Karboplatin, fungsi darah, kanker serviks, kemoterapi, RSUP Sanglah, toksisitasThe Difference of Kidney, Heart and Blood Function on Cervical Cancer Patients with Chemotherapy, Bleomycin, Oncovin®, Mitomycin and Carboplatin (Case Study in Sanglah General Hospital, Denpasar in 2015) Oncovin® bleomycin mitomycin-carboplatin (BOM-carboplatin) regimen as chemotherapy is inseparable from the side effects it can caused which is toxicity to organs including the kidneys, liver, and blood where the toxicity in the kidneys can be indicated by the parameter of Serum Creatinine and Blood Urea Nitrogen (BUN), the occurrence of toxicity in the liver can be measured by the parameters of SGOT and SGPT, and toxicity to blood function can be indicated by the value of hemoglobin, platelets, leukocytes. The absence of data on the toxic effects of chemotherapy BOM-carboplatin in patients with squamous cell cervical cancer stage IIB–IIIB in Sanglah General Hospital in Denpasar, had made this research conducted through monitoring of kidney, liver and blood function. This study is an observational case study of nine patients who were followed for three rounds of chemotherapy from February to August 2015. Data of creatinine serum, BUN, SGOT, SGPT, hemoglobin, platelets, and leukocytes were analyzed using paired t-test for the data that were normally distributed and Wilcoxon test for the data that were not normally distributed with a confidence level of 95% and was said to be significantly different when p<0.05. The results of this case study demonstrated the value of serum creatinine (p=0.530), BUN (p=0.553), SGOT (p=0.162), SGPT (p=0.054), hemoglobin (p=0.034), platelets (p=0.028), and leukocytes (p=0.011) so it could be concluded that there was a significant decrease of blood function which could be characterized by a significant decrease in the parameters of hemoglobin, platelets and leucocytes before chemotherapy I and after chemotherapy III BOM-carboplatin, so it required strict monitoring of the blood function of the patients who received chemotherapy BOM-carboplatin in Sanglah General Hospital in Denpasar.Keywords: BOM-carboplatin, blood function, cervical cancer, chemotherapy, Sanglah General Hospital, toxicity
Studi Epidemiologis dan Laboratoris: Peran Metformin pada Kanker Kolorektal Yudhani, Ratih D.
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (528.395 KB) | DOI: 10.15416/ijcp.2016.5.4.258

Abstract

  Data GLOBOCAN tahun 2012 menunjukkan kanker kolorektal merupakan keganasan urutan ketiga terbanyak di dunia. Di Indonesia, berdasarkan data WHO tahun 2014, kanker ini menempati urutan kedua terbanyak pada laki-laki dan ketiga pada perempuan. Studi epidemiologis menunjukkan diabetes melitus terkait erat dengan insidensi kanker secara umum dan meningkatkan risiko kanker kolorektal sebesar 30%. Beberapa studi epidemiologis melaporkan terapi metformin pada penderita diabetes menurunkan risiko insidensi kanker dan didukung studi laboratorik yang menunjukkan metformin mampu menghambat pertumbuhan dan proliferasi sel kanker melalui mekanisme utama mempengaruhi jalur AMPK/mTOR. Metode dalam review ini adalah penelusuran data berbasis Pubmed, Scopus dan Google Scholar dan tanpa pembatasan Index Factor dengan kata kunci metformin, colorectal cancer dan colon cancer, pada jurnal gratis maupun jurnal berbayar. Review ilmiah ini bertujuan memberikan pemahaman baru terkait aktivitas antikanker metformin dan potensinya untuk digunakan sebagai terapi preventif maupun adjuvan terapi pada kanker, khususnya kanker kolorektal.Kata kunci: Diabetes, kanker, kolorektal, metforminEpidemiological and Experimental Studies:  The Role of Metformin on Colorectal CancerGLOBOCAN data in 2012 showed colorectal cancer was the third leading cancer worldwide. In Indonesia, based on WHO data in 2014, colorectal cancer was the second common cancer ini men and third cancer in women. Epidemiological studies showed that diabetes mellitus have a correlation with the incidence of cancer and increase colorectal cancer risk by 30%. Some of epidemiological study showed that metformin therapy in diabetes patient reduce the risk of cancer incidence. It supported by experimental study which showed that metformin inhibit the growth and proliferation of cancer cells by influence the AMPK/mTOR pathway as a main role. The method was literature review based on publication at Pubmed, Scopus, and Google Scholar with keywords “metformin, colorectal cancer”, “metformin, colon cancer”, without index factor limitation in free journal and paid journal. The aim of this review is to give a new insight of metformin activity as anti-cancer and its potential for both preventif and adjuvant cancer therapy, especially for colorectal cancer.Keywords: Cancer, colorectal, diabetes, metformin
Pengaruh Penilaian Prestasi Kerja dan Kompensasi terhadap Kinerja Tenaga Teknis Kefarmasian Non-PNS Instalasi Farmasi RSUP Dr. Hasan Sadikin Winarni, Rina; Muhtadi, Ahmad; Surahman, Emma
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (630.742 KB) | DOI: 10.15416/ijcp.2016.5.4.278

Abstract

Kinerja adalah hasil kerja secara kualitas dan kuantitas yang dicapai oleh seorang pegawai. Penelitian ini bertujuan untuk mengetahui pengaruh penilaian prestasi kerja dan kompensasi terhadap kinerja pegawai Tenaga Teknis Kefarmasian Non-PNS Instalasi Farmasi. Metode yang digunakan adalah metode survei analitik dengan rancangan potong lintang. Sampel yang digunakan 102 karyawan instalasi farmasi kompetensi Tenaga Teknis Kefarmasian dengan status kepegawaian Non-PNS. Pengumpulan data menggunakan kuesioner dan dianalisis menggunakan analisis jalur. Hipotesis pertama penilaian prestasi kerja memengaruhi kinerja (t hitung 4,038 > t tabel 1,984). Hipotesis kedua adalah kompensasi memengaruhi kinerja (t hitung 3,739 > t tabel 1,984). Hipotesis ketiga adalah penilaian prestasi kerja memengaruhi kompensasi (t-hitung 10,208 > t tabel 1,984). Penilaian prestasi kerja dan kompensasi berpengaruh sebesar 51,68% terhadap kinerja pegawai. Penilaian prestasi kerja dan kompensasi masing‑masing berpengaruh sebesar 27% dan 24,68% sedangkan 48,32% merupakan variabel lain yang tidak diteliti. Kinerja Tenaga Teknis Kefarmasian Non-PNS Instalasi Farmasi RSUP Dr. Hasan Sadikin dipengaruhi oleh penilaian prestasi kerja dan kompensasi dengan total pengaruh sebesar 51,68%.Kata kunci: Kinerja, kompensasi, penilaian prestasi kerja, tenaga teknis kefarmasianThe Impact of Performance Appraisal and Compensation to Performance of Pharmacy Technical Personnel Non-Civil Servants at Hasan Sadikin Hospital Abstract Performance is the result of the quality and quantity of work achieved by an employee. This study aimed to determine the effect of performance appraisal and compensation to performance of Pharmacy Technical Personnel Non Civil Servants. This study used analytic survey with cross-sectional study design. The sample are 102 pharmacy employees. Data was collected by using questionnaires and analyzed using path analysis. The first hypothesis is the performance appraisal affect the performance (t value 4,038 > t table 1.984). The second hypothesis is the compensation affects the performance (t value 3.739 > t table 1.984). The third hypothesis is the performance appraisal affects the compensation (t value 10.208 > t table 1.984). Performance appraisal and compensation affected employee performance by51.68%. Performance appraisal and compensation affected employee performance by 27% and 24.68% respectively, while 48.32% is other variable that is not investigated. Performance of Pharmacy Technical Personnel Non Civil Servants in RSUP DR. Hasan Sadikin is influenced among others by the performance appraisal and compensation with a total effect of 51.68%.Keywords: Compensation, performance, performance appraisal, pharmacy technical personnel
Gambaran Kepatuhan Pengobatan Pasien Diabetes Melitus Tipe 2 di Puskesmas Daerah Istimewa Yogyakarta Rasdianah, Nur; Martodiharjo, Suwaldi; Andayani, Tri M.; Hakim, Lukman
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (521.668 KB) | DOI: 10.15416/ijcp.2016.5.4.249

Abstract

Prevalensi diabetes melitus berdasarkan hasil riset kesehatan dasar (Riskesdas, 2013) tertinggi di Indonesia terdapat di provinsi DI Yogyakarta.terdapat di provinsi DI Yogyakarta. Diabetes melitus merupakan penyakit kronis yang membutuhkan pengobatan jangka panjang dan kompleks dimana salah satu penentu keberhasilan terapi bergantung pada kepatuhan penggunaan obat. Tujuan penelitian ini untuk mengetahui gambaran karakteristik pasien meliputi jenis kelamin, usia, tingkat pendidikan, durasi penyakit, komorbid, dan penggunaan ADO terhadap kepatuhan pasien diabetes melitus tipe 2. Penelitian ini menggunakan metode observasional dengan rancangan analisis potong lintang yang dilakukan secara retrospektif terhadap 123 pasien diabetes melitus tipe 2 rawat jalan di puskesmas daerah Yogyakarta pada bulan Agustus–September tahun 2015. Metode pengambilan sampel menggunakan teknik accidental sampling. Instrumen penelitian berupa lembar pengambilan data dan kuesioner Morisky Medication Adherence MMAS-8. Data dianalisis menggunakan Chi-Square. Hasil penelitian menunjukkan bahwa secara keseluruhan tingkat kepatuhan pasien diabetes melitus tipe 2 berada pada tingkat kepatuhan rendah. Hubungan antara pengaruh karakteristik pasien: jenis kelamin (p=0,275), usia (p=0,473), tingkat pendidikan (p=0,157), durasi penyakit (p=0,097), jumlah komorbid (p=0,79), dan ADO (p=0,401) terhadap tingkat kepatuhan tidak signifikan (p>0,05).Kata kunci: Diabetes melitus tipe 2, karakteristik pasien, kepatuhan The Description of Medication Adherence for Patients of Diabetes Mellitus Type 2 in Public Health Center Yogyakarta According to the Basic Health Research (Riskesdas 2013), the highest prevalence of diabetes mellitus in Indonesia is in Yogyakarta. Diabetes mellitus is chronic disease that needs the complex and a long term medical treatment, one of the success factor in the therapy depends on the patient adherence. The purpose of this research was to know and describe patient’s characteristics including gender, age, education, duration of the disease, comorbid, AOD usage through the adherence of type 2 diabetes mellitus. This research used an observational method with cross-sectional analysis that conducted retrospectively to 123 outpatients with diabetes mellitus type 2 in Yogyakarta Primary Health Care during August–September 2015. The sampling method the accidental sampling technique. Morisky Medication Adherence (MMAS) questionnaire was used and analyzed with Chi Square. The result of this research showed that the entirety of medication’s adherence level is low. The correlation between patients characteristic, gender (p=0.275), ages (p=0.473), educational level (p=0.157), disease’s duration (p=0.097), number of cormobid (p=0.79), and ADO (p=0.401) against the medication’s adherence level were not significant (p>0.05).Keywords: Adherence, diabetes mellitus type 2, patient characteristics
Potensi Interaksi Obat-Obat pada Resep Polifarmasi: Studi Retrospektif pada Salah Satu Apotek di Kota Bandung Herdaningsih, Sulastri; Muhtadi, Ahmad; Annisa, Nurul
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.424 KB) | DOI: 10.15416/ijcp.2016.5.4.288

Abstract

  Resep polifarmasi sangat umum terjadi dalam peresepan pasien rawat jalan maupun rawat inap di setiap fasilitas kesehatan. Polifarmasi dapat meningkatkan risiko terjadinya interaksi obat-obat atau Drug-drug Interactions (DDI’s) yang sebagian besar akan menimbulkan dampak merugikan dalam terapi pasien. Tujuan dari studi ini yaitu untuk menilai potensi DDI’s pada resep rawat jalan di salah satu apotek di kota Bandung. Data diproses melalui www.drugs.com database atau Drug Interactions Checker. Studi ini memaparkan prevalensi dan mengklasifikasikan jenis interaksi potensial berdasarkan level interaksi yaitu mayor, moderat dan minor. Total resep rawat jalan periode Januari–Maret 2014 adalah sebanyak 352 lembar resep yang didalamnya terdapat sebanyak 1.111 R/. Dari total keseluruhan jumlah lembar resep, terdapat 197 (55,97%) lembar resep yang masuk dalam kriteria inklusi. Sebanyak 121 lembar resep terdapat DDI’s potensial sebesar 34,38%. Keseluruhan DDI’s potensial yang terjadi adalah sebanyak 194 interaksi. DDI’s potensial mayor sebanyak 25 (12,89%), moderat sebanyak 134 (69,07%) dan minor 35 (8,04%). DDI’s terbanyak terdapat dalam kategori mayor dan moderat yang membutuhkan perhatian lebih dan tindakan pencegahan terhadap DDI’s potensial yang mungkin terjadi oleh dokter dan apoteker untuk memaksimalkan efektivitas terapi pasien.Kata kunci: Interaksi obat-obat, pasien rawat jalan, resep polifarmasiPotential of Drug-Drug Interaction in Polypharmacy Prescription: Retrospective Study on a Drugstore in Bandung Abstract Polypharmacy prescription very commonly occurs on prescribing the outpatient and inpatient in every health facility. Polypharmacy may increase the risk of Drug-drug Interactions (DDI’s) which mostly causes harm impact in the patient’s therapy. The aim of this study was to measure the potential of DDI’s on the outpatient prescription in one of the drugstore in Bandung. The data was processed through www. drugs.com database or Drug Interactions Checker. This study described the prevalence and classification of potential interactions based on interaction level of major, moderate, and minor. The number of outpatient prescription on January–March 2014 was 352 sheets of prescriptions with 1.111 R/. From overall numbers of prescriptions, there were 197 (55.97%) sheets of prescriptions on inclusion criteria. In 121 prescriptions, there were 34.38% of DDI’s potential. All of DDI’s potential occurs was 194 interactions. The major DDI’s potential of 25 (12.89%), moderate of 134 (69.07%) and minor of 35 (8.04%). The most of DDI’s found in major and moderate level need more attention and prevention aid against DDI’s potential that may occur by doctors and pharmacists to maximize the effectiveness of patient’s therapy.Keywords: Drug-drug Interactions (DDI’s), outpatient, polypharmacy prescription
Studi Penggunaan Antibiotik Berdasarkan ATC/DDD dan DU 90% di Bagian Bedah Digestif di Salah Satu Rumah Sakit di Bandung Febrina Mahmudah; Sri A. Sumiwi; Sri Hartini
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2956.36 KB) | DOI: 10.15416/ijcp.2016.5.4.293

Abstract

  tidak tepat dapat menimbulkan berbagai masalah, di antaranya pengobatan akan lebih mahal, efek samping lebih toksik, meluasnya resistensi dan timbulnya kejadian superinfeksi yang sulit diobati. Tujuan penelitian ini adalah untuk mengetahui pola penggunaan antibiotik pada pasien bedah digestif di salah satu rumah sakit di Bandung. Data penggunaan antibiotik diperoleh dari Instalasi Rekam Medis pada Juli–Desember 2013. Data diperoleh dengan metode ATC/DDD dan DU 90%. Penelitian ini merupakan penelitian deskriptif dengan studi retrospektif yang diambil dari catatan medik untuk menilai kuantitas dan kualitas penggunaan antibiotik. Sampel diambil dengan cara simple random sampling. Hasil penelitian menunjukkan bahwa dari 208 catatan medik didapatkan total penggunaan antibiotik 17,9 DDD/100 hari rawat dan antibiotik yang masuk dalam DU 90% yaitu seftriakson (8,77 DDD/100 hari rawat), metronidazol (4,61 DDD/100 hari rawat), sefiksim (1,09 DDD/100 hari rawat), sefepim (0,85 DDD/100 hari rawat), siprofloksasin (0,73 DDD/100 hari rawat), dan meropenem (0,42 DDD/100 hari rawat). Hasil penelitian menunjukkan bahwa secara kuantitas penggunaan antibiotik yang paling banyak adalah seftriakson sebesar 8,77 DDD/100 hari rawat dan antibiotik yang masuk dalam segmen 90% yaitu seftriakson, metronidazol, sefiksim, sefepim, siprofloksasin, dan meropenem.Kata kunci: ATC, DDD, kuantitas, studi penggunaan antibiotikStudy of the Use of Antibiotics with ATC/DDD System and DU 90% in Digestive Surgery in Hospital in Bandung Abstract Antibiotics are the most widely prescribed medicines in the hospital. Improper use of antibiotics can cause various problems, such as treatment will be more expensive, more toxic side effects, and the emergence of widespread resistance superinfection events that are difficult to treat. The objective of this study was to determine quantity and pattern of antibiotic usage in hospitalized patients at one hospital in Bandung. Sample were taken by simple random sampling method. The quantity of antibiotics usage was assessed by counting the Defined Daily Dose (DDD)/100 patient days and DU 90%. Based on 208 patient medical records, it was found that total antibiotic usage was 17.9 DDD/100 patient days and antibiotics were included in the DU 90% is ceftriaxone (8.77 DDD/100 patient days), metronidazole (4.61 DDD/100 patient days), cefixime (1.09 DDD/100 patient days), cefepime (0.85 DDD/100 patient days), ciprofloxacin (0.73 DDD/100 patient days) and meropenem (0.42 DDD/100 patient days. The results showed that the use of antibiotics in quantity at most is ceftriaxone for 8.77 DDD / 100 days of hospitalization and antibiotics included in segment 90% were ceftriaxone, metronidazole, cefixime, cefepime, ciprofloxacin, and meropenem.Keywords: ATC, DDD, quantity, study of the use of antibiotics
Validasi Kuesioner Skala Kelelahan FACIT pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Rutin Jhonson P. Sihombing; Lukman Hakim; Tri M. Andayani; Fredie Irijanto
Indonesian Journal of Clinical Pharmacy Vol 5, No 4 (2016)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (771.479 KB) | DOI: 10.15416/ijcp.2016.5.4.231

Abstract

Anemia sangat umum terjadi pada pasien penyakit ginjal kronis (PGK). Salah satu akibat dari anemia adalah terjadinya kelelahan sehingga pasien mengalami penurunan kualitas hidup. Kuesioner Skala Kelelahan Functional Assessment Chronic Illness Therapy (FACIT) adalah suatu instrumen untuk mengetahui tingkat kelelahan pasien. Di Indonesia, kuesioner Skala Kelelahan FACIT belum pernah divalidasi. Tujuan penelitian ini adalah untuk memvalidasi kuesioner Skala Kelelahan FACIT versi Indonesia sebagai salah satu instrumen pengukuran kualitas hidup pasien. Skala Kelelahan FACIT diterjemahkan kedalam bahasa Indonesia dan dibagikan kepada pasien PGK yang menjalani hemodialisis rutin di rumah sakit akademik di Yogyakarta pada periode Mei–Oktober 2015. Validitas dievaluasi dengan uji Pearson correlation dan reliabilitas dievaluasi dengan uji Cronbach alpha. Hasil uji validitas menunjukkan semua butir pertanyaan valid karena nilai r hitung lebih besar dari nilai r tabel=0,279 dan reliabel karena r11=0,646>0,6 yang menunjukkan bahwa instrumen kuesioner reliabel. Kesimpulannya adalah kuesioner Skala Kelelahan FACIT versi Indonesia merupakan suatu pengukuran yang ringkas dan valid untuk memonitor gejala anemia dan efeknya pada pasien penyakit ginjal kronis.Kata kunci: FACIT, hemodialisis, penyakit ginjal kronis, validasi Validation of Indonesian Version of FACIT Fatigue Scale Questionnaire in Chronic Kidney Disease (CKD) Patients with Routine Hemodialysis Anemia is common in Chronic Kidney Disease (CKD). One of anemia consequences is fatigue which can lead to decrease in quality of life. Functional Assessment Chronic Illness Therapy (FACIT) Fatigue Scale is an instrument to measure patient’s score of fatigue. This questionnaire is not validated yet in Indonesia. The aim of this study is to validate Indonesian version of Functional Assessment Chronic Illness Therapy (FACIT) Fatigue Scale as an instrument for patient’s quality of life. FACIT Fatigue Scale was translated into Indonesian and administrated to CKD patients with routine homodialysis in an academic hospital in Yogyakarta on May until October 2015. The validity was evaluated by Pearson correlation test and the reliability was evaluated by Cronbach’s alpha test. Validity test showed that all of the questions were valid because r count was bigger than r table=0,279 and reliable because r11=0,646>0,6. In conclusion, Indonesian version of FACIT Fatigue Scale was a brief and valid to monitor important symptom and its effect on CKD patients with routine hemodialysis.Keywords: Chronic kidney disease, FACIT, hemodialysis, validity

Page 1 of 2 | Total Record : 16

 1   2 

Filter by Year

2016 2016


Reset
Filter By Issues
All Issue Vol 14, No 3 (2025) Vol 14, No 2 (2025) Vol 14, No 1 (2025) Vol 13, No 3 (2024) Vol 13, No 2 (2024) Vol 13, No 1 (2024) Vol 12, No 3 (2023) Vol 12, No 2 (2023) Vol 12, No 1 (2023) Vol 11, No 4 (2022) Vol 11, No 3 (2022) Vol 11, No 2 (2022) Vol 11, No 1 (2022) Vol 10, No 4 (2021) Vol 10, No 3 (2021) Vol 10, No 2 (2021) Vol 10, No 1 (2021) Vol 9, No 4 (2020) Vol 9, No 3 (2020) Vol 9, No 2 (2020) Vol 9, No 1 (2020) Vol 8, No 4 (2019) Vol 8, No 3 (2019) Vol 8, No 2 (2019) Vol 8, No 1 (2019) Vol 7, No 4 (2018) Vol 7, No 3 (2018) Vol 7, No 3 (2018) Vol 7, No 2 (2018) Vol 7, No 2 (2018) Vol 7, No 1 (2018) Vol 7, No 1 (2018) Vol 6, No 4 (2017) Vol 6, No 4 (2017) Vol 6, No 3 (2017) Vol 6, No 3 (2017) Vol 6, No 2 (2017) Vol 6, No 2 (2017) Vol 6, No 1 (2017) Vol 6, No 1 (2017) Vol 5, No 4 (2016) Vol 5, No 4 (2016) Vol 5, No 3 (2016) Vol 5, No 3 (2016) Vol 5, No 2 (2016) Vol 5, No 2 (2016) Vol 5, No 1 (2016) Vol 5, No 1 (2016) Vol 4, No 4 (2015) Vol 4, No 4 (2015) Vol 4, No 3 (2015) Vol 4, No 3 (2015) Vol 4, No 2 (2015) Vol 4, No 2 (2015) Vol 4, No 1 (2015) Vol 4, No 1 (2015) Vol 3, No 4 (2014) Vol 3, No 4 (2014) Vol 3, No 3 (2014) Vol 3, No 3 (2014) Vol 3, No 2 (2014) Vol 3, No 2 (2014) Vol 3, No 1 (2014) Vol 3, No 1 (2014) Vol 2, No 4 (2013) Vol 2, No 4 (2013) Vol 2, No 3 (2013) Vol 2, No 3 (2013) Vol 2, No 2 (2013) Vol 2, No 2 (2013) Vol 2, No 1 (2013) Vol 2, No 1 (2013) Vol 1, No 4 (2012) Vol 1, No 4 (2012) Vol 1, No 3 (2012) Vol 1, No 3 (2012) Vol 1, No 2 (2012) Vol 1, No 2 (2012) Vol 1, No 1 (2012) Vol 1, No 1 (2012) More Issue