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INDONESIA
Majalah Kedokteran Gigi Indonesia
Published by Universitas Gadjah Mada
ISSN : 24600164     EISSN : 24422576     DOI : https://doi.org/10.22146/majkedgiind.36959
Core Subject : Health,
Dentistry
Arjuna Subject : -
Articles 12 Documents
 1   2 
Search results for , issue "Vol 10, No 2 (2024): August" : 12 Documents clear
Unsuspected oral pigmentation in patient with systemic disease histories Sari, Tjut Intan Permata; Agustina, Dewi; Dean, Nathaniel
Majalah Kedokteran Gigi Indonesia Vol 10, No 2 (2024): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.94667

Abstract

Oral pigmentation refers to a pigmented lesion on the oral mucosa, caused by one or more pigments that accumulate, resulting in tissue color change. Pigment lesions can vary in size, color, and location, and may range from benign to malignant. The role of the dentist is crucial in recognizing and classifying these lesions to facilitate proper treatment. This case report describes oral pigmentary abnormalities suspected to be indicative of an undiagnosed systemic disease. A 52-year-old woman presented with complaints of brittle teeth. Upon examination, changes in her oral mucosa were noted, and she was found to have uncontrolled type 2 diabetes mellitus, as well as a history of hysterectomy due to a tumor. Intraoral and extraoral examination revealed macular pigmentation on the mucosa and skin, particularly on the extremities. After further investigation, we concluded that early detection of polyps is important, as these patients may be susceptible to neoplasia development in areas outside the intestines. Dentists should be vigilant in recognizing a wide range of lesions that can assist in diagnosing conditions beyond oral health, to ensure patients receive appropriate treatment.
Combining antimicrobial photodynamic therapy with curcumin and with methylene blue against S. mutans Hariyani, Ninuk; Setyowati, Dini; Armadanty, Talsha Irzaputri; Amiati, Devy Ratriana; Dani, Anugrah Putra; Shoaib, Lily Azura; Shanbhag, Namita
Majalah Kedokteran Gigi Indonesia Vol 10, No 2 (2024): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.94888

Abstract

ntimicrobial photodynamic treatment (aPDT) is a treatment method that links a light source to a photosensitizing carrier. There is no clear standardization regarding the exact therapeutic concentration when it is combined with curcumin or methylene blue, and there is no comparison of their activities toward S. mutans. We aimed to assess the best composition of the combination of aPDT and curcumin and with the combination of aPDT and methylene blue in reducing the number of S. mutans biofilms. The searches were carried out in Pubmed, ScienceDirect, and Proquest from 2015 to April 2023; collecting in-vitro and in-vivo research. Two authors independently reviewed studies, assessed their quality and eligibility, then extracted the data. 14 articles that met the inclusion criteria were retained. The final results were then grouped into 2, showing the effectiveness for a combination of aPDT and methylene blue and of aPDT and cucumin (9 and 5 articles, respectively). Each combination has different aPDT properties. The combination of aPDT and methylene blue is effective in reducing S. mutant biofilm in 660 nm diode laser wavelength and 40 mW output power. Furthermore, aPDT combined with curcumin is effective in reducing S. mutants biofilm in a wavelength of 405 nm and an irradiation time of 50-150 seconds. The addition of EDTA in a combination of aPDT and curcumin could increase its effectivity.

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