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Biology, Medicine, & Natural Product Chemistry

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Published by Universitas Islam Negeri Sunan Kalijaga Yogyakarta

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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for researchers in these fields, and with the aim to set international standards in their methodology.

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Articles 5 Documents

Search results for , issue "Vol 4, No 2 (2015)" : 5 Documents clear

Effect of Lunasia amara Blanco on Sperm Number, Sperm Motility, and Testicular Histology of Male Rats Muhammad Ja’far Luthfi
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Sanrego (Lunasia amara), has been used in the folk medicine to increase and/or to treat male fertility. However there is no scientific evidence to confirm the positive effect of the plant on an improvement of male fertility. The objective of this research was to study the effects of the plant (on adult Sprague-Dawley male rats) at the doses of 30 mg/kg, 60 mg/kg, and 90 mg/kg on the sperm count, motility, and testicular histology. Administration were given by force-feeding between 10.00 am and 12.00 pm daily for a period of 42 days followed by sperm quality analysis and testicular histology evaluation. The sperm analysis showed that the sanrego increased the sperm count and sperm motility. The testicular histology also revealed positive effect of the plant on spermatogenesis. Overall the present study showed the sanrego is potential plant to increase male fertility.

Medicinal Plants: A Prospect in Developing Male Fertility Enhancing Agent Muhammad Ja’far Luthfi; Mahanem Mat Noor; Jalifah Latip
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Medicinal plants have been a revolutionary breakthrough in the treatment of male sexual dysfunction. Traditional medicine based on a holistic philosophy is quite different with the practice of “western” medicine. Phytochemical substances focus their mechanisms of healing to the root of cause, i.e. the inability of controlling the proper function of the whole body system. Hence, medicinal plants manage sexual dysfunction and male fertility in the frame of sexual dysfunction as a whole entity. Some previous researches prove that the use of medicinal plants have a good impact in the treatment of a variety of male sexual problems. This paper will discuss several important aspects of aphrodisiac plants and preliminary study regarding them in Indonesia. Difficulties inherent to activity guided isolation and the specific requirements of bioassays are also discussed.

Krokot (Portulaca oleracea L) As a Natural Sensitizer for TiO2 Dye-sensitized Solar Cells: The Effect of Temperature Extract Reyza Anni Mufidah; Khamidinal Khamidinal; Endaruji Sedyadi; Didik Krisdiyanto
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

The solar cell is formed by a sandwich structure, in which two electrodes flank the primary electrolyte that is containing redox I-/based on PEG (Polyethylene Glycol). The working-electrode which is TiO2 layer on an ITO glass substrate is sensitized with krokot dye as the electron donor. The counter electrode is a layer of carbon. The fabrication cell is immersed with the krokot dye with 40°C, 50°C, 60°C extract temperature. The result of the UV-Vis shows that the absorption of wave-length from dye extract of krokot is located in the visible region with the absorbance peak in 420,5 nm and 665,5 nm which are the peak of chlorophyll. For the UV-Vis solid system, there are the highest band gap in 50°C extract temperature that make the capability of absorption toward UV spectrum is large. Furthermore, in the functional group analysed by FT-IR, there are shiften-carbonil and hydroxyl group after they are sensitized. From the current and voltage test with I-V meter keithley 2400 is resulted that on the 50°C extract temperature produces the highest efficiency of reaches which is 2.63 x 10-3 %.

Tapak Liman (Elephantopus scaber L) As Immunostimulant and Its Effect on Lymphocyte Differentiation in Mice BALB/C Marmi Kelik
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Tapak liman (Elephantopus scaber L) is one of the plants that have medicinal properties and has been used for maintenance and improvement of health and disease treatment. The purpose of this study was to determine the effect of extracts of Tapak Liman (Elephantopus scaber L) as immunostimulant to the development of lymphocytes in mice BALB / C. The procedure of this study was to test aqueous extracts in vivo with various treatments (control, treatment of 0.5 g / kg, 1.0 g/ kg, 2.0 g / kg) in healthy mice BALB / C for 2 weeks. After the treatment carried out analysis of the percentage and number of cells that express CD4+, CD8+ and CD4+ CD8 + in thymus organ, using flowcytometry. Analysis of data using one-way ANOVA followed Tukey's test with SPSS. From the analysis showed that the extract of Tapak liman at various doses showed no significant effect on the percentage expression of CD4 + CD8 + and CD4 + CD8 + in thymus organs. While the analysis of the number of cells, extracts of Tapak liman show its effect on the number of cells that express CD4+, CD8 + and CD4 + CD8 + in thymus organs. Concentration of 1.0g / kg of mice showed a good effect on the increase in T helper cells (CD4 +), cytotoxic T cells (CD8 +) and Prothymosit cells (CD4 + CD8 +).

Antioxidant Potential of Black, Green and Oolong Tea Methanol Extracts Wahyu Widowati; Tati Herlina; Hana Ratnawati; Gabriella Constantia; I Dewa Gde Sathya Deva; Maesaroh Maesaroh
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Degenerative diseasesandchronicdiseasesare oftencausedbyoxidativestress. Oxidative stress caused by free radicals. Antixodant as inhibitor are needed to prevent it which is one of antioxidant sources is tea. Tea processinggenerally produce various kinds of teas such as black, green and oolong tea. Tea processing affect thecontent ofphenolic compounds. The aim of the research is to evaluate phytochemical content, totalphenolic content of blacktea, green tea andoolongtea extracts using catechin, quercetin, kaempferol, myricetin as standard, and to evaluate the antioxidative potency of black tea, green tea and oolong tea extracts compared to catechin, quercetin, kaempferol, myricetin. Phytochemical assay using modified Farnsworth method, the antioxidant activity were measured by by its 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging activity. Green tea extract contained highest phenolic and flavonoid. The highest antioxidant activity was green tea extract with IC50=0,487μg/mL. Green tea extract content phenol and flavonoid are higher compared to the other extracts, green tea extract has the highest antioxidant activity.

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