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INDONESIA
Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
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Articles 2 Documents
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Search results for , issue " Vol 2, No 2 (2002)" : 2 Documents clear
Kajian terhadap Pemeriksaan Haemoglobin (Hb) Indriawati, Ratna
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 2, No 2 (2002)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

The prevalence of anemia among pregnant women and under-five-year- old children in Indonesia is still very high. Hemoglobin (Hb) estimation assists in detecting anemia. There are two methods on measuring Hb by colorimetries i.e. Sahli and Talquist. The objective of this study was to compare the value of Sahli and Talquist methods by using the agreement test. This study was conducted in Physiology Laboratory, Faculty of Medicine, Muhammadiyah University of Yogyakarta. A total number of 39 students who took Physiology were enrolled to this study. The Hb level measurement was conducted by trained students. Two students conducted the Hb level measure-ment using Sahli and Talquist methods randomly. Subjects of the study were 39 students consisted of 18 men and 21 women. The age mean was 20 ± 2,2. Using Talquist method, the Hb levels among men were significantly higher than women (p-0.02). Kappa coeffisient was calcu-lated to know the agreement between Sahli and Talquist methods. The Hb levels were catagorized into two groups using cut-off point 12 mg/dl, 10 mg/dl and 8 mg/dl, respectively. The agreement based on those three cut-off point was low, kappa coefficient were 0.24, 0.20 and 0.22, respectively. There were differences on the Hb level measurement between Sahli and Talquist methods (the agreement test with K=0,24; K=0,22 and K=0,20 were low).Prevalensi anemia pada wanita hamil dan anak-anak di bawah lima tahun di Indonesia masih sangat tinggi. Untuk menentukan adanya anemia perlu pemeriksaan kadar hemoglobin (Hb). Pemeriksaan kadar Hb secara kolorimetris ada 2 cara yaitu, metode Sahli dan Talquist Tujuan dari penelitian ini adalah membandingkan hasil pengukuran kadar Hb menggunakan metode Sahli dan Talquist dengan uji kesepakatan. Penelitian ini dilakukan di Laboratorium Fisiologi, Fakultas Kedokteran Univer-sitas Muhammadiyah Yogyakarta. Jumlah subyek 39 orang mahasiswa yang mengambil matakuliah fisiologi. Mahasiswa sebelumnya dilatih dahulu. Dua orang mahasiswa melakukan pemeriksaan Hb dengan metode Sahli dan Talquist, secara acak. Subyek penelitian ini adalah 39 mahasiswa, terdiri dari 18 laki-laki dan 21 perempuan, yang berusia rata-rata 20 +2,2 tahun. Pemeriksaan kadar Hb metode Talquist didapatkan perbedaan bermakna antara kadar Hb laki-laki dan perempuan (p=0,02). Perhitungan dengan koefisien Kappa untuk mengetahui kesepakatan antara metode Sahli dengan Talquist. Kadar Hb dikategorikan diam 2 kelompok menggunakan cut-off point 12 g/dl, 10 g/dl dan 8 g/dl. Uji kesepakatan pada 3 cut¬off point tersebut rendah, koefisien Kappa 0,24,0,20 dan 0,22. Terdapat perbedaan hasil pemeriksaan kadar Hb metode Sahli dan Talquist (uji kesepakatan dengan K=0,24, K=0,22 dan K=0,20 rendah).
Imunitas Tubuh terhadap Cytomegalovirus (CMV) Rachmawaty, Farida Juliantina; Rosita, Linda
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 2, No 2 (2002)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Cytomegalovirus (CMV) infection has been an important health prob-lem recently. The impact of the infection on the fetus i.e. physical disability and mental retardation will decrease the quality of life. Hence, this will influ¬ence the quality of the next generation, as well as becoming a burden of the family and the community. The expensive cost for its laboratorium examamination and therapy has caused some problems. It is therefore, it is important to understand the body immunity toward this viral infection. Cytomegalovirus (CMV) constitutes Herpesviridae family group. This virus has spread around the world, although its replication develops slowly. Cytomegalovirus (CMV) does not stand high temperature and its reservoar is only human. The transmission of this virus needs frequent contacts and inti¬mate relationship with the infected person. A healthy person with good immu¬nity condition is not easily infected by CMV. However, it needs special atten¬tion on susceptible groups i.e. pregnant women with the fetuses they are carrying; and children, as well as humans with bad immunity or who receive organ tranplantation. This infection rarely becomes mononucleosis syndrom. The diagnostic pro-cedure for adult patients are more frequently based on serologic examinations rather than the clinical conditions. The therapy for the CMV infection patient with intra venous Ganciclovir shows good result. Other recommended thera-pies are intra venous Foscarnet and Cidovir, however, they need caution due to their high side effects.Infeksi Cytomegalovirus (CMV) merupakan masalah penting akhir-akhir ini. Dampak yang ditimbulkan pada janin yang terinfeksi berupa kecacatan fisik dan retardasi mental akan menurunkan kualitas hidupnya. Hal ini akan berpengaruh pula terhadap generasi penerus, serta menjadi beban keluarga dan masyarakat. Mahalnya pemeriksaan laboratorium dan pengobatan menimbulkan masalah tersendiri. Dengan demikian perlu diketahui imunitas tubuh terhadap virus ini. Cytomegalovirus (CMV) merupakan kelompok virus dari famili Herpesviridae. Virus ini tersebar di seluruh dunia, namun replikasinya berkembang dengan lambat. CMV tidak tahan terhadap pemanasan dan satu-satunya reservoar adalah manusia. Perlu kontak yang berulang-ulang dan hubungan yang erat dengan penderita untuk dapat tertular virus ini. Pada orang sehat dengan kondisi imunitas yang bagus tidak mudah terinfeksi CMV. Diperlukan perhatian khusus pada kelompok-kelompok yang rentan, yaitu ibu hamil dengan janin yang dikandungnya dan anak-anak, demikian pula pada individu yang jelas-jelas diketahui terjadi penurunan imunitas atau mendapat tranplantasi organ. Infeksi CMV jarang menjadi sindrom mononukleosis. Diagnosis pada orang dewasa lebih banyak ditegakkan berdasar pemeriksaan serologis daripada gejala klinik. Terapi pada penderita dengan Ganciclovir intra vena menunjukkan hasil yang baik. Terapi lain yang dapat direkomendasi adalah Foscamet dan Cidovir intra vena, namun perlu hati-hati karena efek samping yang tinggi.

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