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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 3 Documents
 1 
Search results for , issue " Vol 3, No 2 (2003)" : 3 Documents clear
Tinjauan Keluarga tentang Tempat Terakhir Perawatan pada Pasien di Saat Terakhir Kehidupan Puspitosari, Warih Andan
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 3, No 2 (2003)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Lebih dari seabad yang lalu, perawatan di rumah dan rumah sakit meningkat menjadi tempat kematian, walaupun demikian belum ada penelitian secara nasional yang mengamati kecukupan atau kualitas perawatan pasien stadium terminal di institusi kesehatan dibandingkan dengan perawatan di rumah.
Karsinoma Sel Squamosa Sagiran, -
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 3, No 2 (2003)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Squamous cell carcinoma is a non-melanotic skin cancer that commonly found beside basal cell carcinoma. The lesion is specific with the thickening of stratum corneum of the skin. The common predilection is in the face, it can follow the subsequent process of skin trauma. We reported the case of a 60- year old female with a squamous cell carcinoma in her lower lip. She has been suffering from this disease for 5 years, but there is no metastasis. It has been wide-excised, histo-pathologically showed that the margin of excision is tu¬mor-free.Karsinoma sel squamosa adalah salah satu bentuk keganasan kulit non-melanotik yang sering dijumpai, di samping karsinoma sel basal. Lesinya sangat khas dengan adanya penebalan lapisan tanduk. Predileksi yang sering adalah wajah, dapat mengikuti proses penyembuhan pasca trauma. Tulisan ini melaporkan sebuah kasus seorang perempuan 60 tahun dengan karsinoma sel squamosa pada bibir bawah. Penyakitnya sudah diderita 5 tahun, namun tidak didapatkan metastasis. Telah dilakukan eksisi luas, histopatologis menunjukkan tepi irisan bebas dari tumor.
Tinjauan Risiko dan Manfaat Hormone Replacement Therapy Miladiyah, Isnatin
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 3, No 2 (2003)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Until now, pharmacological options for the management of perimenopausal and postmenopausal syndromes have been dominated by HRT (hormone re¬placement therapy), with either estrogen alone or estrogen plus progestine. In the recent year, several prospective trials of HRT in postmenopausal women had been carried out. The first two studies about the risks and benefits of HRT were carried out by the Women ’s Health Initiative (WHI) and the Heart and Estrogen/progestin Replacement Therapy (HERS). The main focus of these studies were how menopausal woman can best achieves good quality of life. Those studies find that combination therapy with estrogen and progestine is associated with higher risk of stroke, venous thromboembolism, and a slightly risk of myocardial infarction, and breast cancer in women using HRT long term. This review discuss more detail about the risks and benefits of HRT sup¬ported by evidences. In addition, this review propose several recommenda¬tions about the use of HRT regarding those risks and benefits, though pre¬scribing of any HRT can really achieve qood quality of life of menopausal woman.Sampai saat ini pilihan terapi farmakologik untuk mengatasi sindroma perimenopause dan pasca menopause masih didominasi oleh penggunaan HRT {hormone replacement therapy atau terapi sulih hormon), baik dengan estrogen saja atau kombinasi estrogen dengan progestin. Dalam beberapa tahun terakhir, telah banyak penelitian prospektif tentang penggunaan HRT pada wanita pasca menopause. Dua penelitian pertama yang membahas tentang risiko dan manfaat HRT ini adalah dari the Women ’s Health Initiative (WHI) dan the Heart and Estrogen/progestin Replacement Therapy (HERS). Fokus utama penelitian- penelitian ini terutama adalah agar wanita menopause dapat mencapai kualitas hidup yang baik. Hasil dari kedua penelitian tersebut adalah bahwa HRT dikaitkan dengan tingginya risiko mengalami stroke, tromboemboli vena, infark miokard, dan kanker payudara pada penggunaan HRT jangka panjang. Tulisan ini membahas tentang risiko dan manfaat HRT disertai dengan bukti-bukti penelitian yang mendukungnya. Selain itu, tulisan ini juga mengungkap beberapa rekomendasi penggunaan HRT berdasarkan pertimbangan risiko dan manfaat tersebut, sehingga keputusan pemberian HRT benar-benar akan memberikan peningkatan kualitas hidup wanita menopause.

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