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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 5 Documents
 1 
Search results for , issue "Vol 20, No 2: July 2020" : 5 Documents clear
Determination of Stunting Risk Factors Using Spatial Interpolation Geographically Weighted Regression Kriging in Malang Pramoedyo, Henny; Mudjiono, Mudjiono; Fernandes, Adji Achmad; Ardianti, Deby; Septiani, Kurniawati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200250

Abstract

Stunting is the condition toddlers have Stunting is the condition toddlers have less length or height if compared to age. The high percentage of stunting is influenced by several factors, namely access to healthy latrines, quality drinking water, hand washing behavior with soap, coverage of posyandu access and coverage of breast milk 1-6 months, and there are indications that if an area has a high stunting percentage, then there is a possibility that the nearest area has the same condition. So, the statistic method for this research use the spatial interpolation Geographically Weighted Regression Kriging. Geographically Weighted Regression (GWR) is a weighted regression in which the weighting function is used to describe the closeness of relations between regions. The weight used is distance based weight dan weighting by area (contiguity). Ordinary kriging method calculated with semivariogram which is one function to describe and model the spatial autocorrelation between data of a variable and function as a measure of variance. The results showed that based on value GWR model with weight Fixed Gaussian Kernel better to use then the weighted GWR model Rook Contiguity. The Predicted of prevelensi stunting in the form of map based on interpolation GWR Kriging. Keywords: Stunting, GWR, and Kriging.
Suweg Flour (Amorphophallus Campanulatus) Potential Reducing TNF-α Levels in Model Diabetic Rats Setyawati, Ika
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200246

Abstract

Diabetes mellitus (DM) is a chronic disease and it is called as a silent killer because this disease is unrecognized by the diabetics. However, when it is already known the complication is occurred. It is recognized by the increase of blood glucose level (hyperglycemia) as the main character of Diabetes Mellitus (DM). This condition causes the increase of the Reactive Oxygen Species (ROS) in a chronic condition.  Then, insulin resistance is caused by the oxidative stress in fat, muscle and liver tissue. Moreover, insulin resistance produces several oxidative stress mediators including  (TNF- α). This research aims to determine the effect of suweg flour (Amorphophallus campanulatus) on TNF-α level in rats diabetic model. The method used in the research was an experimental laboratory of pre-post control group test conducted in 28 days. The subjects of this research were 25 Rattus Novergicus wistar strains, (P1) positif control (P2), standart (P3) and two treatment groups (P4 and P5). The data were gained by measuring the level of TNF-α before and after receiving the suweg flour enzyme-linked immunosorbent assay (ELISA). The data were analyzed by paired sample t-test. This research showed a significant correlation between suweg flour and TNF-α levels (p = 0.000). A significant correlation was discovered in all treatment groups (P4 and P5). The results of this research can be concluded that the administration of suweg flour (Amorphophallus campanulatus) can decrease of TNF-α levels in rats diabetic model.
Sensitivity of Staphylococcus aureus Isolated from Nasal and Throat of Pre-Clerkship Students to Antibiotics Rahayu, Suci; Widiyanti, Dian; Arsyad, Muhammad
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200251

Abstract

Background: Cases of nosocomial infection are many caused by the bacteria of  S.aureus. Bacteria infection caused by S.aureus may result in various skin and soft tissue infections. The infection may become difficult to treat if the strain of  S.aureus responsible is the methicillin resistant strain or methicillin-resistant Staphylococcus aureus (MRSA). Currently there are two known types of MRSA: Hospital Acquired MRSA/HA-MRSA and Community Acquired MRSA/CA-MRSA. Transmission of the bacteria from one patient to another may be caused by unsterile medical equipment or from the hospital staff, especially pre-clinical students who will work in a hospital. The purpose of this study was to obtained the difference of bacteria colonisations S.aureus from nasal and throat swabs, and the sensitivity patterns of S.aureus when exposed to antibiotics (methicillin, vancomycin, imipenem, penicillin, ofloxacin, ciprofloxacin) and the prevalence of MRSA carriers and also to obtain an understanding of the characteristics of medical drug use through Islamic views. Metodes: This study used descriptive analysis method with samples taken from nasal and throat swabs applied to healthy pre-clinic student from Universitas YARSI. Statistical analysis using Mann-Whitney test in the program SPSS for windows. Results: The results bacteria colonisations S.aureus from nasal swabs was positive (23,3%), while from the throat sample was positive (10%). The results of statistical analysis (Sig. = 0.051 0.05) shows that there is no significant difference between the bacterial colonies of S.aureus originating from the nasal swabs and throat swabs of the pre-clinical students. From 60 samples a positive prevalence of (1.7%) was obtained for MRSA carriers. The result of the sensitivity test shows that the isolated sample of the bacteria S.aureus shows the highest sensitivity to the antibiotic imipenem and almost all the isolated samples show resistance to the antibiotic penicillin. Conclusion: There are more S.aureus bacteria colonies on nasal swabs compared to throat swabs. There was no significant difference between S.aureus bacteria colonization of nose and throat swabs in pre-clinical-students. The positive prevalence of MRSA carrier among pre-clinical-students of Yarsi University was (1.7%). In nasal swabs all isolates were still sensitive to the antibiotics methicillin, imipenem, ofloxacin and ciprofloxacin. But on the nasal swab there were three VISA isolates. In the throat swab, there was one MRSA isolate and one isolate that was resistant to ofloxacin. The inhibition zone of the highest sensitivity was obtained for imipenem antibiotics. Almost all isolates showed resistance to penicillin antibiotics. In Islamic medicine, drugs or antibiotics must not contain unclean and haram objects for human consumption.
Risk Factors of Ovarian Cancer in PKU Muhammadiyah Teaching Hospital Yogyakarta Wenang, Supriyatiningsih; AN, Alfun Dhiya; Pratiwi, Witri Andi; Lelle, Ralph J.; Haier, Joerg
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200247

Abstract

Introduction: Ovarian cancer is non-communicable diseases that has a high mortality rate. In PKU Muhammadiyah Teaching Hospital Yogyakarta in 2014-2017, ovarian cancer is 5th out of all types cancers diagnosed. Most of them are asymptomatic in early stage and come to hospital at late stage. Recognize and identify the risk factors of ovarian cancer are very important to prevent the patient from morbidity and mortality. The purpose of this study was to know the relationship between low parity, infertility, age, and family history with ovarian cancer in PKU Muhammadiyah Teaching  Hospital Yogyakarta.Methods: This study was an observational analytical study with cross sectional design. The sample was medical record of women with ovarian cancer and non ovarian cancer in PKU Muhammadiyah Teaching Hospital Yogyakarta period of April 2014-September 2017 with inclusion and exclusion criteria. Data analysis used chi-square test.Result: The bivariat analysis showed that there is no relationship between low parity with ovarian cancer (p=0,790 OR=0,87; 95% CI 0,305-2,466), there is no relation between infertility with ovarian cancer (p=0,104 OR=2,48; 95% CI 0,815-7,545), and there is no relation between family history with ovarian cancer (p=0,304 OR=3,18; 95% CI 0,315-32,039). But there is a relationship between age with ovarian cancer (p=0,01 OR=0,11; 95% CI 0,022-0,510).Conclusion: There are no relations between low parity, infertility, and family history with ovarian cancer. But there is a relationship between age with ovarian cancer.
Knowledge Level about Thalassemia among High School Students in Pontianak City, West Kalimantan, Indonesia Noeriman, Aisya Rezki; Fitrianingrum, Iit; Armyanti, Ita
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200248

Abstract

Introduction: Thalassemia is a genetic disorder that affect the formation of hemoglobin and has high prevalent in Indonesia. Awareness of genetic screening as one of steps to prevent thalassemia require adequate knowledge about thalassemia. There is no data refers to knowledge about thalassemia among high school student in Pontianak City meanwhile that data is important as initial data to planning thalassemia prevention program. Objective: This study assessed knowledge about thalassemia among high school students in Pontianak City. Method: This descriptive study assessed 100 high school students in Pontianak City chosen by propotionated stratified random sampling according to the number of high school students in each district. Result: Most respondents have poor knowledge about thalassemia (49%) with more female students have good knowledge (27,1%) than male students (10%). Sources of information used by respondents are internet (44%), school (17%), health workers (17%), seminars (10%), relatives/friends (6%), and print media (6%). Conclusion: Many high school students in Pontianak City has poor knowledge about thalassemia (49%) therefore spreading information about thalassemia is essential to be done through the most information source that used by students which is internet (44%) or health education program with school and health workers are involved (17%).       

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