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Pharmacon
Published by Universitas Muhammadiyah Surakarta
ISSN : 14114283     EISSN : 26855062     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Pharmacon: Jurnal Farmasi Indonesia is a collection of publication journals, covering all aspects of Pharmaceutical sciences, including Technology of Formulations, Excipients Optimization, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Drug Synthesize and Development, Molecular Biology, Antibiotic Screening, Metabolite Profiling and Quantification, Clinical Pharmacy, Health and Environmental issues, published by Faculty of Pharmacy, Muhammadiyah University of Surakarta. We look forward to working with pharmaceutical community of researchers as we are intended to serve as a major resource for pharmaceutical information.
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Articles 5 Documents
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Search results for , issue " Vol 14, No 2 (2017)" : 5 Documents clear
Optimasi Konsentrasi Amylum Sagu (Metroxylon rumphii) sebagai Co-Processed pada Pembuatan Tablet Teofilin Laili, Nor; Komala, Annisa' Meyndra; Maulida, Hidayaturrizqika; Suprapto, Suprapto
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.6422

Abstract

Tablet preparations are widely used many people for treatment, so the level of production of tablet preparations is quite large and always develops in its formulation. Excipients are generally used in the form of 95% imported materials which are relatively expensive so that production costs will affect the price of tablet preparations which will be more expensive. Based on these considerations, this study uses Indonesian natural excipient with a relatively low cost in the form of sago amylum. This study combines sago amylum and Avicel pH 101 with 5 concentration variations, 90%: 10% (formula 1), 80%: 20% (formula 2), 70%: 30% (formula 3), 60%: 40% (formula 4), and 50%: 50% (formula 5) which produces a co-processed excipient. This co-processed was applied in the manufacture of the Theophylline tablet as a filler, binder and shredder with the direct compression method and tested based on parameters in the Indonesian Pharmacopoeia V. Data analysis using Design Expert® version 11 software to obtain the optimum formula. The co-processed characterization produced has optimum flow properties which are 11.11 g / sec, compressibility = 3.0%, and the stationary angle = 32.0 ° and evaluation of tablet quality uniformity CV = 10.3, hardness x̅ = 6 , 2 kg, fragility = 1.8%, and 46.2 seconds destroyed time. Based on the analysis by Simplex Lattice Design method, it is proved that the more amylum sago concentration increases friability and decreases hardness, while more of Avicel pH 101 decreases friability  and increases hardness. It is concluded with the Design Expert software analysis, the optimum co-processed formula was obtained in the form of a combination of 50% sago amylum; 18,18% pasta amylum sago and 31.82% Avicel pH 101.
Kajian Drug Related Problems (DRPs) Terhadap Pengobatan Pasien Stroke Iskemik di Rumah Sakit Pusat Otak Nasional Jakarta Periode Januari – Desember 2015 S Meila, Okpri; Rochana, Handika Indri
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.5765

Abstract

This study aims to determine the percentage of DRPs of ptients with ischemic stroke at Brain Center National Hospital Jakarta. Based on data from the WHO 2006, each year there are approximately 13 million new stroke patients of which approximatelly 4,4 million of them die within 12 months.When patients undergo a treatment, most patients achieve optimal results that heal diseases suffered by patients but not least the failure in therapy. Therefore, the contribution required to identify, resolve and prevent problems in drug therapy known as Drug Related Problems (DRPs). The method used in this study is cross sectional. Total sample data obtained as many as 360 samples. The results showed indications without drugs of 55.62%, drugs without indication of 15.17%, drug interactions of 10.11%, patients fail to receive the drug of 7.86%, side effects of 6.18% and less drug selection right of 5.06%. Data show that the highest percentage of DRPs are indications without drugs.
Evaluasi Rasionalitas dan Efektifitas Penggunaan Antibiotik pada Pasien Pneumonia Pediatrik di Instalasi Rawat Inap Rumah Sakit Pusat Jawa Tengah Bestari, Mahardika Putri; Karuniawati, Hidayah
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.6524

Abstract

Pneumonia is a respiratory infections disease are caused by bacterial, viral, fungal and parasitic pathogens that cause deaths in children, especially toddlers and increasing number incidents per year. Treatment of pneumonia treated with antibiotics rational and effective because can improve clinical therapeutic effects, minimize drug toxicity, reduce the incidence of resistance that leads to treatment failure, and more economically. The purpose of this study are to determine the rationale and effectiveness of antibiotic therapy. This study was an observational study with retrospective data retrieval using medical record data of pediatric patients diagnosed pneumonia in center hospital, Central Java. The results of 90 cases studied were 60% of patients treated with single antibiotics and 40% of patients treated with combination antibiotics. The most antibiotics given in single therapy were ampicillin (22,2%), amoxicillin (16,7%), and ceftriaxone (15,6%). While antibiotics in combination therapy was ampicillin with gentamicin 31.2%. rationality result analysis was: right indication 100%; proper patients 100%; appropriate medicines 72,2%; appropriate dose 9,23% and rational antibiotics 6,67%. Giving antibiotics ampicillin with gentamycin effective in eradicating bacteria this could be seen with temperature and leukocyte rate down, antibiotics did not improve on symptoms of patients.
Efek Gliserin sebagai Humectan Terhadap Sifat Fisik dan Stabilitas Vitamin C dalam Sabun Padat Sukmawati, Anita; Laeha, Ms. Nur-ainee; Suprapto, Suprapto
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.5937

Abstract

Glycerin is a humectant that is used frequently for cosmetics, especially in soaps. This study was conducted to determine the influence glycerin on the physical properties of glycerin soap including pH, soap hardness, foam stability, and also on the stability of vitamin C in the soap during 8 weeks storage. Vitamin C is formulated in soap with various concentrations of glycerin i.e 5%, 10% and 20%. Evaluation of the soap preparations include a pH test, soap hardness, foam stability test and evaluation on the stability of vitamin C for 8 weeks and the results obtained will be statistically analyzed using SPSS version 16 for windows by the Kruskal-Wallis method on the results test of pH and soap hardness, and using one way ANOVA method for evaluating foam stability. The results showed that glycerol did not significant influence on the pH value of soap with a significance value of P = 0.26> 0.05, while increasing the concentration of glycerin in the soap increased products softness. The foam stability testing showed that the difference in the concentration of glycerin on soap had no significant effect on improving the stability of foam. The best foam stability was found in vitamin C soap containing glycerine 10%. Glycerin also affected the stability of vitamin C in the soap. The stability of vitamin C is increased related to the increasing glycerin concentration in soap as demonstrated in formula III, which contained 20% glycerin and had 49.48% reducing in level of vitamin C, while the soap containing glycerine 5 % and 10%, had decreased 77.98% and 60.67% respectively in level of vitamin C during the storage period of 8 weeks.
Tingkat Kepuasan Pasien Terhadap Pelayanan Kefarmasian di Apotek Kabupaten Rembang Utami, Sally Astya; Cholisoh, Zakky
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.5990

Abstract

Government regulations regulate pharmaceutical care standards at pharmacies to ensure the quality of pharmaceutical care to patient. The impact of not implementing a good pharmaceutical service activity is that medication errors can occur in the pharmaceutical service process. The study aimed to determine if there is any correlation between customer satisfaction and the application of the standards of pharmaceutical care in Rembang. This is a cross sectional survey research with purposive sampling technique. Data was obtained by distributing questionnaires filled by community pharmacists and patients attending community pharmacies. The study was conducted at 4 (four) community pharmacies in Rembang. Data were analyzed using Pearson correlation. Questionnaires were filled by 4 pharmacists’ measuring aspects of facilities, infrastructure and services. The level of satisfaction of 94 community pharmacies’ patients were measured in 5 dimensions i.e. reliability, assurance, tangibles, empathy and responsiveness. The quality of pharmaceutical care scoring and patients’ satisfaction showed no relationship p (95%; 2 tailed) = 0.503.

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