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ANTIHYPERGLYCEMIC TEST OF ETHANOL EXSTRACT OF DURIAN (Durio zibethinus Murr.) PEEL AGAINTS MALE MICE (Mus Musculus)
Hamsiana -;
Rudi Kartika;
Chairul Saleh
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Diabetes mellitus (DM) is a metabolic disorder and characterized by hyperglycemic circumstances. Hyperglycemic is a condition where the glucose levels ini the blood increased dramatically. One of the pharmacological therapy ia to use ofdrugs that can reduse glucose levels in the blood. Phytochemical test and antihyperglicemic activity from durian (Durio zibethunus Murr.) peel have been carried out. Durio zibethinus Murr. peel was macerated with ethanol 96% then concentrated with rotary evaporators. It obtained rendemen 13.33% . Based on the test result of phytochemistry of secondary metabolites compounds from durian peel showed that etahanol extract containing flavonoid, alkaloid, fenolik, triterpenoid and saponin. Antihyperglicemic activity test use animal test male mice that is injected aloksan. Measurement of blood sugar levels using glucometer and glucose test strip. From antihyperglicemic test it showed that the effectiveness of blood sugar level doses of 36 mg/kg BW from the
THE CORRELATION BETWEEN LEARNING INDEPENDENCE AND STUDENTS LEARNING RESULT IN CHEMISTRY THROUGH THE IMPLEMENTATION OF DISCOVERY LEARNING MODEL ON SALT HYDROLYSIS TOPIC IN MAN 2 SAMARINDA ACADEMIC YEAR 2014/2015
Nurlaili -;
Awalus Sarifah
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Learning independence is related to self-management to achieve learning goals, including learning result. One of the learning models which demands students learning independence is the discovery learning. This study aims to: (1) to measure the students level of chemistry learning independence through the implementation of discovery learning model, (2) to determine students learning result through the implementation of discovery learning model on salt hydrolisis topic, (3) to determine positive correlation between learning independence and students learning result in chemistry through the implementation of discovery learning model on salt hydrolisis topic in MAN 2 Samarinda, academic year 2014/2015.This study is classified as associative research. The population of this study is the whole students of MAN 2 Samarinda, while the sample is class XI Science I, whose number is 31 students. The sample is determined by using purposive sampling method. The learning independence data is obtained from learning independence questionnaire, adapted from assessing academic self-regulated learning and students learning result in chemistry is obtained from post-test and regular quiz. The data then analysed by using Pearson’s product moment correlation. The result showed the students learning independence in percentage as follows: highly independent (12.90%), independent (51.61%), fairly independent (35.48%), less independent (0%) and not independent (0%). The learning results percentage are as follow: very high (9.67%), high (19.35%), medium (51.56%), low (19.35%) and very low (0%). There is a positive correlation between learning independence and learning result on medium level (0.433).
A REVIEW ON ANTIPYRETICS AND THE SYNTHESIS ON THE OXEPINE DERIVATIVES
Nurul Kasyfita
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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A review on antipyretics and the synthesis on the oxepine derivatives has been done. This research was aimed as the early review on the antipyretics and to synthesis the oxepine derivatives from salicylic acid and benzylchloride based on the retrosynthesis approach. This research was supervised by Dr. K.M Lokanatha Rai, M.Sc in the University of Mysore.This research was done by two methods, first is the review based on the proposed functional group which will be potential for the antipyretics substance. Second, is based on the retrosynthesis approach in order to obtain the proposed product through the condensation reaction between salycilic acid and the benzylchloride with the THF solvents stirred of 48 hours formed the oxepine which was then transformed to oxime derivatives and confirmed by the IR spectrums. The proposed product was the oxepine derivatives.The review on the antipyretics showing that the potential functional group to be the antipyretics are: the salicyl alchol nitrogen derivatives; some pyrazolone and amino pyrimidine; benzopyranone derivatives; and aspirin eugenol esters. For this review, the investigated functional groups are still further to be discussed.The result of this research on the synthesis of oxepine derivatives shown that the optimum condition of the reaction between salicylic acid and benzyl chloride is at room temperature with the composition of 4 gram of salicylic acid and 4 ml of benzyl chloride was stirred in THF solvent and KOH for 48 hours. The yield of the product is 1.08 g with the confirmed spectrum of IR are: 3369 cm-1 (-OH); 1659.4 cm-1 (C=N); 1554.92 cm-1 (aromatic); 1088.3 cm-1 (N-O); 1019.83 cm-1 (C-O). It is confirmed as an oxime which is the oxepine derivatives.
ANTIOXIDANT ACTIVITY OF ESSENTIAL OIL AND CRUDE EXTRACTS FROM KAFFIR LIME LEAVES (CITRUS HYSTRIX) IN EAST BORNEO
Netty Maria Naibaho;
Khusnul Khotimah
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Kaffir lime levaes is one of citrus cultivars in Indonesia that used as a food ingredient. The antioxidant activity of essential oil and crude extracts of Kaffir lime leaves in East Borneo was determined.The antioxidant potential of the samples was evaluated using two separate methods, inhibition of free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis 3ethylbenzothiazoline-6-sulphonic acid (ABTS).Results showed that the ethanol extracts were able to reduce the stable free radicals (DPPH and ABTS) with 49,5 μmol TE/mg and 42,8 μmol TE/mg, respectively.The total phenolic compounds were 4,06 μg GAE/mg. The essential oils from fresh leaves showed inhibition (DPPH) and (ABTS) at 5,78μmol TE/mg and 5,12μmol TE/mg, respectively. The strong antioxidant activity of the plant extracts may be attributed to the presence of phenolics.
PROSPECTIVE CRITICAL THINKING AND COGNITIVE STUDENTS BASED LEARNING THROUGH INQUIRY
Abdul Hamid
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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The Study on critical thinking and cognitive prospective students through inquiry-based learning had been conducted. The aim of this study is to determine the critical thinking and cognitive prospects of senior high school students through the free and guided inquiry learning. The data had been gathered by using a quasi-experimental. The first step of this study was using non equivalent control group that was designed for SMA Negeri 11 to see the prospect of guided inquiry and also student’s cognitive and critical thinking. Next step, to improve students cognitive and critical thinking datagathered from SMA Negeri 1 Banjarmasin students to see prospective guided inquiry and free inquiry. The comparison between designed pre test-post test of these 2 groups analyzed.The study shows that (1) guided inquiry learning having more prospect compared to expository learning with value of N-gain 0.71 and 0.62 (2) free inquiry has more prospect in improving critical thinking than guided inquiry with a value of N-gain 0, 48 and 0.47. (3) guided inquiry has more prospect in increasing students cognitive value compared to free inquiry to the value of N-gain of 0.82 and 0.62.
ANTIOXIDANT ACTIVITY TEST OF Acacia sp. BARK EXTRACT
Taufiq Rinda Alkas
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Acacia sp. bark was extracted by using Soxhlet Extractor with acetone : water solvents (4 : 6) for 2 hours, extraction with n-hexane, added by NaCl solution, then hydrolized with aqueous hydrochloric acid and finally the precipitate is recrystalized.The antioxidant activity tests were used in this research: Thiocyanate method and Thiobarbituric acid (TBA) method. Thiocyanate method is done for 10 days and the sample absorbance is measured with UV-Vis Spectrophotometre at λ = 500 nm. The TBA method is done with sample absorbance measurement at λ = 532 nm tor 10 days. In this condition, the sample consisted of the mixture of oleic acid 0,05% in absolute ethanol, phosphate buffer in pH=7 with the extract variation (0,05% and 0,09%), BHT and control. The result showed a positive indication that the extract can be used as a natural antioxidant. This research showed higher concentration of the extract also made higher antioxidant activity.
Minerals, Nutrients and Active Compounds of Rambutan Fruits
Sukemi -
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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The main objective of this essay was to describe the minerals, nutrients and active compounds of rambutan (Nepheliumlappaceum L.) fruits. Flesh fruit of rambutanis a sourceof minerals and ascorbic acid that are needed by human. Its seed oil provides mineral and fatty acid. Its peel contains ellagic acid, corilagin and geraniin that have biological activities, such as antioxidant, anticancer, anti-inflammation, anti-hyperalgesic antiviral, anti-semicarbazide-sensitive amine oxidase (SSAO), and anti-hypertensive. Rambutan is not only consumed as fresh fruits, but also it can be used as sources of food and medicine products.
Problem Analysis Of Inquiry Learning Model Devices That What Happens In Chemistry Teacher At SMAN Samarinda
Maradona -;
Makrina Tindangen;
Erwin -
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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This study aims to determine the problem of Inquiry Learning Devices Model Happens in High School Chemistry Teacher in Samarinda. Subjects in this research were 1 teacher and 1 respondents.Methods of analysis was done qualitatively obtained through observation, interviews, documentation and triangulation and data obtained in the research then described.The results showed that the chemistry teacher is having problems in the preparation of RPP learning device.
HIERARCHICALLY STRUCTURED NATURAL FIBRES AS PLATFORM FOR POINT OF CARE ASSAYS
Dedy H.B. Wicaksono
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Cotton fabric is proposed as an alternative material for low cost point of care devices. Cotton fabrics are vastly available, low cost and flexible. Simple wax patterning method was applied to create hydrophilic channels in cotton fabric. Three-dimensional (3-D) colorimetric microfluidic device was made by folding 2-D pattern along certain predefined lines. 3-D devices show better mixing uniformity between reagents and analyte across the detection zones. On-chip colorimetric calibration is also proposed by putting predefined serially dilutedsamples next to the detection zones. Multiple assays can be integrated within a small surface area by stacking layers of individual assay device separated by a wax-impregnated fabric. Cotton fabric was also used as a platform for conducting Enzyme-Linked Immunosorbent Assay (ELISA). The colorimetric performance is similar to the conventional absorbancebased ELISA, yet with lower cost and shorter time to get results. A second type of device using electrochemical detection principle is also implemented in cotton fabric with three electrode configuration (working, counter and reference electrode), using similar simple and low-cost wax-patterning. In both colorimetric and electrochemical device, comparison with te already popular paper-based device will be discussed. Finally, we present latest results in our lab in which cotton fabrics were used as a novel platform for cell-based assay and cellmanipulationdevice.
USING METACOGNITIVE SKILLS IN LEARNING CHEMISTRY THROUGH PROBLEM SOLVING
Syahmani -
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA
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Have been done study about using metacognitive skills in learning chemistry through problem solving. Metacognitionis the awareness of cognitive processes. By using metacognition, someone does all the activities with full awareness. When students learning chemistry by involving their metacognitive skills, students will be able to observe the relationship between data in the problem with the prior knowledge, to re-examine its accuracy, as well as solving acomplex problem with the simple steps, tries to regulate and improve their cognitive processes. This paper aims is prepared in order to build a mindset learning chemistry through problem solving that involve students metacognitive skills. Metacognitive skills to form a competent student resources, who perform all acts by full awareness. Always make good representing problem, planning, monitoring, evaluating, and transfering their action. The i-SMART model helps students to solve problems in a systematical way and supported scaf folding metacognitive questioning. So, metacognitive support during the solution process in problem solving chemistry more effective..