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INDONESIA
Indonesian Journal of Cancer
ISSN : 19783744     EISSN : 23556811     DOI : -
Core Subject : Health,
The Indonesian Journal of Cancer (official journal of the Dharmais Cancer Center Hospital) is a peer-reviewed, quarterly, open access journal. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical cancer research. The journal publishes original research articles, case reports, systematic literature reviews, and letters to the editor under the following categories: Cancer prevention, diagnosis, surgery, systemic therapy, radiotherapy, paliative therapy, and molecular biology.
Arjuna Subject : -
Articles 6 Documents
Search results for , issue " Vol 8, No 2 (2014): April-Juni 2014" : 6 Documents clear
Risiko Kanker Payudara pada Pengguna Obat-obatan Hormonal PURWANTO, DENNI JOKO; REUWPASSA, JAUHARI OKA; ADISASMITA, ASRI C
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Commonly hormonal drugs used by woman are contraceptive and hormone replacement therapy (HRT). A contraceptive user in Indonesia is about 62% aged 16-49 years, modern contraceptive users is 58%. Injected contraception user is 32% followed by oral contraceptive (pill) is 14%. Literature review conducted in this study. The risk use of both hormonal contraception and HRT causing breast cancer still have different opinion The researchers concluded that both of these factors affect the incidence of breast cancer.
Gambaran Computed Tomografi Scan Toraks Teratoma Kistik Paru NURBAETI, DETI; ICKSAN, AZIZA G; HIDAYAT, HERIAWATY
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Pulmonary cystic teratoma is a very rare disease, composed of tissues from more than one germ cell line. Pulmonary cystic teratoma commonly involve the upper lobe of the left lung, most follow a benign course and are incidental findings during routine chest X-rays. Proper diagnosis is needed to determine adequate treatment in order to reduce symptoms and improve quality of life. We report a twenty six years old man with clinical symptom hemoptysis, chest pain and dyspnea since one month before admission. The chest X-ray showed a large opacity of the entire right hemithorax, there is no calcification. On enhanced chest CT examination, we found an encapsulated cystic mass on the upper and middle of the right lung with peripheral enhancement. Histopathological examination confirmed an infected cyst with cystic teratoma. The main purpose of this report is to emphasize the importance of enhanced chest CT in evaluating patient suspected pulmonary cystic teratoma.
Akurasi Kadar Lysophosphatidic Acid Plasma dan Ca125 Serum Penderita Tumor Ovarium Jenis Epitel untuk Prediktor Keganasan Ovarium APRILIAWAN, TRI; ASKANDAR, BRAHMANA
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

This study was conducted to determine and compare the sensitivity, specificity, positive predictive value and negative predictive value between CA125, Lysophosphatidic Acid Plasma (LPA) and combination of LPA - CA125 in patients with ovarian mass.This study was a analytic observational cross sectional studies, with 56 subjects who had ovarian tumors, who had the inclusion and exclusion criteria research, in Department of Obstetrics and Gynecology FK-Unair/dr. Soetomo Hospital, Surabaya. After that, patients performed surgery, and histopatology examination of operation specimens in this hospital. Inclusion criteria for this study were patients with epithelial ovarian tumors from Anatomical Pathology examination. The 56 study subjects , we were divided into 2 groups based on histopatological examination, one group with 31 subjects we classified into epithelial type malignant ovarian tumors study group, while the other group consist of 25 subjects we classified into epithelial type benign ovarian tumors study group.Sensitivity, specificity, positive predictive value, negative predictive value of CA125 was 87.1%; 28%; 60%; and 63.8%. Sensitivity, specificity, positive predictive value, negative predictive value LPA was 51.6%; 76%; 72.7%; and 55,9%. And sensitivity, specificity, positive predictive value, negative predictive value combination LPA - CA125 was 45.2%; 92%; 87.5%; and 57.5%. And in this study we get the CA125 cut-off at 50 u/mL gives better results than 35 u/mL, whereas the LPA cut-off 2.5 ?M still the best, although the Kappa analysis results for both are not significant.In this study, plasma LPA level patients with ovarian tumor can not be used as a tumor marker for epithelial malignant ovarian cancer. CA125 levels can be used as a tumor marker for epithelial malignant ovarian cancer, while combination of CA125 levels and LPA levels increase the specificity but does not increase the sensitivity. This was contrast with previous studies that the sensitivity and specificity of plasma LPA is excellent and they proposed use LPA plasma as a tumor marker.
Mature Teratoma Intrapulmonary in Adolescent SIREGAR, OLGA RASIYANTI; LESTARI, WAHYUNINGSIH; ROSDIANA, NELLY
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Mature teratoma is the most common primary germ cell tumor in the mediastinum, but very rare in the lung. A very rare case of mature giant intrapulmonary teratoma in a 14 year old female is reported. She had chronic cough, recurrent fever, chest pain, weight loss and history of breathless for six months. A chest x-ray showed a large mass with atelectasis of the left lung and thoracic CT scan revealed a giant neoplasm of the left lung, sized about 13x19 cm with calcification. The patient underwent left thoracotomy posterolateral, the tumor was totally resected with pneumonectomy. The histopatological examination revealed a mature teratoma. Intrapulmonary teratoma is very rare tumors with nonspecific signs and symptoms. Total removal tumor is the treatment of choice for this type of teratoma.
Sistem Skoring Nefrometri R.E.N.A.L: Sistem Berstandar yang Komprehensif Dalam Menilai Ukuran, Lokasi, dan Kedalaman Tumor Ginjal REZA, MOCHAMMAD; RAKHMAN, ARIEF; MOCHTAR, CHAIDIR A
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

The treatment of localized renal cell carcinoma remains subjective.The R.E.N.A.L.- Nephrometry Score quantifies the characteristics of renal mass anatomy based on radiologic findings to provide a standardized objective descriptive system in an reproducible manner. We evaluate the utility of this system in predicting tumor resectability, operative approach and risk of complication, and their relevance to clinical practice.Electronic literature research was performed to access the main series of literature in the past 4 years since the scoring system developed. The articles were then analyzed and selected to address these issues. Fifteen peer-reviewed publications (2009 to 2012) were selected. Most of the studies were analyzed using the prospective acquired database. Increasing tumor complexity was asscociated with greater overall nephrometry score in patient underwent renal neprectomy and partial neprectomy. Compared with patients who underwent partial nephrectomy, the patients treated with radical nephrectomy had a significantly greater size (R), central proximity (N), and location (L) component scores. There were more complications among patients with higher R.E.N.A.L scores who underwent partial nechrectomy (PN) thanin patients with PN who did not developcomplications. The R.E.N.A.L nephrometry scoring system has good interobserver reliability showed by the similar sum of nephrometry score concordance to the R, E, N, A, and L components among surgeons in different centre. The R.E.N.A.L nephrometry standardize the reporting of solid renal masses and appears to effectively stratify the treatment choice for patients. Nephrometry aids in objectifying previously subjective measure and provide more meaningful comparison of treatment recommendation or results in published series.
A 21 Year-Old Male Colorectal Cancer Patient with Clostridium Difficile and Intestinal Amebiasis Infection LUGITO, NATA PRATAMA HARDJO; -, SUSANTI; KURNIAWAN, ANDREE
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was associated with several bacterial and viral infections like Streptococcus bovis, Helicobacter pylori, human papilloma virus, and Clostridium septicum. Here we report a case of Clostridium difficile and Entamoeba histolytica infection in young adult male patient with colorectal cancer. The patient presented with chronic bloody diarrhea since one year prior to diagnosis with histories of antibiotics but no hospitalization, surgery or chemotherapy.

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