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INDONESIA
INDONESIAN JOURNAL OF PHARMACY
Published by Universitas Gadjah Mada
ISSN : 23389427     EISSN : 23389486     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas Gadjah Mada (UGM) Yogyakarta Indonesia in collaboration with IAI (Ikatan Apoteker Indonesia or Indonesian Pharmacist Association) and only receives manuscripts in English. Indonesian Journal of Pharmacy is Accredited by Directorate General of Higher Education (DGHE) DIKTI No. 58/DIKTI/Kep/2013.
Arjuna Subject : -
Articles 2 Documents
 1 
Search results for , issue " Vol 17 No 3, 2006" : 2 Documents clear
Cost analysis of Diabetes mellitus therapy in Dr. Sardjito Hospital Yogyakarta Aisyah, Tri Murti
INDONESIAN JOURNAL OF PHARMACY Vol 17 No 3, 2006
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.776 KB) | DOI: 10.14499/indonesianjpharm0iss0pp130-135

Abstract

Diabetes mellitus is a chronic disorder that has been recognized by Indonesian government as a major public health problem with far reaching consequences not just for its adverse impact on the health of Indonesian, but also for the economic burden it places on the health care systems. The objective of this study was to describe the therapeutic cost of outpatient diabetes mellitus type 2.A descriptive study was performed on patient who were admitted to the Department of Endocrinology of the Sardjito Hospital between July and August 2005. Patient were included if they were ambulatory during the time of the study. Exclusion criteria were patients with any other diseases. Only direct medical cost was considered (perspective from hospital). Direct costs to this analysis were cost of drugs, visit to the physician, laboratory examinations, and cost of diabetes-related complications and concomitant therapies.From the 100 examined patients, 44 percent were females and 56 percent were males. The average age of the patients was 60.75 ranging from 41 to 85 years of age. The average total costs per patient per month was Rp 208,500 with a maximum to be Rp 754,500. The largest cost was drug acquisition costs (59.5%), followed by cost of diabetes-related complications (31%). The control of blood glucose using combination therapy was more frequently attained in patients taking sulfonylurea and biguanid (44.62%). The combination of biguanid, α-glucosidase inhibitor, and insulin had the greatest expense, equal to Rp.571,000. Hypertension, neuropathy, and hyperlipidemia were the most frequently mentioned complications diseases. The cost for diabetes-related complication included hypertension and retinopathy had the greatest expense, equals to Rp 754,500.Key words: cost-identification, diabetes mellitus, Dr. Sardjito hospital
Three resveratrol’s oligomers from the stem bark of H. gregaria (dipterocarpaceae) and their toxicity and citotoxicity ., Sahidin; Hakim, Euis H.; Syah, Yana M.; Juliawaty, Lia D.; Achmad, Sjamsul A.; Latip, Jalifah
INDONESIAN JOURNAL OF PHARMACY Vol 17 No 3, 2006
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.948 KB) | DOI: 10.14499/indonesianjpharm0iss0pp109-115

Abstract

Three resveratrol oligomers have been isolated from the stem bark of H. gregaria including a resveratrol trimer i.e. α-viniferin (1), and two resveratrol tetramers i.e. vaticanol B (2) and hopeaphenol (3). These structures were determined by spectroscopic evidence including UV, IR, 1H , 13C NMR and compared with that of the reported data in the literatures. Activities of the compounds were determined toward brine shrimp Artemia salina (toxicity) and murine leukemia P-388 cells (cytotoxicity). The compound 1 is the most active against A. salina (LC50 = 49,0 ± 5,8 μg/mL), and the compound 3 has very active level toward murine leukemia P-388 cells (LC50 = 5,7 ± 0,3 μM).Key words : Resveratrol oligomers, H. gregaria, toxicity, and cytotoxicity.

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