Articles
10 Documents
Search results for
, issue
"Vol 43 No 3 (2012): September 2012"
:
10 Documents
clear
<![CDATA[REDUCTION OF NUTRIENT STATUS NASOPHARYNGEAL CANCER PATIENTS AFTER RADIOTHERAPY WITH COBALT - 60 IN SANGLAH HOSPITAL ]]>
<![CDATA[Sudiasa, Putu]]>;
<![CDATA[Tjekeg, Made]]>;
<![CDATA[Puteri, AA Sagung Puteri]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (190.11 KB)
<![CDATA[Nowadays radioterapy is still a standard treatment for nasopharyngeal cancer. Treatment with radiotherapy and or chemotherapy can effect the nutrient status of patients. Body Mass Index ( BMI ) is an indicator of a nutrient status measurement. BMI is expressed as body weight in kilograms divided by height squared in meters size. The objective of this study is to define the alteration of nutrient status in nasopharyngeal cancer patients with who underwent radiotherapy with Cobalt -60. With pre-post test single group method. The result showed significant decrease (P<0,05) of body weight a[er radiotherapy, i.e from 59.01 (SD 14.30) kg to 52.51 (SD 14.24) kg. Body mass index (BMI) prior to radiotherapy 22.42 ( SD 4.35 ) kg/m2 and a[er radiotherapy 19.89 ( SD 4,23) kg/m2. It was concluded that there is a significant nutrient status reduction in nasopharyngeal cancer patients a[er radiotherapy with Cobalt-60]]>
<![CDATA[RELATIONSHIP OF URINARY C-TERMINAL TELOPEPTIDE COLLAGEN TYPE-II (CTX-II) LEVEL WITH THE DEGREE OF JOINT DAMAGE IN PATIENTS WITH KNEE OSTEOARTHITIS ]]>
<![CDATA[Handono, Kusworini]]>;
<![CDATA[**, Farida]]>;
<![CDATA[Suryana, BP Putra]]>;
<![CDATA[Listyawati, Enny]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (266.406 KB)
<![CDATA[Radiography of the knee is used to confirm the diagnosis and classification of knee OA severity. Urinary CTX- II is a biochemical marker for assessing cartilage degradation of knee OA. This research aimed to analyze the correlation between the level of urinary CTX-II and the radiographic severity of knee OA. Research was conducted in 40 patients with knee OA ( ACR criteria ) and 40 age and sex matched healthy controls. Wheight bearing anteroposterior and lateral semiflexed radiographs were taken of both knee. The patients were stratified based on the Kellgreen-Lawrence (K-L) score. Urinary CTX-II level was measured using ELISA competitive method. Correlation between urinary CTX-II level and radiographic knee OA severity was analyzed with Spearman Correlation. Statistical significance level at P < 0.05. Mean urinary CTX-II level was significantly higher in patients with OA compared with healthy controls (447.7( SB 316.39) ng/ml vs 289(SB 168.01) ng/mmol respectively, P = 0.023). There was a significant difference between urinary CTX-II level in patients with grade ? 2 K-L knee OA compared with patients with grade > 2 K-L (240.35 (SB 88.90) ng/mmol vs 728.24 (SB 295.15) ng/mmol respectively; P < 0.001). The urinary CTX-II level was significantly associated with the degree of joint lesion in patients with OA (r = 0.734; P = 0.0001). Urinary level of CTX-II is strongly associated with the degree of radiographic joint lesion of OA]]>
<![CDATA[THE CHARACTERISTIC OF CYTOLOGICAL AND PCR TESTS RESULT OF FINE NEEDLE ASPIRATION (FNA) SPECIMEN FROM NECK LYMPH NODE/S ENLARGEMENT CLINICALLY DIAGNOSED AS TUBERCULOUS LYMPH ADENITIS ]]>
<![CDATA[Winarti, Ni Wayan]]>;
<![CDATA[Sriwidyani, Ni Putu]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (380.303 KB)
<![CDATA[Diagnosis of Tuberculous (TB) lymph adenitis is still problematic due to paucibacillar. Since histopathological biopsy examination is relatively expensive and needs times, FNA is being more frequently chosen. The specimen from FNA can be processed for cytological and PCR tests, but there is no data available describe the characteristic of the result of both methods. Hence, study is needed in order to improve knowledge and health services. A cross sectional study had been conducted from January 1st until December 31st , 2011, at Anatomical Pathology Laboratory of Medical School of Udayana University/Sanglah Hospital and Biomolecular Laboratory of Medical School of Udayana University. The subjects were all patients with clinical diagnosis TB lymph adenitis who met the eligibility criteria. During 6 months, there were 46 patients included in the study. They were 65% female and 35% male. The age was ranging from 5 years old until 83 years old and 30-39 years old age group was the highest in number (39%). Positive cytology result was found in 22 cases (48%), while PCR test revealed no positive result. There was significant diference between positive and negative cytology test in pain sensation category, conversely in onset, number of enlarged lymph node/s, localization, conglomeration and fixation categories. If every single clinical character was marked with score 1, node/s with accumulative scores 4-6 showed no different cytology result with node/s with score 1-3. This study shows that in detecting TB lymph adenitis using FNA specimen, cytology test was be#er than PCR]]>
<![CDATA[THE ROLE OF GROWTH HORMONE IN LIPID METABOLISM ]]>
<![CDATA[Dewi Ratnayanti, I Gusti Ayu]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (311.082 KB)
<![CDATA[Growth hormone (GH) is one of the hormones that regulate metabolism, including lipid metabolism. GH can regulate the amount of fat in the tissue and also the level of lipid profile. Growth hormone affects the lipid in the tissue and blood by modulating the lipid metabolism, especially through the regulation of synthesis, excretion and breakdown of internal lipids. Research showed that GH could consistently lower the level of total cholesterol and LDL, whereas its effect on triglyceride and HDL level showed varying results. Growth hormone induces lypolisis by stimulating the activity of HSL and LPL and thereby influenced the triglyceride level and tissue fat storage. Cholesterol and lipoprotein levels are controlled by regulating the synthesis of cholesterol by lowering the activity of HMGCoA reductase. The excretion of cholesterol through the bile is also enhanced by stimulating the activity of enzymes C7?OH. The breakdown of VLDL and LDL are enhanced by increasing the expression of LDL receptor and ApoE as well as affecting the editing of mRNA ApoB100. Increase activity of LPL is also known to be the important factor in the HDL metabolism]]>
<![CDATA[IDENTIFICATION OF G10398A VARIAN OF ND3 GENE MITHOCONDRIA DNA IN BREAST CANCER PATIENT ]]>
<![CDATA[Tianing, Ni Wayan]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (1005.644 KB)
<![CDATA[ND3 gene is a mitochondria DNA gene which code for NADH dehydrogenase enzime, part of complex 1 respiratory chain oxidation and involved in phosphorilation prosess to synthesize ATP (Adenosin Triphosphat). The present of G10398A variant at mtDNA result in changing the amino acid code for alanine (GCC) to threonine (ACC). This changing induce elevation the ROS (Reactive Oxygen Species) concentration in mitochondria. ROS can cause oxidation of DNA, mutation of DNA,oxidative stress and cancer. The other effect of ROS can affect redox-cycling estrogen metabolism. Individual with G10398A variant has 60% risk for breast cancer. The purpose of this research are to identify G10398A variant and its proportion in ND3 gene with non experimental descriptive method within 32 samples and 5 control. This research has done with sequence of steps with an isolation and total DNA amplification electrophoresis, sequencing and analysis by comparing with gene bank. This research identify G10399A variant that causes changing code from serine (AGC) amino acid in to asparagines (AAC) in 16 samples. Another variant found in this research is C10401T variant the cause changing in codon that code from arginin (CGA) in to triptopan (TGA) within 14 samples. In the control groups 2 samples identify with G10399A variant, 2 samples with C10401T and 1 control match like gene-bank. For this research, ND3 gene homology that was amplified found in the average of 96%.]]>
<![CDATA[THE ROLE OF MECHANOTRANSDUCTION IN OSTEOPOROSIS PATOPHYSIOLOGY ]]>
<![CDATA[**, Yuliana]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (376.403 KB)
<![CDATA[Osteoporosis is o[en encountered by elderly people. It can cause fracture. This disease can be prevented by doing physical activity. Osteocyte as mechanosensory cell, has important role in mechanotransduction system. There are four anabolic transduction signals, i.e. Wnt pathway, BMP/transforming growth factor (TGF)-pathway, ER pathway, and growth hormone/insulin-like growth Factor (IGF)-I pathway. Any disorder on mechanotransduction system will cause osteoporosis.]]>
<![CDATA[ZINC SERUM LEVEL AND PERIPHERAL BLOOD MONOCYTE COUNT OF MULTIBACILAR LEPROSY PATIENT LOWER THAN PAUCIBACILAR LEPROSY IN RSUP SANGLAH ]]>
<![CDATA[Kurniawan Dhana, Putu]]>;
<![CDATA[Darma Putra, IGN]]>;
<![CDATA[Wardhana, Made]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (196.878 KB)
<![CDATA[Zinc has been known to have important role in the immune system. Zinc deficiency can inhibit activation and production cytokine of Th1 and may cause cellular immunity dysfunction. This conditon also may cause changes of lymphopoiesis and hematopoiesis also peripheral blood of mononuclear cell as mononuclear fagocyte. The Aim of this study is to know zinc serum status and peripheral blood monocyte count of leprosy patient in Dermato Venerologi policlinic Sanglah hospital Denpasar. This study use cross sectional design. Sample of study take by consecutive sampling with sample size contains 75 patient. Mean of zinc serum status on multibacillary leprosy patient is 5.66 (SB 11.74 ) found lower compare to paucibacillary leprosy patient 19.38 (SB 18.21) and statistically significant with P < 0.05. Mean of peripheral blood monocyte count in multibacillary patient is 7.12 (SB 2.53) lower compare to paucibacillary leprosy patient with 7.88 (SB 3.08), but statistically not significant with P > 0.05. Binary logistic analysis show the influence of zinc serum status to probability to have leprosy. This study suggest correction of serum zinc level in leprosy patient through nutritional approach or the granting of a supplement of zinc]]>
<![CDATA[SPONTANEOUS PNEUMOPERITONEUM IN A SEVEN DAY OLD INFANT ]]>
<![CDATA[Luhulima, Franky]]>;
<![CDATA[Kardana, Made]]>;
<![CDATA[Artana, IW Dharma]]>;
<![CDATA[Junara, Putu]]>;
<![CDATA[Dharmajaya, IM]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (526.515 KB)
<![CDATA[The term pneumoperitoneum is used to describe the presence of free gas or air within the peritoneal cavity. Spontaneous pneumoperitoneum or “non-surgical” pneumoperitoneum is a pneumoperitoneum. not associated with a perforated viscus. This pneumoperitoneum is rare at any pediatric age. In the pediatric population, nonsurgical pneumoperitoneum occurs in 1% to 3% of mechanically ventilated infants, depend on the mode of the ventilation. Pneumoperitoneum without gastrointestinal perforation on the other hand is very rare, and this is usually seen in neonates with respiratory distress and on mechanically ventilator or CPAP. We reported a case of spontaneous pneumoperitoneum in a seven day old infant . The infant presented with a sudden abdominal distention and dyspnea. Plain abdominal x-ray showed a radiolucency image in the superior abdomen. In this patient is done the act of a needle aspirations for drainage air in the peritonium. This patient recovered well a[er done such action by pediatric surgical]]>
<![CDATA[ORALLY LACTATE CALCIUM AND SWIMMING DECREASE OSTEOCLAST AND INCREASE OSTEOBLAST IN RADIAL PERIMENOPAUSAL MICE (MUS MUSCULUS) BONE ]]>
<![CDATA[**, Muliani]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (810.197 KB)
<![CDATA[Calcium and moderate intensity swimming exercise can increase bone density. The aim of this research is to see the effect of orally calcium consumption and swimming activity to decrease osteoclast and increase osteoblast in radial perimenopausal mice (Mus musculus) bone. Pretest and pos#est control group design was used in this research. Research subject used 15-16 aged mice (Mus musculus) which divided into 4 groups (each group consisted of 13 mice), that was control, lactate calcium, swimming and lactate calcium and swimming. Treatment was given 90 days. This study showed a significant difference of the mean of the pos#est osteoblast between control and experimental groups (P<0.05). There was no significant difference between lactate calcium and swimming groups (P>0.05). Enhancement of osteoblast mean in combination group was greater than the other experimental groups. There was a significant difference of the mean of the pos#est osteoclast between control and experimental groups (P<0.05), without significant difference between lactate calcium, swimming groups and combination of lactate calcium and swimming group (P>0.05). Conclusion: either lactate calcium or swimming decreases osteoclast and increases osteoblast of the mice but the osteoblast enhancement will be bigger when they are given together at once]]>
<![CDATA[ADMINISTRATION OF CACAO BEANS (Theobroma cacao L.) EXTRACTS DECREASE MALONDIALDEHYDE CONCENTRATION AND INCREASE BLOOD NOx CONCENTRATION IN WHITE RAT (Ra"us norvegicus) INDUCED BY PSYCHOSOCIAL STRESS ]]>
<![CDATA[IA, Dewi Wiryanthini]]>;
<![CDATA[IGM, Aman]]>;
<![CDATA[NA, Bagiada]]>
<![CDATA[ Medicina Vol 43 No 3 (2012): September 2012 ]]>
Publisher : <![CDATA[Medicina ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (285.815 KB)
<![CDATA[Increased production of reactive oxygen species (ROS) causing accumulation of oxidative damage caused by exceeding anti oxidant capacity in the body. Psychological stress as psychosocial stress can induce oxidative stress which subsequently cause increase blood malondialdehyde (MDA) and decrease blood nitrate and nitrite (NOx) concentration as intermediate product of nitric oxide (NO). Cacao beans extracts contained anti oxidant flavanols consist of catechin, epicatechin and procyanidin. The aims of this study is to investigate the effect of cacao beans (Theobroma cacao L.) extracts for decreasing MDA and increasing NOx concentration in white rat (Ra$us norvegicus) blood in stress oxidative state induced by psychosocial stress. It is an experimental study with Pretest-Postest Control Group Design. This study revealed decrease MDA concentration in group P1 (11.47 vs 8.04), P2 (11.92 vs 5.44) and P3 (11.69 vs 2.87) with P = 0.000 and increase NOx concentration in oxidative stress white rat induced by psychosocial stress a[er administration of cacao beans extract in group P1 (1909.83 vs 2085.16), P2 (1912.5 vs 2231.83) and P3 (1871.5 vs 2339.83) with P = 0.005. This study showed that cacao beans extract can inhibit oxidative stress caused by psychosocial stress.]]>
