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INDONESIA
Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 23 Documents
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Search results for , issue "Vol 11, No 2 (2015)" : 23 Documents clear
DERAJAT INFILTRASI LIMFOSIT PADA PENDERITA KANKER KOLOREKTAL SUB-TIPE ADENOKARSINOMA Muhammad Sahal Imaduddin; Ika Kustiyah Oktaviyanti; Istiana Istiana
Berkala Kedokteran Vol 11, No 2 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.136 KB) | DOI: 10.20527/jbk.v11i2.141

Abstract

Cancer is the second leading cause of death which contributes 13% of deaths from a total of 22% of deaths from non-communicable diseases in the world. One contributor to the number of cancer deaths in the world is colorectal cancer. The prognosis of colorectal cancer depend on the stage of cancer at time of diagnosis. However, the prognosis of colorectal cancer can also be determined by looking at the degree of infiltration of lymphocytes in cancer. The purpose of this research is to find out the degree of lymphocytes infiltration in patients with colorectal cancer in Laboratory of Anatomical Pathology Banjarmasin from January to December 2013. The method uses descriptive research by observing the colorectal cancer tissues were obtained from the Laboratory of Pathology Banjarmasin. From a study of 32 samples, found the degree of mild lymphocytic infiltration occurred in 12 patients (37.5%), moderate lymphocytic infiltration occurred in 12 patients (37.5%), and severe lymphocyte infiltration occurred in 8 patients (25%). From this study, found that there are differences in the degree of infiltration of lymphocytes in patients with colorectal cancer. Keywords: Colorectal Cancer, Lymphocyte Infiltration, Prognosis
POTENSI BUAH NANGKA (Artocarpus heterophyllus L) SEBAGAI ANTIDIABETES IN VITRO Khairina Khairina; Eko Suhartono; Agung Biworo
Berkala Kedokteran Vol 11, No 2 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.491 KB) | DOI: 10.20527/jbk.v11i2.142

Abstract

Artocarpus species have been used by traditional medicine of Indonesian. It can be useful as anti-bacterial, anti-diabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to test the inhibitory glycated hemoglobin potency of aqueous extract of Jackfuit. This study is a quasi experimental research with non randomized method post test-only group design, which using a model reaction of two groups : extract jackfruit as the test group and glikazid as the control group, with each concentration of 10%, 20%, 30%. Potential inhibitor of glycated hemoglobin jackfruit as determining the amount of IC50. From this research  got IC50 of jackfruit extracts is 56,43% (r=0,999) whereas for glikazid of 17.268 (r = 0.989). The value of r indicates a positive relationship between the concentration and the inhibitor glycated hemoglobin potential. These results indicate that the extract of Jackfruit has potential as an inhibitor glycated hemoglobin. Keywords: glycated hemoglobin,  jackfruit, Artocarpus heterophllus L, glikazid.
KADAR TESTOSTERON INTRATESTIKULAR TIKUS Rattus novergicus STRAIN Sprague dawley AKIBAT PEMBERIAN KURKUMIN SETELAH STIMULASI hCG Husnul Khatimah
Berkala Kedokteran Vol 11, No 2 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.491 KB) | DOI: 10.20527/jbk.v11i2.168

Abstract

Curcumin is an active agent on Curcuma longa. Curcumin had so many biologic activities; one of them is anti fertility. Curcumin research in male reproductive system had been done. Curcumin reduced testis weight and serum testosterone. This study is done to know curcumin effect on testosterone intratesticular level in rats. This study was conducted to 15 male Sprague dawley rats aged 90 days. Rats divided into 5 groups treatment : group 1 rats were given aquades, group 2 rats were given a single dose of 50 IU hCG, group 3 rats were given CMC, group 4 rats were given curcumin, group 5 rats were given hCG and curcumin.  Rats were sacrified on age 91 days. Testis was taken, homogenizer and sentrifuge. Supernatant was taken in order to measured intratesticular testosterone level. The result of this study show intratesticular testosterone level from 5 group treatment, each group are n = 3, are (1) 44.36±1.30 (aquades), (2) 41.53±16.44 (hCG), (3) 37.33±9.05 (CMC), (4) 54.16±29.82 (curcumin), (5) 49.36±5.05 (hCG + curcuminStatistic analytic with ANOVA showed there is no significant difference  (p>0.05). This study had a conclusion that curcumin not decreased testosterone intratestikular level in rats. Keywords: curcumin, hCG, intratesticular testosterone

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