Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

MNJ (Malang Neurology Journal)

MNJ
Website

Published by Universitas Brawijaya

ISSN : 24076724 EISSN : 24425001 DOI : -

Core Subject : Science,

Neuroscience

Malang Neurology Journal is a peer-reviewed and open access journal that focuses on promoting neurological sciences generated from basic neurosciences and clinical neurology. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures of neurology disease, treatment, or other health issues related to neurology that is important also acceptable. Letters and commentaries of our published articles are welcome.

Arjuna Subject : -

Articles 7 Documents

Search results for , issue "Vol 4, No 1 (2018): January" : 7 Documents clear

VACCINE FOR NEUROCYSTICERCOSIS: A PRESENT UPDATE Wiwanitkit, Viroj
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Cysticercosis is an important tropical parasitic worm infestation. This infection can result in cyst in any organs of human beings including to brain. The brain involvement of cysticercosis or neurocyticercosis is an important neurological infection that can cause serious neuruological problem. A good sanitation is the basic prevention for cysticercosis. Nevertheless, the hope is the use of vaccination. Here, the author briefly reviews and discusses on the present situation of neurocysticercosis vaccine.

LEVELSâ€™ INFLUENCE OF IFN-Î³ AND IL-10 IN CHILDREN WITH EPILEPTICUS STATUS Salim, Irfan Agus; Muid, Masdar; Sujuti, Hidayat
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Background. Seizures are a common clinical manifestation in the emergency room. Nearly 5% of children aged under 16 years. Seizures are important as a sign of neurological disorders. Members of interferon are widely studied with seizures and epileptogenesis is interferon-Î³. In a study by Choi in 2011, a study of seizures in humans showed that the condition of status epilepticus increased levels of interferon-Î³ which is quite high compared to patients not status epilepticus seizures. In response to the aftermath of the seizure, Interferon-Î³ system induces the formation of IL-10 acts as an anti-inflammatory agent that aims to put an end to the action of Interferon-Î³. Objective. To know role of Interferon-Î³ and IL-10 in children with status epilepticus.Methods. This research using cross sectional design with recruiting 30 study sample consisted of 15 children in the seizure group SE and 15 children in the group without SE seizures. Measured levels of IFN-Î³ and interleukin-10 by ELISA. Results were analyzed with the Mann-Whitney and corelation Spearman to see the relationship levels of IFN-Î³ and IL-10 in children with status epilepticus with SPSS-23.Results. The results showed significant differences between groups SE and convulsive seizures non SE ;IL10 (p = 0.000) and IFN-Î³ (p= 000).Conclusion. There areÂ significantÂ correlationÂ betweenÂ theÂ levelsÂ ofÂ IFN-Î³Â andÂ IL-10 with statusÂ epilepticus.Â

THE CORRELATION OF WAIST HIP RATIO TO ISCHEMIC STROKE PROBABILITY OF POPULATION IN SEKARBELA MATARAM Setiadi, Qisthinadia Hazhiyah; Harahap, Herpan Syafii; Indrayana, Yanna
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Background. Stroke is the third cause of death worldwide. Ischemic stroke is the most common type of stroke with high prevalence. Obesity is one of ischemic stroke risk factor, but its correlation with higher ischemic stroke risk remains unclear. Studies about correlation of waist hip ratio (WHR) and ischemic stroke risk is still contradictive. Objective. This study was aimed to explore the correlation between WHR and ischemic stroke probability.Methods. This was a descriptive analytic study using cross sectional design. The population of this study was resident in Sekarbela Mataram aged 55-84 years old. This study was conducted 63 participants. They were interviewed and received a measurement of WHR and ischemic stroke probability. The ischemicstroke probability was assessed by using assessment of Framingham stroke risk score. Data were analyzed by using Pearson correlation.Results. Among 63 participants, 51 (81%) were abdominal obesity and 12 (19%) were normal based on WHR measurement. Pearson correlation analysis showed that there was no correlation between WHR and ischemic stroke probability (p = 0,11).Conclusion. There was no correlation between WHR and ischemic stroke probability of population in Sekarbela Mataram

BIOMOLECULAR MECHANISM OF ANTI EPILEPTIC DRUGS Husna, Machlusil; Kurniawan, Shahdevi Nandar
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Epilepsy therapy is almost always chronic and often used more than one drug. Currently, antiepileptic drugs are still the mainstay of therapy for epilepsy. An understanding of the pharmacodynamics and pharmacokinetics of these drugs would be very helpful in choosing the right medication and develop a study to determine the drugs mechanism further. Mechanism of action of AED (anti epileptic drug) can be categorized into four main groups: (1) modulation of voltage-gated ion channels, including sodium, calcium, and potassium; (2) increase in GABA inhibition through an effect on GABA-A receptors, the GAT-1 GABA transporter, or GABA transaminase; (3) direct modulation of the synaptic release of such SV2A and Î±2Î´; and (4) inhibition of excitatory synapses through ionotropik glutamate receptors including AMPA receptors. AED work to balance the process of inhibition and excitation in the brain, so it can be used both for epilepsy and other diseases with similarities with the pathophysiology of epilepsy.

EFFECTS OF GENISTEIN EXPOSURE TOWARD INITIAL DEVELOPMENT OF CENTRAL NERVOUS SYSTEM IN CHICKEN EMBRYO MODEL (GALLUS GALLUS) AGE 48 HOURS Rahayu, Indriati Dwi; Paundralingga, Obed Trinurcahyo Kinantyo; Sari, Vidia Purnama
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Background. The safety of genistein consumption in the first trimester of pregnancy and its effect on embryonic development, especially in the development of Central Nervous System (CNS) is still not widely known.Objective. To determine the effect of genistein exposure to the early development of the Central Nervous System.Methods. The animal model used in this research is chick embryo (Gallus gallus). Genistein at a dose of 5 ÂµM, 10 ÂµM and 20 ÂµM in ovo injected into the yolk sac of the eggs before incubation. The eggs were then incubated for 48 hours at a temperature of from 37.50 to 38.50 C. After 48 hours, broken egg shell, embryos are taken and carried out using Toluidine Blue staining. The evaluation was done on the neural tube, anterior neuropore, posterior neuropore and somites.Results. It was found neural tube defects in the group treated with genistein more than the control group but the result was not statistically significant.Conclusion. For the somites, in the group treated with a dose of 10 ÂµM genistein, the number of somites more than the control group and statistically the number is significant.

AMPLITUDO SENSORY NEURON ACTION POTENTIAL USING AS INSTALLATION OF POLYNEUROPATHY DIAGNOSIS Kinesya, Billi; Husna, Machlusil; Kurniawan, Shahdevi Nandar; Ridwan, Mochammad
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Background. Polyneuropathy is the pathologic changes and functional disturbances in the peripheral nervous system. These changes manifest as sign and symptoms such as numbness, burning, allodynia, atrophy, and lose of stimulation responses. Diagnosing polyneuropathy can use electrodiagnostic method like electroneuromyography (ENMG). One of the most sensitive ENMG parameters for polyneuropathy is SNAP amplitude which can be measured at Sural Nerve.Objective. The goal of this study is to know whether SNAP amplitude can be used to diagnose polyneuropathy.Methods. The study design is diagnostic test in cross-sectional method.Results. Samples were taken from 108 ENMG medical records of Neurology Department Saiful Anwar General Hospital during the whole 2014. Two variables which are compared are polyneuropathy diagnosis and SNAP amplitude. Fisher test shows significant differences between the two with p = 0.04. Diagnostic test shows sensitivity 68.3%, spesifisity 80%, positive predictive value 97.1%, and negative predictive value 20.5%.Conclusion. There is a significant relationship between SNAP amplitude reduction with the diagnosis of polyneuropathy.

DIAGNOSTIC TEST OF TORONTO AND MODIFIED TORONTO SCORING, MONOFILAMENT TEST, AND VIBRATE SENSATION TEST USING 128 HZ TUNING FORK FOR DIABETIC POLYNEUROPATHY Purbasari, Bethasiwi; Anggraini, Vivi Laras; Pratiwi, Made Dinda; Husna, Machlusil; Kurniawan, Shahdevi Nandar
Malang Neurology Journal Vol 4, No 1 (2018): January
Publisher : Malang Neurology Journal

Background. The prevalence of diabetes mellitus has been epidemically increasing throughout all the world population, and diabetic polyneuropathy (PNP-DM) is one of the most common neurologic manifestation of this disease. Clinical research has proved that effective bedside screening of PNP-DM can significantly reduce the incidence of foot ulcer and limb amputation. Objective. To measure the diagnostic test of polyneuropathy scoring, monofilament 10-g SemmesWeinsteinÂ test, and 128 Hz tuning fork test as an early detection measure for PNP-DM.Methods. This research was conducted using a cross sectional approach from Januari 2016 to Juli 2017.Results. Among the total study population of 43 (23 men and 20 woman), Modified Toronto Score has the highest sensitivity (100%), PPV (93%) and accuracy (93%). Toronto score has the highest NPV (9%).Conclusion. Modified Toronto Score has good diagnostic value as screening tool in PNP-DM.

Page 1 of 1 | Total Record : 7

Filter by Year

2018 2018

Filter By Issues

All Issue Vol. 11 No. 2 (2025): July Vol. 11 No. 1 (2025): January Vol. 10 No. 2 (2024): July Vol. 10 No. 1 (2024): January Vol. 9 No. 2 (2023): July Vol. 9 No. 1 (2023): January Vol. 8 No. 2 (2022): July Vol. 8 No. 1 (2022): January Vol. 7 No. 2 (2021): July Vol. 7 No. 1 (2021): January Vol. 6 No. 2 (2020): July Vol 6, No 1 (2020): January Vol 5, No 2 (2019): July Vol 5, No 1 (2019): January Vol 5, No 1 (2019): January Vol 4, No 2 (2018): July Vol 4, No 1 (2018): January Vol 4, No 1 (2018): January Vol 3, No 2 (2017): July Vol 3, No 1 (2017): January Vol 2, No 2 (2016): July Vol 2, No 2 (2016): July Vol 2, No 1 (2016): January Vol 2, No 1 (2016): January Vol 1, No 2 (2015): July Vol 1, No 1 (2015): January More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota malang,

Jawa timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota malang, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota malang,

Jawa timur

INDONESIA