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INDONESIA
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES
Published by Universitas Udayana
ISSN : 20854773     EISSN : 23022906     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesia Journal of Biomedical Science (IJBS), Print-ISSN 2085-4773; E-ISSN 2302-2906 is an international and peer-reviewed journal published twice per year in print and online by Indonesian of Biomedical Association in collaboration to Postgraduate School of Biomedicine Udayana University, Bali-Indonesia which was founded in 2007. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of biomedical scholarship, and to encourage a vigorous dialogue between biomedical scholars and researches. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and biomedical researchers all over the world.
Arjuna Subject : -
Articles 2 Documents
 1 
Search results for , issue "Vol 8 No 1 (2014): IJBS Vol8 No1" : 2 Documents clear
ANTI-HIPERCHOLESTEROLEMIA OF ANREDERA CORDIFOLIA IN HYPERCHOLESTEROLEMIA RAT WISTAR THROUGH DECREASE OF MALONDIALDEHYDE AND 8-HYDROXY-DIGUANOSINE Wahjuni, S.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 8 No 1 (2014): IJBS Vol8 No1
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.183 KB)

Abstract

High cholesterol diet leads to increase of plasma cholesterol and subsequently will end up with hypercholesterolemia. Ignorance of healthy food and lacks of activity are the trend of modern life style. These conditions exacerbated the incidence of hypercholesterolemia in either developed or developing countries. This research aims to determine potential of anredera cordifolia leafs extracts as an anti-hypercholesterolemia by lowering of malondialdehyde (MDA) and 8-hydroxy-diguanosine (8-OHdG) blood levels in hypercholesterolemia Wistar Rat. This is an experimental study applied post only control group design. A number of 15 male wistar rats were used in this study. Rats were randomly divided into 3 groups, i.e. negative control group (C1), positive control group (C2) and anredera cordifolia leaf extract at dose of 100 mg/kg BW group (T). MDA was determined based on malondialdehyde assay (NWLSSTM).  8-OHdG was determined based on oxidative DNA Damage (Cell Biolabs, Inc). The mean difference between control and treatment was assessed by applying ANOVA and consider significant at p < 0.05. In this study, we observed that there were a significant of MDA and 8-OHdG levels between group C1 and T; C2 and T within p < 0.05. This result indicates anredera cordifolia leafs extract has an ability to inhibit hypercholesterolemia in wistar rat fed with high cholesterol diet.
THE INCREASED INCIDENCE OF NAUSEA AND VOMITING DUE TO ANXIETY IN PACLITAXEL CARBOPLATIN CHEMOTHERAPY IN A 48 YEARS OLD FEMALE PATIENT WITH CERVICAL CANCER: A Case Report Putra, I. F. W.; Noviyani, R.; Suwiyoga, and, K.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 8 No 1 (2014): IJBS Vol8 No1
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.322 KB)

Abstract

Nausea and vomiting was the frequently side effects in chemotherapy.Uncontrolled nausea and vomiting can cause weakened body condition, reduced appetite and drinking, dehydration, electrolyte disturbances, reduced nutritional status so the patient refused to undergo further chemotherapy. Anxiety is one of the factors that increase the risk of nausea and vomiting. We reported the case of the woman 48 years old, height 150 cm, weight 51 kg, occupation housewife, diagnosed non-keratinizing squamous cell carcinoma cervical cancer  stage-IIB and received paclitaxel carboplatin for three cycles of chemotherapy. She experienced anxiety, acute nausea vomiting on the third cycle of chemotherapy and delayed nausea and vomiting of the three cycles of chemotherapy.

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