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Padjadjaran Journal of Dentistry
Published by Universitas Padjadjaran
ISSN : 19790201     EISSN : 25496212     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Padjadjaran Journal of Dentistry or known as PJD, is an English-language scientific periodicals published by the Faculty of Dentistry Universitas Padjadjaran thrice a year on every March, July and November. The submission process of manuscript is open throughout the year. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication. Designed as a medium of information and scientific knowledge, Padjadjaran Journal of Dentistry publishes numerous research articles, in the area of Oral Biology, Dental Material Science and Technology, Oral and Maxillofacial Surgery, Pedodontics, Dental Public Health and Community Dentistry, Conservative Dentistry, Periodontics, Prosthodontics, Orthodontics, Oral Medicine, Dental Radiology, as well as with their development through interdisciplinary and multidisciplinary approach. Initially published as Padjadjaran Journal of Dentistry (PJD) magazine ISSN 1979-0201(print) on 2007 in form of printed issues. In 2017, the magazine had its online published version under the same with ISSN 2549-6212 (online) in accordance with the policy of LIPI. Padjadjaran Journal of Dentistry has been using Open Journal System requiring all writers to register in advance before they are allowed to upload the manuscript they write online. Afterwards, the editors, peer reviewers, and writers can monitor the manuscript processing. Several other changes are informed in the Journal History.
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Articles 11 Documents
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Search results for , issue " Vol 21, No 2 (2009): July" : 11 Documents clear
The effect of apple (Malus Domestica) juice on the damage of mice liver cells due to paracetamol treatment Hartanto, Anthony; Dardjan, Murnisari; Kintawati, Silvi
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.675 KB) | DOI: 10.24198/pjd.vol21no2.14095

Abstract

The liver is an important organ for body metabolism process. Liver disease is one of serious health problems in developing countries including Indonesia. Liver damage is caused by viral infection, toxic agent exposure (medications, alcohol), hormonal disturbance, neoplasm and autoimmune diseases. The use of high dose paracetamol to reduce pain also leads to liver damage. Apple (Malus domestica) juice is a natural anti oxidant agent. This laboratory experimental study was performed to discover the effect of giving apple juice on damaged cell regeneration due to the use of paracetamol. The study was performed in 21 male mice from Swiss-Webster strain that were divided into group I, II, and III. Group, I served as control while group II received 1 mg/ml paracetamol dose for 5 days and Group III received 1 mg/ml paracetamol for 5 days and 1 ml of apple juice on the 5th to 10th day. The observation of the mice liver cells was conducted using a light microscope with 400x magnification to get the number of necrotic liver cells per view field. The results of this study showed a difference in the number of necrotic liver cells between Group II and III. ANOVA statistical test ( = 0.05) concluded that apple juice significantly helps regeneration process in damaged liver cells caused by paracetamol.

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