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The Relationship Between Depression Symptoms Measured by The Patient Health Questionnaire-9 and Blood Sugar Levels in Type 2 Diabetes Mellitus Outpatient Patients at Raden Achmad Basoeni General Hospital, Mojokerto, East Java, 2025 Shehnaz Neisa Rasyid; I Ketut Tirka Nandaka; Diah Purwaningsari
Journal of Social Research Vol. 5 No. 3 (2026): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i3.3072

Abstract

The purpose of this research was to determine the correlation of depressive symptoms in patients with T2DM on 2-hour postprandial (PP) blood sugar levels. This research was an analytical observational (quantitative) study with a cross-sectional design and a simple random sampling technique. This study was conducted at R.A Basoeni Regional General Hospital, Mojokerto, East Java. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9), while 2-hour PP blood sugar levels were measured using a glucometer conducted in July-August 2025 with 101 respondents. The data obtained were analyzed using the Chi-Square test to determine the correlation between the two variables. The results of this study indicate a significant correlation with p = 0.010 and ? = 0.05, which mean p < ?. Therefore, it can be concluded that there is a statistically significant relationship between depressive symptoms and 2-hour postprandial blood sugar levels in patients with T2DM. This finding confirms that depressive symptoms play a significant role in influencing blood sugar stability in patients with T2DM.
Effectiveness of Ethanol Extract From Sea Pandan (Pandanus Tectorius) on Hydroxyproline Levels as A Parameter For Collagen Formation in The Healing Process of Incision Wounds in Male Rattus Norvegicus Vanessa Hedyana Putri; Roostantia Indrawati; Andi Abdullah; Afifah Sekarkusuma; Shehnaz Neisa Rasyid
Asian Journal of Social and Humanities Vol. 4 No. 4 (2026): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v4i4.674

Abstract

This study aims to determine the effectiveness of ethanol extract gel of sea pandan fruit on hydroxycroline levels as a parameter for collagen formation in the healing process of incisional wounds of male white rats (Rattus norvegicus). This study is a laboratory experimental research with a post-test only control group design. The experimental animals used were male white rats which were divided into negative control groups (Gel Base), positive control (Bioplacenton®), and treatment groups with marine pandan ethanol extract gel concentrations of 10%, 20%, and 30%. The treatment was carried out for 10 days at the Integrated Biomolecular and Hyperbaric Laboratory, Faculty of Medicine, Hang Tuah University, Surabaya. The measured parameter was the level of hydroxychlorine of skin tissue. The results showed that there was a significant difference in hydroxyproline levels between treatment groups (p=0.032). The 20% concentration provides the most optimal effect with the highest average hydroxycroline levels and the narrowest data distribution, signaling more consistent fibroblast stimulation and collagen deposition. A concentration of 10% indicates high variability so the effect is less stable, while a concentration of 30% provides a moderate effect that may be affected by mild irritation. The conclusion of this study is that sea pandan fruit ethanol extract gel has the potential to accelerate the healing of incision wounds through increasing hydroxycrolin levels as an indicator of collagen formation.