Ach Zakyah Al Fauzi
Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Overview Of Toddlers Diarrhea Self-Medication At Pharmacy “X”, Sidoarjo, January-March 2025 Ach Zakyah Al Fauzi; Andri Priyoherianto; Lailatus Sholihah
Jurnal Riset Kefarmasian Indonesia Vol. 8 No. 2 (2026): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v8i2.899

Abstract

Diarrhea is one of the common health problems in toddlers and is often treated through self-medication by the community. Choosing the right medicine is very important to avoid complications, considering the low immune system of toddlers and the potential risks of using drugs without a doctor's prescription. This study used a qualitative descriptive design, the study was conducted at the "X" Pharmacy, Sidoarjo District, Sidoarjo Regency from January to March 2025. The sample consisted of 90 parents/caregivers of toddlers who bought diarrhea medicine for their children and met the inclusion criteria. The results showed that the types of drugs most often chosen for self-medication for diarrhea in toddlers were probiotics (46%), zinc supplements (41%), oralit (11%), and a combination of kaolin-pectin (2%). The characteristics of the respondents were mostly aged 20-25 years and had a high school or diploma education level. The choice of diarrhea medicine in self-medication in toddlers was dominated by the use of probiotics and zinc, in accordance with the recommendations of the Indonesian Ministry of Health in handling diarrhea. However, there is still a need to improve education to the public regarding the rational use of drugs and clinical indications for giving antibiotics. An active role is needed for health workers, especially pharmacists, in providing accurate information to the public to prevent the negative impacts of inappropriate self-medication.
Comparison of Ethyl Acetate and Ethanol Solvents on Total Flavonoid Content from (Gnetum gnemon L.) Using UV-Vis Spectrophotometry Panji Ratih Suci; Valiandri Puspadina; Andri Priyoherianto Andri Priyoherianto; Nurfitriawatie Nurfitriawatie; Fahmi Ardianti Purnawiranita; Achmad Misbakhul Maulana; Ach Zakyah Al Fauzi
Jurnal Riset Kefarmasian Indonesia Vol. 8 No. 2 (2026): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v8i2.951

Abstract

Melinjo peel (Gnetum gnemon L.) is an agricultural by-product that is generally underutilized, despite its high content of flavonoid compounds with potential antioxidant activity. This study aimed to compare the effectiveness of ethanol and ethyl acetate as extraction solvents for flavonoids from melinjo peel based on differences in solvent polarity. Extraction was carried out using the maceration method, followed by quantitative analysis using spectrophotometry. Sample preparation involved drying and pulverizing the melinjo peel, extraction with ethanol and ethyl acetate at a material-to-solvent ratio of 1:10, phytochemical screening, thin-layer chromatography analysis, preparation of a quercetin calibration curve, and determination of total flavonoid content. Total flavonoid content was determined through the formation of a complex with aluminum chloride, and absorbance was measured at a wavelength of approximately 430 nm. Statistical analysis was conducted to evaluate differences between the two solvents. The results demonstrated that the ethanol extract produced a higher total flavonoid content (51.86 mg quercetin equivalent per gram of extract) compared to the ethyl acetate extract (46.05 mg quercetin equivalent per gram). The higher extraction efficiency of ethanol is attributed to its greater polarity, which enhances the solubilization of polar flavonoid compounds. In conclusion, ethanol is a more effective solvent than ethyl acetate for extracting flavonoids from melinjo peel, and these findings support the potential utilization of melinjo peel as a natural source of bioactive compounds for applications in the food, pharmaceutical, and cosmetic industries.