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ANALISIS KADAR BETA KAROTEN DAN VITAMIN C BUAH JUWET (Syzigium cumini ) secara SPEKTROFOTOMETRI UV-VIS Panji Ratih Suci; Nadya Hapsari; Reny Dwi
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.601

Abstract

Beta-carotene (?-Carotene) is an organic compound and is classified as a terpenoid. ?-Carotene is a red-orange pigment that is very abundant in plants and fruits. Beta-carotene is thought to have many functions that other compounds do not have (Subawati, 2009). The aim of this study was to determine ?-carotene levels in juwet fruit (Syzygium Cumini) by UV-Vis spectrophotometry. Juwet fruit samples (Syzygium Cumini) were extracted with acetone as a solvent. The extract obtained was extracted again with petroleum ether solvent, then saponified with 15% KOH solvent in methanol. The extract was liberated with distilled water. The extract obtained was dried over anhydrous Na2SO4. The extract obtained was analyzed qualitatively using Thin Layer Chromatography, and UV-Vis spectrophotometry at a wavelength of 332.1539 nm. The average level of ?-carotene in juwet fruit was 1.25 mg. Analysis of Vitamin C levels was carried out at a wavelength of 265.3 nm, the average level of Vitamin C in juwet fruit was 1.473
Formulasi dan Uji Mutu Fisik Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) sebagai Sabun Cair: Formulation and Physical Quality of Binahong Leaves Extract (Anredera cordifolia (Ten.) Steenis) as Liquid Soap Chyntia Maharani; Panji Ratih Suci; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.908 KB) | DOI: 10.25026/mpc.v13i1.443

Abstract

Acne or Acne vulgaris is a problem that is often experienced at all ages, especially in adolescents. One of the causes of acne is that the polysebase ducts (oil glands in the skin and hair) become blocked and cause the production of skin oil (sebum) which becomes food for bacteria. The flavonoids contained in the leaves of Binahong (Anredera cordifolia (Ten.) Steenis) can inhibit bacterial growth. This study aims to formulate the Binahong leaf extract (Anredera cordifolia (Ten.) Steenis) into liquid soap preparation and evaluate the physical quality of the preparation. The extraction method used in this study was maceration using 96% ethanol as a solvent. Liquid soap Binahong Leaf extract (Anredera cordifolia (Ten.) Steenis) is made into four formulas, namely F0 (containing 0% binahong leaf extract), F1 (containing 2% binahong leaf extract), F2 (containing 4% binahong leaf extract), and F3 (contains 6% binahong leaf extract). The physical quality test for liquid soap preparations includes organoleptic tests, homogeneity, pH, high foam, and dispersibility. The test results of the four liquid soap formulations showed that the four formulas did not experience organoleptic changes, were homogeneous, and met the pH requirements of 9.5-11. The pH range of liquid soap that meets the SNI requirements (06-3734-2006) is 8-11, the foam height range is 25-60 mm, and the spreadability range is 3-5 cm.
Formulasi dan Uji Mutu Fisik Sediaan Sabun Cair Herbal Ekstrak Daun Kemangi (Ocimum sanctum L.): Formulation and Physical Quality Test of Basil Leaf Extract Herbal Liquid Soap (Ocimum sanctum L.) Sukma Dewi Ayu Anggraini; Panji Ratih Suci; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.781 KB) | DOI: 10.25026/mpc.v13i1.465

Abstract

Acne is a skin problem that is often a problem for most teenagers in Indonesia. This acne can occur due to a lack of facial hygiene, which causes the growth of bacteria. Basil (Ocimum sanctum L.) is a plant that grows in Indonesia and contains alkaloids, saponins, flavonoids and tannins which can inhibit the growth of bacteria. The purpose of this study was to utilize Basil extract (Ocimum sanctum L.) into liquid soap preparation and evaluate the physical quality of the preparation. Basil extract (Ocimum sanctum L.) can be obtained by using the maceration method using 96% ethanol as a solvent. Liquid soap preparation formulations are made with extract concentrations of 2%, 4%, and 6% with a uniform liquid soap base. Evaluation of liquid soap preparations includes tests for homogeneity, organoleptic, pH, dispersibility, and high foam. The results of the three liquid soap formulations showed that the three formulations were homogeneous and there was no organoleptic change, the pH range of liquid soap 9-11 which fulfilled the pH requirements of liquid soap according to SNI No. 06-4085-1996, namely 8 - 11, the spreadability test range is 2.7 - 3cm and the foam height test range is 3 ? 8,5cm.
AKTIVITAS ANTIOKSIDAN DAN SKRINNING FITOKIMIA EKSTRAK ETANOL DAUN SINTRONG (Crassocephalum crepidioides (Benth) S. Moore) indah trilestari; Panji Ratih Suci; Erna Fitriany
AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Antioxidants is an important role in the body's defense against disease, because antioxidant compounds are able to prevent the bad influence caused by free radicals. Sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore) has a compound of saponins, tannins, alkaloids and flavonoids known to be used as antioxidants. The purpose of the study to determine the activity of antioxidant and IC50 values as well as compounds contained there in and compared with Vitamin C as a positive control of antioxidant activity of sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore). The research method uses DPPH attenuation method and then calculated by spectrophotometry to determine the antioxidant content. The results showed that ethanol extract of sintrong leaves has antioxidant activity that can ward off free radicals with IC50 value of 52.49 mg / ml. Conclusion there is antioxidant activity in sintrong leaf extract (Crassocephalum crepidioides (Benth) S. Moore) with IC50 value of 52.49 mg / ml (strong) but the antioxidant activity obtained greater positive control than the extract. This data is supported by the Independent T-Test the value of the thitung > ttabel, which means that there are differences in the antiokxidant activity of sintrong leaves and vitamin C. Keywords: Sintrong leaf, Free Radicals, Antioxidants, IC50.
Eco-friendly silver nanoparticles (AgNPs) fabricated by green synthesis using Capsicum annum L. extract: biosynthesis, characterization, and antibacterial activity Erna Fitriany Fitriany; Andri Priyoherianto; Panji Ratih Suci
ALOTROP Vol. 7 No. 1 (2023): Alotrop 2023
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v7i1.26546

Abstract

Silver nanoparticles (AgNPs) have many benefits in the health sector, it has antimicrobial and biomedical Activity. AgNPs can be synthesized by using green chemistry or using chemical substances, such as NaBH4. Green synthesis of AgNPs is an environmentally friendly alternative and has cost-effective production. Capsicum annuum L. combined with Saffron extract was used to synthesize AgNPs. The biosynthesis, characterization, and antibacterial activity of AgNPs were studied in this research. The synthesized AgNPs were characterized by UV- Visible spectroscopy (UV-Vis), Fourier- transform Infrared Spectroscopy (FTIR), and Particle Size Analyzer (PSA). The formation of AgNPs was confirmed by optical performance using UV-VIS spectroscopy and showing a peak of AgNPs at 407 nm. Capsicum Annuum L. combined with Saffron extract contained C-H, C-N, and C=O groups. The particle size was characterized using PSA, the size is 37,74 nm. Capsicum Annuum L. combined with Saffron extract has good antibacterial activity.  Keywords: Green Synthesis, AgNPs, Capsicum annuum L, Saffron.
Uji Aktivitas Antidiabetes Ekstrak Kulit Melinjo (Gnetum Gnemon L.) pada Mencit (Mus musculus) Ida Kristianingsih; Panji Ratih Suci; Zuanta Pangestuti
Jurnal Farmasi Indonesia AFAMEDIS Vol. 4 No. 2 (2023): AFAMEDIS || JURNAL FARMASI INDONESIA
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Diabetes is one of a number of diseases that result in too much sugar levels in the blood (high blood glucose), treatment with the example of the drug Glibenclamide can reduce blood sugar levels gradually, so alternative treatment is needed from natural ingredients. One of the natural ingredients that contain chemical compounds Flavonoids, Coumarins, and Triterpenoids, which have activity lowering blood sugar levels. The purpose of this study was to determine the activity of melinjo peel extract against antidiabetes in mice to determine the most effective dose of lowering blood sugar levels in male mice, in this study using this research method using melinjo peel extract (Gnetum gnemon L) with a dose of 200mg/kgBB ,250mg/kgBW and a dose of 42mg/kgBW which aims to determine the effect of melinjo peel extract as a decrease in blood sugar levels in male mice, shows that melinjo peel extract (Gnetum gnemon L.) is the most effective in reducing sugar levels at a dose of 42mg/kgBW, compared with positive control and doses of 28mg/kgBW and 35mg/kgBW. The results of the study concluded that melinjo peel extract (Gnetum gnemon L) in the 28mg/kgBW, 35mg/kgBW and 42mg/kgBW dose groups were the most effective in reducing blood sugar levels. 42 mg/kg body weight. The conclusion is that there is antidiabetic activity in the extra skin of melinjo (Gnetum gnemon L.) both at doses of 28mg/kgBW, 35mg/kgBW and 42mg/kgBW but the most effective for reducing blood sugar levels is at a dose of 42mg/kgBW compared to the positive control. This data is supported by repeated ANOVA test with a significant value of p=0.012 (p>0.05), which means that all groups have significant differences in both the extract and the comparison group used.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MARKISA KUNING (Passiflora edulis var. flavicarpa degener) PADA BAKTERI Escherchia coli Panji Ratih Suci; Latiful Fauziyah; Pramudita Putra Dwi Ramadhan
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.658

Abstract

Diarrhea is a condition in which the body loses most of its fluids and electrolytes caused by defecating three or more times a day with a thick, fluid consistency. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of passion fruit (Passiflora edulis var. flavicarpa Degener) to inhibit the growth of Escherichia coli bacteria. The extraction method used maceration with 70% ethanol solvent and then continued with the antibacterial activity test at a concentration of 10%, 20%, and 30% using the disk diffusion method with 3x replication. The results of the antibacterial activity test were analyzed by the method of one-way ANOVA followed by a post hoc test (Tukey). The results of data analysis showed that the ethanolic extract of yellow passion fruit leaves had activity to inhibit the growth of Escherichia coli bacteria with the average diameter of the inhibition zone at a concentration of 10% (3.85 mm), at a concentration of 20% (6.61 mm), at a concentration of 30% (11.69 mm), and in the data analysis test, a value (sig 0.05) was obtained, which means that there are differences in the antibacterial activity of each concentration and positive control.
PEMBUATAN GRANUL JAMU KUNYIT ASAM SEBAGAI ANTIOKSIDAN ALAMI DI DESA KALITENGAH TANGGULANGIN SIDOARJO Panji Ratih Suci; Erna Fitriany; Zuanta Pangestutik; Andri Priyoherianto; Fahmi Ardianti Purnawiranita
Jurnal Pengabdian IKIFA Vol. 4 No. 1 (2025): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Turmeric is a type of rhizome that contains secondary metabolites that have antioxidant activity. Generally, turmeric is processed into spices or as raw material for herbal medicine such as tamarind turmeric herbal medicine. This activity aims to introduce the community in Kalitengah Tanggulangin Village, Sidoarjo, to processing tamarind turmeric granules as a natural antioxidant, involving PKK women from Kalitengah village. Activities The method used during the service process uses a participatory approach consisting of observation, training and evaluation. Questionnaires were given to 49 PKK women respondents. The pretest was carried out before the training was carried out, and continued with a post-test after the respondents received the training and tried instant turmeric powder for themselves. Evaluation results based on respondents' answers to the questionnaire given showed an increase in knowledge related to tamarind turmeric by 100%, knowledge of the benefits of turmeric by 81.6%, knowledge about granules by 81.6% and readiness to take part in training increased by 98%. These results show that this training had a positive impact on PKK mothers in Kalitengah village, Sidoarjo
Bahasa Indonesia WORKSHOP PEMBUATAN LILIN AROMATERAPI MINYAK ATSIRI SEREH DAN LAVENDER DI DESA KLANTINGSARI DUSUN WONOSARI RT 07/RW 02 TARIK SIDOARJO Panji Ratih Suci; Erna Fitriany; Elly Purwati; Zuanta Pangestutik; Muflikhatul Umaroh; Fahmi Ardianti Purnawiranita
Jurnal Pengabdian IKIFA Vol. 4 No. 2 (2025): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Aromaterapi adalah suatu bentuk perawatan yang memanfaatkan bahan-bahan aromatik dengan aroma khas yang memiliki kemampuan untuk memberikan efek relaksasi. Dengan keharuman yang menenangkan, aromaterapi membantu mengurangi rasa tegang akibat berbagai tekanan. Banyak produk aromaterapi yang tersedia dalam bentuk sediaan farmasi, dirancang khusus untuk membantu mengatasi gejala atau kondisi insomnia. Kegiatan Pengabdian kepada Masyarakat (PkM) bertujuan untuk mengenalkan proses pembuatan lilin aromaterapi minyak atsiri sereh dan lavender. Kegiatan PkM dilaksanakan di Desa Klantingsari, Dusun Wonosari RT07/RW 02, Tarik Sidoarjo pada hari Sabtu, 29 Juni 2024. Metode yang digunakan pada saat proses pengabdian menggunakan pendekatan partisipatif yang terdiri dari pengamatan, pelatihan, dan evaluasi. Kuesioner diberikan kepada 55 responden, pre-test dilakukan sebelum pelaksanaan pelatihan, dan dilanjutkan dengan post-test setelah para responden menerima pelatihan dan mencoba pembuatan lilin aromaterapi. Hasil evaluasi berdasarkan jawaban responden pemahaman aromaterapi dan manfaatnya sebesar 94,55%, pemahaman metode sebesar 90,91%, pemahaman alat dan bahan yang digunakan 100%. Hasil ini menunjukan peserta pelatihan menunjukkan antusiasme yang tinggi dalam mengikuti kegiatan dan partisipasi aktif mereka sepanjang kegiatan, sehingga menjadi sumber nilai ekonomi tambahan bagi peserta. Masyarakat berharap agar pembinaan dapat terus berlanjut di masa mendatang.
Workshop Pengenalan Dini Tenaga Teknis Kefarmasian Dan Apoteker Di Tk Asy Syarif Mojokerto Panji Ratih Suci; Erna Fitriany; Muflikhatul Umaroh; Andri Priyoherianto; Achmad Zakyah Al Fauzi
Jurnal Pengabdian IKIFA Vol. 4 No. 3 (2025): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Workshop pengenalan dini tenaga teknis kefarmasian dan apoteker di TK Asy Syarif Mojokerto dilaksanakan dengan tujuan memberikan pemahaman awal mengenai profesi kefarmasian kepada anak usia dini secara edukatif dan interaktif. Kegiatan ini melibatkan 21 peserta didik usia 4–6 tahun dan guru pendamping, menggunakan metode pembelajaran bermain sambil belajar, media alat peraga, serta simulasi peran. Hasil kegiatan menunjukkan tingkat partisipasi yang tinggi serta kemampuan anak dalam mengenali peran apoteker dan pentingnya penggunaan obat yang tepat. Workshop ini tidak hanya memperluas wawasan anak mengenai dunia kefarmasian, tetapi juga menanamkan nilai-nilai positif tentang kesehatan dan menumbuhkan ketertarikan terhadap profesi di bidang kesehatan sejak usia dini. Berdasarkan hasil observasi, sebanyak 90% siswa (19 dari 21) menunjukkan antusiasme tinggi dengan partisipasi aktif dalam sesi tanya jawab dan simulasi peran. Selain itu, 85% siswa (18 dari 21) berhasil mengidentifikasi fungsi apoteker sebagai tenaga yang memberikan obat dan membantu menjaga kesehatan masyarakat. Dari tes pemahaman, 80% siswa (17 dari 21) mampu menjawab dengan benar pertanyaan terkait cara mencuci tangan yang benar dan pentingnya obat dalam menjaga kesehatan. Dengan demikian, kegiatan ini berkontribusi dalam pengembangan pendidikan karakter dan pembentukan aspirasi karier anak pada tahap awal perkembangan.