Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) Journal Medical Informatics Technology
Maximus M. Taek
Widya Mandira Catholic University
Computer Science & IT Dentistry Engineering Health Professions Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Consumer preferences and marketing strategy for black pule (Alstonia spectabilis) antimalarial tablet prototypes in South Central Timor Novia Maulina; Sari Dewi Setyowati; Salma Rizqika Irwanadi; Hajar Sugihantoro; Riza Ambar Sari; Ziyana Walidah; Maximus M. Taek; Burhan Ma’arif
International Journal of Public Health Science (IJPHS) Vol 15, No 2: June 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i2.26853

Abstract

Malaria remains endemic in eastern Indonesia, and resistance to conventional antimalarial drugs necessitates alternative treatments. Black pule (Alstonia spectabilis) is one of the plants that has been researched and claimed to be a natural ingredient that can treat malaria. Black pule prototype has been prepared for the downstream stage through commercialization. Before that, it is necessary to conduct marketing research to ensure the success of the marketing. Therefore, this study evaluates consumer preferences and formulates marketing strategies for black pule antimalarial tablets. This study involved 100 respondents selected using cluster and purposive sampling across three malaria-endemic sub-districts in South Central Timor Regency. Using a quantitative-descriptive approach, data were collected through questionnaires and analyzed with descriptive statistics. The results show that most consumer targets stated that the antimalarial tablet prototype of black pule has a good impression and characteristics. Approximately 69-77% of respondents rated the product positively across shape, color, taste, aroma, size, and overall organoleptic attributes. The results indicate that the majority of respondents gave positive evaluations and expressed a preference for the product’s shape, color, taste, aroma, size, and overall organoleptic characteristics. Findings support aggressive marketing strategies for herbal antimalarial tablets in endemic regions. Based on these findings, an aggressive S-O marketing strategy is recommended, emphasizing product promotion, participation in health-related expos, strengthened digital outreach, and concise educational initiatives to improve public acceptance of the herbal antimalarial tablet.
Computational Pharmacology Approach to Identify Antidiarrheal Candidates from Eleusine indica L.: Molecular Docking Simulation and Drug-likeness Prediction Targeting 5ZHP Receptor Faisal Akhmal Muslikh; Rizki Rahmadi Pratama; Syahputra Wibowo; Yanu Andhiarto; Burhan Ma’arif; Maximus M. Taek
Journal Medical Informatics Technology Volume 4 No. 2, June 2026
Publisher : SAFE-Network

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37034/medinftech.v4i2.142

Abstract

Diarrhea remains a significant global health concern with high morbidity and mortality rates, particularly in developing countries. The use of synthetic antidiarrheal drugs is associated with various adverse effects, necessitating the exploration of safer therapeutic alternatives derived from natural sources. This study aimed to evaluate the potential of secondary metabolite compounds from Eleusine indica as antidiarrheal candidates through an in silico approach, employing drug-likeness analysis and molecular docking simulation against the muscarinic acetylcholine M3 receptor (PDB ID: 5ZHP). Drug-likeness analysis was performed using the SwissADME web tool based on Lipinski's Rule of Five. Molecular docking simulation was conducted using Molegro Virtual Docker, with the root mean square deviation (RMSD) value employed as a validation parameter. The results revealed that the majority of the compounds satisfied Lipinski's criteria, indicating their potential as oral drug candidates. Docking method validation yielded an RMSD value of 0.777437 Å, confirming the validity and reliability of the docking procedure. Docking results suggested that compound M15 (andrographolide) and compound M13 [4-(1-hydroxyethyl)-2,6-bis(3-methylbut-2-en-1-yl)phenol] exhibited the lowest Rerank Scores of −116.686 and −114.300, respectively, which were notably lower than that of the positive control loperamide (−41.9287), suggesting potentially stronger binding affinity and more favorable interaction with the target receptor. However, these findings are predictive in nature and require further validation through experimental biological studies and molecular dynamics simulations to confirm actual binding stability and pharmacological effectiveness.
Co-Authors Burhan Ma’arif Burhan Ma’arif Faisal Akhmal Muslikh Hajar Sugihantoro Novia Maulina Riza Ambar Sari Rizki Rahmadi Pratama Salma Rizqika Irwanadi Sari Dewi Setyowati Syahputra Wibowo Yanu Andhiarto Ziyana Walidah