Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal AL-ULUM: JURNAL SAINS DAN TEKNOLOGI
Rizki Rahmadi Pratama
Universitas Islam Kalimantan MAB, Indonesia.
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Energy

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
ANTIDEPRESSANT ACTIVITY TEST OF RED BETEL LEAF ETHANOL EXTRACT (Piper crocatum) ON MALE WHITE MICE (Mus musculus) USING THE FORCED SWIM TEST METHOD Triswanto Sentat; Anita Apriliana; Siti Lili Rizki Sari; Novi Milasari; Ghina Adhila; Rizki Rahmadi Pratama; M. Hasan Andryanto
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 11, No 2 (2025)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v11i2.18542

Abstract

Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, polyphenols, tannins, and which is known for its antidepressant properties. The purpose of this study was to determine the effect of antidepressant activity of ethanol extract of red betel leaves on male white mice (Mus musculus) orally. The method used in testing antidepressants is the Forced Swim Test. Fifteen mice were divided into five groups: a positive control group receiving 3.5 mg/kg BW amitriptyline, a negative control group, and three groups receiving 200, 400, and 800 mg/kg BW of the extract. The antidepressant effect was measured by observing the immobility of mice during swimming. The results of the study using paired sample t-Test analysis showed that there was a difference in immobility before and after, in the 400 mg/kg BW extract and 3.5 mg/kg BW amitriptyline dose groups had significant differences.
Co-Authors Anita Apriliana Ghina Adhila M. Hasan Andryanto Novi Milasari Siti Lili Rizki Sari Triswanto Sentat