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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmiah Farmako Bahari Jurnal Pengabdian Masyarakat Asia Journal of Pharmacy Science and Technology JPMP Journal Medical Informatics Technology
Yanu Andhiarto
Hang Tuah University
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Perbandingan Kualitas Suplemen Minyak Ikan Layang (Decapterus ruselli) Menggunakan Bentonit Dengan Berbagai Konsentrasi Pada Tahap Bleaching Yanu Andhiarto; Santi Wijaya
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 15 No. 02 Desember 2018
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (794.735 KB) | DOI: 10.30595/pharmacy.v15i2.3570

Abstract

Suplemen minyak ikan termasuk dalam salah satu produk pengembangan hasil perikanan laut yang cukup potensial untuk dikembangkan terutama dalam bidang kefarmasian karena mengandung asam lemak tidak jenuh yang merupakan komponen esensial bagi tubuh manusia, terutama asam lemak rantai panjang asam eikosapentaenoat (EPA) dan asam dokosaheksaenoat (DHA). Minyak ikan hasil ekstraksi mengandung pengotor sehingga perlu dilakukan pemurnian untuk mendapatkan minyak ikan dengan mutu baik. Bentonit merupakan adsorben yang dapat meningkatkan mutu dan memperbaiki warna minyak ikan. Penelitian ini bertujuan untuk menentukan karakteristik mutu dan perbandingan karakteristik mutu hasil pemurnian minyak ikan layang (Decapterus russelli) menggunakan bentonit konsentrasi 1, 3, dan 5% pada tahap bleaching. Penelitian ini dilakukan 3 tahapan yaitu degumming, refining, dan bleaching, kemudian dilakukan uji karakteristik mutu minyak ikan. Dari hasil penelitian, pemurnian minyak ikan layang terbaik pada konsentrasi bentonit 3% menghasilkan minyak ikan yang memenuhi persyaratan International Fish Oil Standard (IFOS) dengan nilai kadar asam lemak bebas sebesar 0,4406±0,0265% (b/b); bilangan peroksida sebesar 3,9953±0,0742 mEq/kg; bilangan p-anisidin sebesar 13,6624±1,9574 mEq/kg; bilangan total oksidasi sebesar 21,6531±1,8150 mEq/kg; dan kejernihan berturut-turut 74,6996±1,9363; 94,4950±1,5724; 95,1060±1,667; 95,6906±1,4371; dan 95,9356±1,3427 %T berturut-turut pada panjang gelombang (λ) 450, 550, 620, 665, dan 700 nm. Hasil penelitian menunjukkan bahwa pemberian bentonit berpotensi sebagai adsorben dalam proses pemurnian minyak ikan kasar ditandai dengan karakteristik mutu menjadi lebih baik. Hasil uji one-way ANOVA dan Kruskal-Wallis perbedaan konsentrasi bentonit menunjukkan perbedaan nyata terhadap nilai analisis bilangan asam lemak bebas dan kejernihan. Namun tidak berbeda nyata terhadap nilai analisis bilangan peroksida, p-anisidin, dan bilangan total oksidasi.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% DAUN MIMBA (Azadirachta indica A. Juss. ) DENGAN METODE EKSTRAKSI PERKOLASI TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Yanu Andhiarto; Rina Andayani; Nur Hidayatul Ilmiyah
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.99

Abstract

Skin infections most often found in developing countries, especially in the tropics, are purulent skin inflammation (pyoderma), the main cause of Staphylococcus aureus. The increasing number of cases of bacteria that are resistant to antibacterial can encourage the extraction of sources of antibacterial drugs from natural ingredients. One of the plants that is thought to have the antibacterial activity of Staphylococcus aureus is the Neem plant. In this study an antibacterial activity test was carried out with the well diffusion method from 96% ethanol extract of Mimba leaves extracted by percolation method. Phytochemical screening tests obtained 96% ethanol extract of Mimba leaves containing alcaloid, saponins, tannins, steroids / terpenoids and flavonoids. The results of the study on the antibacterial activity test showed a concentration of 75% ethanol extract of 96% Mimba leaves classified as having strong activity, at a concentration of 50% and 25% classified as having moderate activity. It concluded that the three concentrations of 96% ethanol extract of Mimba leaves were able to inhibit the growth of Staphylococcus aureus bacteria.
Pelatihan Pembuatan Jamu pada Siswa SMA di Kabupaten Banyuwangi sebagai Upaya Pelestarian Budaya dan Menanamkan Enterprenuership Suciati Suciati; Wiwied Ekasari; Neny Purwitasari; Rice Disi Oktarina; Lidya Tumewu; Yanu Andhiarto; Hanifa Rahma Putri; Tutiek Purwanti; Sudjarwo Sudjarwo
Jurnal Pengabdian Masyarakat Vol 4 No 1 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i1.1333

Abstract

Siswa SMA sebagai generasi penerus bangsa berperan penting dalam upaya kesehatan masyarakat. Jamu merupakan warisan budaya bangsa yang harus terus dikenalkan kepada generasi muda supaya dapat dijaga kelestariannya. Peran jamu dalam upaya pemeliharaan kesehatan masyarakat sudah tidak diragukan lagi. Tujuan dari kegiatan ini adalah untuk memberikan pelatihan pembuatan jamu kepada siswa SMA di Kabupaten Banyuwangi. Sebanyak 39 orang siswa SMA sebagai peserta mendapatkan materi tentang cara pembuatan jamu yang baik dan benar serta keamanan produk jamu yang beredar di masyarakat. Selain itu peserta juga melakukan praktek pembuatan jamu kunyit asam dan masker wajah. Kegiatan ini diharapkan untuk meningkatkan pengetahuan dan keterampilan siswa SMA dalam pembuatan jamu serta meningkatkan jiwa kewirausahaan siswa SMA yang secara tidak langsung dapat meningkatkan perekonomian keluarga. Hasil yang diperoleh menunjukkan antusiasme peserta dalam mengikuti kegiatan ini serta hasil pretest dan postest menunjukkan peningkatan pengetahuan yang signifikan.
PENYULUHAN PENGGUNAAN ANTIBIOTIK YANG TEPAT DALAM UPAYA PENCEGAHAN RESISTENSI DI KELURAHAN WONOREJO SURABAYA Rina Andayani; Ana Khusnul Faizah; Nani Wijayanti Dyah Nurrahman; Liza Yudistira Yusan; Astrid Kusuma Putri; Ersanda Nurma Praditapuspa; Hardiyono Hardiyono; Yanu Andhiarto
Jurnal Pengabdian Masyarakat Pesisir VOLUME 1 NO 2
Publisher : Universitas Hang Tuah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/jpmp.v1i2.75

Abstract

Antibiotik merupakan zat-zat kimia yang dapat menghambat dan membunuh bakteri yang digunakan masyarakat untuk menangani penyakit infeksi. Namun, penggunaan antibiotik yang tidak rasional dan tepat dapat menyebabkan resistensi bakteri terhadap antibiotik, dibuktikan dari data di Rumah Sakit Dr Kariadi yang menunjukkan bahwa semua isolat dari darah memiliki tingkat multiresisteni tinggi terhadap antibiotik yaitu 45-65%. Oleh karena itu dibutuhkan edukasi kepada masyarakat terkait bagaimana penggunaan antibiotik yang benar dan tepat kepada masyarakat. Penyuluhan diselenggarakan di kantor kelurahan Wonorejo dan dihadiri oleh 57 ibu-ibu PKK. Kegiatan ini bertujuan meningkatkan tingkat pengetahuan masyarakat Wonorejo terjadap penggunaan antibiotik yang benar. Evaluasi dilakukan dengan pengisian kuisioner sebelum dan sesudah penyuluhan dilakukan kepada masyarakat. Berdasarkan hasil kuisioner yang dianalisis diperoleh adanya peningkatan pengetahuan peserta dari kategori rendah (4,5) menjadi baik (6,8). Kegiatan penyuluhan dapat dilakukan secara rutin untuk meningkatkan kesadaran masyarakat dalam penggunaan antibiotik secara tepat.
Enhancing the Knowledge and Skill of PKK and Karang Taruna Cadres in The Innovation of Mangosteen Fruit Products Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Lidya Tumewu; Yanu Andhiarto; Fatin Fadhilah Hasib; Tri Widiandani; Kholis Amalia Nofianti
Jurnal Pengabdian Masyarakat Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i2.1897

Abstract

Purpose: The current community service activities aim to provide knowledge and skills related to mangosteen and its processed products to the Songgon Village community Method: Transfer of knowledge and skill by lecturing and practice. Pre and post-tests were carried out to evaluate the participants’ knowledge before and after the workshop. Practical Applications: The knowledge and skill gained by PKK and Karang Taruna cadres in this workshop can be implemented in daily life. The participants learned how to make innovative products from mangosteen fruit so that it can be produced commercially. Thus, in the long term is expected to increase the income of Songgon Village Community. Conclusion: The results showed the participants' enthusiasm to participate in this activity, and the pre and post-tests demonstrated increased knowledge and skills. The next step requires intensive support for the Songgon Village community so that their products can be distributed commercially and provide economic benefits.
Computational Pharmacology Approach to Identify Antidiarrheal Candidates from Eleusine indica L.: Molecular Docking Simulation and Drug-likeness Prediction Targeting 5ZHP Receptor Faisal Akhmal Muslikh; Rizki Rahmadi Pratama; Syahputra Wibowo; Yanu Andhiarto; Burhan Ma’arif; Maximus M. Taek
Journal Medical Informatics Technology Volume 4 No. 2, June 2026
Publisher : SAFE-Network

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37034/medinftech.v4i2.142

Abstract

Diarrhea remains a significant global health concern with high morbidity and mortality rates, particularly in developing countries. The use of synthetic antidiarrheal drugs is associated with various adverse effects, necessitating the exploration of safer therapeutic alternatives derived from natural sources. This study aimed to evaluate the potential of secondary metabolite compounds from Eleusine indica as antidiarrheal candidates through an in silico approach, employing drug-likeness analysis and molecular docking simulation against the muscarinic acetylcholine M3 receptor (PDB ID: 5ZHP). Drug-likeness analysis was performed using the SwissADME web tool based on Lipinski's Rule of Five. Molecular docking simulation was conducted using Molegro Virtual Docker, with the root mean square deviation (RMSD) value employed as a validation parameter. The results revealed that the majority of the compounds satisfied Lipinski's criteria, indicating their potential as oral drug candidates. Docking method validation yielded an RMSD value of 0.777437 Å, confirming the validity and reliability of the docking procedure. Docking results suggested that compound M15 (andrographolide) and compound M13 [4-(1-hydroxyethyl)-2,6-bis(3-methylbut-2-en-1-yl)phenol] exhibited the lowest Rerank Scores of −116.686 and −114.300, respectively, which were notably lower than that of the positive control loperamide (−41.9287), suggesting potentially stronger binding affinity and more favorable interaction with the target receptor. However, these findings are predictive in nature and require further validation through experimental biological studies and molecular dynamics simulations to confirm actual binding stability and pharmacological effectiveness.
CHARACTERISTICS OF REFINED CARRAGEENAN FROM Eucheuma spinosum WITH POTASSIUM HYDROXIDE SOLVENT USING MICROWAVE ASSISTED EXTRACTION (MAE) METHOD IN VARIOUS EXTRACTION TIMES Yanu Andhiarto; Nurita Pusparini
Jurnal Ilmiah Farmako Bahari Vol 16 No 1 (2025): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v16i1.3221

Abstract

Extraction time with Microwave Assisted Extraction (MAE) influences the yield and quality of Carrageenan from Eucheuma spinosum. This research aims to determine the effect of extraction time using microwave-assisted extraction (MAE) on the yield value and quality parameters of E. spinosum carrageenan, including water content, ash content, sulfate content and viscosity. E. spiosum was extracted using 0.5% NaOH base with the microwave-assisted extraction (MAE) method at varying extraction times of 2 minutes, 5 minutes and 8 minutes. The filtrate was filtered and precipitated with ethanol, drying and grinding until a fine carrageenan powder was obtained. Extraction time affected the yield where an increase in the average yield was received along with the length of extraction time. The highest yield in the 8-minute extraction was 17.62% ±0.368. Extraction time also influences the water content and viscosity of the obtained carrageenan but does not affect the extracted carrageenan's ash or sulfate content.
Co-Authors Andang Miatmoko Andayani, Rina Astrid Kusuma Putri Burhan Ma’arif Faisal Akhmal Muslikh Fatin Fadhilah Hasib Hanifa Rahma Putri Hardiyono Hardiyono Kholis Amalia Nofianti Lidya Tumewu Liza Yudistira Yusan Maximus M. Taek Nani Wijayanti Dyah Nurrahman Nur Hidayatul Ilmiyah Nurita Pusparini Praditapuspa, Ersanda Nurma Purwitasari, Neny Rice Disi Oktarina Rizki Rahmadi Pratama Santi Wijaya Suciati Suciati Sudjarwo Syahputra Wibowo Tri Widiandani Tutiek Purwanti Wiwied Ekasari