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Rasio Neutrofil-Limfosit (NLR) sebagai Penanda Disfungsi Hati pada Pendonor Darah Sukarela di Unit Transfusi Darah Palang Merah Indonesia Qurrotu A'yuni Auliya; Ririh Jatmi Wikandari; Bambang Supriyanta; Duwi Pudjiastuti; Yunita Rusidah
Jaringan Laboratorium Medis Vol 8 No 1 (2026): May 2026
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v8i1.14587

Abstract

Background: HBsAg is a marker for hepatitis B virus, which causes liver dysfunction characterized by elevated serum glutamic pyruvic transaminase (SGPT) levels. The neutrophil-lymphocyte ratio (NLR) has a positive effect on SGPT. Objective: To describe NLR as a marker of liver dysfunction in voluntary blood donors at the PMI Blood Donation Unit (UDD). Methods: Descriptive study to determine the role of NLR as a marker of liver dysfunction in voluntary blood donors. The study population consisted of voluntary blood donors at the PMI Blood Donation Unit in Salatiga, Central Java. Primary data collected through complete blood tests and SGPT measurements. Secondary data were HBsAg results in voluntary donors. Results: All 20 respondents (100%) had an average SGPT level of 20 U/L and non-reactive HBsAg results, with an average NLR value of 1.76. The highest age group was 26-35 years old, with 8 respondents (40%). Based on gender, 15 respondents (75%) were male and 5 respondents (25%) were female. The percentage of blood types A and O was 8 respondents (40%), while blood types B and AB were represented by 2 respondents (10%). Conclusions: NLR cannot be used as a marker of liver dysfunction based on SGPT and HBsAG parameters.
FAKTOR FAKTOR YANG MEMPENGARUHI KEPATUHAN PEMBATASAN CAIRAN PADA PASIEN HEMODIALISIS BARU DAN LAMA DI RSUD DR. MOEWARDI SURAKARTA Nurul Jatiningsih; Ratna Wirawati Rosyida; Duwi Pudjiastuti
Jurnal Medicare Vol. 5 No. 2 (2026): APRIL 2026
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v5i2.503

Abstract

Background: Hemodialysis is a method of replacing kidney function that uses a device called a dialyzer or artificial kidney. Hemodialysis patients are categorized as new patients (<1 year) while those on hemodialysis are categorized as old patients (>1 year). Differences in fluid restriction compliance are often seen between new and old hemodialysis patients. The purpose of this study was to determine the factors influencing fluid restriction compliance in new and old hemodialysis patients at Dr. Moewardi Hospital, Surakarta. Methods This study used a quantitative research method with a descriptive correlation design and a cross-sectional approach. Sampling used total sampling with 127 respondents at Dr. Moewardi Hospital, Surakarta undergoing hemodialysis. Data analysis used a contingency coefficient. The results showed that analysis of new patients showed a relationship between education, attitudes, family support, and psychological reactions with fluid restriction compliance (p-value 0.000 <0.05). For old patients, there was a relationship between gender, education, knowledge, and attitudes with fluid restriction compliance (p-value 0.000 <0.05). The conclusion of this study is that factors that influence new patients (<1 year) include education, attitude, family support, psychological reactions, while old patients (>1 year) include gender, education, knowledge, attitude.