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All Journal Equilibrium Journal of Chemical Engineering
Br. Lumban Raja, Teodora Merry Meriba V.J.
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Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Engineering Materials Science & Nanotechnology

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Polymers as Versatile Excipients Drug Delivery in Pharmaceutical Formulations: Innovations, Challenges, and Future Prospects Matovanni, Maudy Pratiwi Novia; Sulaiman, Yusri Risyad; Pramitha, Joanne Rizma; Br. Lumban Raja, Teodora Merry Meriba V.J.; Fauzi, Gefira Anelia
Equilibrium Journal of Chemical Engineering Vol 9, No 2 (2025): Volume 9, No 2 December 2025
Publisher : Program studi Teknik Kimia UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/equilibrium.v9i2.103724

Abstract

ABSTRACT. Polymers have become essential excipients in pharmaceutical formulations, significantly enhancing drug delivery systems due to their versatility, biocompatibility, and specialized properties. This review discusses the role of natural  and synthetic polymers, which are favored for their biodegradability and ability to improve drug stability and controlled release. The paper highlights innovations in polymer-based drug delivery, including the development of stimuli-responsive polymers that release drugs in response to specific environmental triggers and the integration of natural and synthetic polymers to create hybrid systems. Despite the advantages, challenges such as variability in natural polymer sources, potential toxicity of synthetic polymers, and regulatory hurdles remain. Future prospects include advancements in green and sustainable polymers, personalized medicine, and the use of nanotechnology to enhance drug delivery efficacy. This comprehensive examination underscores the importance of interdisciplinary research in overcoming existing barriers and advancing polymer-based drug delivery systems to improve patient outcomes. Keywords:Polymer, Drug delivery, Natural polymer, Synthetic polymer, Stimuli-responsive
Co-Authors Fauzi, Gefira Anelia Matovanni, Maudy Pratiwi Novia Pramitha, Joanne Rizma Sulaiman, Yusri Risyad