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All Journal Benzena Pharmaceutical Scientific Journal Indonesian Journal of Herbal and Biomedical Research
Khoirul Rista Abidin
Program Studi D4 Teknologi Laboratorium Medis, Politeknik ‘Aisyiyah Pontianak
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Pengaruh Waktu Fermentasi terhadap Konsentrasi Etanol pada Kulit Pisang Raja (Musa acuminata) dan Pisang Kepok (Musa paradisiaca L) Rahmadian Hoirunnisa; Khoirul Rista Abidin; Fath Dwisari; Abdurraafi' Maududi Dermawan
Indonesian Journal of Herbal and Biomedical Research Vol. 1 No. 1 (2025)
Publisher : Bahiraliya Natura Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66982/ijhbr.v1i1.5

Abstract

Banana peel waste is frequently discarded without proper management, potentially causing long-term environmental problems. However, banana peels can be valorized as a renewable feedstock for ethanol production. This study employed a quantitative experimental design consisting of four main stages: sample preparation, sulfuric acid hydrolysis, yeast fermentation with fermentation time variations of 72, 120, and 168 h, and ethanol content analysis. The ethanol content obtained from Raja banana (Musa acuminata) peels at fermentation times of 72, 120, and 168 h was 15%, 16%, and 17%, respectively. Meanwhile, ethanol yields from Kepok banana (Musa paradisiaca L.) peels at the same fermentation durations were 17.66%, 20.33%, and 22.33%, respectively. The results indicated that the highest ethanol content for both Raja and Kepok banana peels was achieved at a fermentation time of 168 h. Friedman test analysis revealed significance values of 0.368 (> 0.05) for Raja banana peels and 0.097 (> 0.05) for Kepok banana peels, indicating no statistically significant differences in ethanol content among the three fermentation durations. Overall, an increasing trend in ethanol content was observed for both banana varieties with prolonged fermentation time; however, statistical analysis confirmed that the differences were not significant across the tested fermentation periods.
POTENSI ANTIBAKTERI EKSTRAK AIR LENGKUAS PUTIH (Alpinia galanga L. Willd) YANG DIPERSIAPKAN SECARA TRADISIONAL TERHADAP Escherichia coli DAN Staphylococcus aureus Abdurraafi' Maududi Dermawan; Fakih Maulana Hasbullah; Khoirul Rista Abidin; Fath Dwisari
BENZENA Pharmaceutical Scientific Journal Vol 5 No 01 (2026): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v5i01.7810

Abstract

The growing challenge of antimicrobial resistance, compounded by the adverse effects of prolonged antibiotic regimens and surging healthcare costs, has driven the search for naturally derived alternative therapeutics. Alpinia galanga (L.) Willd., locally recognized as white galangal, occupies a central role in Indonesian ethnomedicine and culinary practices, making it a highly relevant subject for pharmacological screening. This study sought to evaluate the inhibitory capacity of A. galanga rhizome aqueous extracts against the clinical pathogens Staphylococcus aureus and Escherichia coli. Disk diffusion assays performed at four concentration gradients (25%, 50%, 75%, and 100%) demonstrated a clear dose-dependent antibacterial profile. For S. aureus, the resulting inhibition zone diameters were 7.36, 8.31, 8.93, and 9.94 mm, respectively. Parallel testing against E. coli yielded corresponding inhibition zones of 7.35, 8.07, 8.73, and 9.80 mm across the same concentrations. This investigation highlights the practical relevance of aqueous-based extraction, which accurately reflects traditional preparation methods, thereby validating its ethnopharmacological application. The empirical evidence confirms the extract's efficacy against both Gram-positive and Gram-negative bacterial strains. Such robust inhibitory activity not only reinforces its potential as a natural therapeutic agent but also establishes a scientific basis for its sustained use within traditional medicine frameworks.
Co-Authors Abdurraafi' Maududi Dermawan Fakih Maulana Hasbullah Fath Dwisari Fath Dwisari Rahmadian Hoirunnisa