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Generalized Anxiety Disorder with Somatic Symptom Presentation and Social Avoidance: A Case Report Alfiona Syafira Putri Arinda; Era Catur Prasetya
Journal of Scientific Research, Education, and Technology (JSRET) Vol. 5 No. 3 (2026): Vol. 5 No. 3 2026
Publisher : Kirana Publisher (KNPub)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58526/jsret.v5i3.1170

Abstract

Generalized Anxiety Disorder (GAD) is a psychiatric disorder that frequently presents with somatic complaints, which can lead to delayed diagnosis. This case report aims to describe the clinical manifestations, diagnostic process, and therapeutic response in a patient with GAD dominated by somatic symptoms. Case: A 63-year-old female patient presented with initial complaints of acid reflux sensation and epigastric pain since 2022. Medical examinations showed results within normal limits. The complaints progressed to palpitations, excessive anxiety, particularly in social situations, avoidance behavior, and sleep disturbances. The patient experienced a decline in social functioning, which subsequently improved after receiving pharmacological therapy and psychotherapy. Somatic symptoms in GAD are associated with autonomic nervous system activation and the brain–gut axis interaction. The diagnosis was established based on DSM-5-TR criteria, considering biopsychosocial aspects. Management using a combination of Selective Serotonin Reuptake Inhibitors (SSRIs) and Cognitive Behavioral Therapy (CBT) proved effective in improving the patient's symptoms and functioning.
Hiv Stadium 4 dengan Komplikasi dan Infeksi Oportunistik: A Case Report Alfiona Syafira Putri Arinda; Abdur Rohman
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 3 (2026): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i3.11803

Abstract

Human Immunodeficiency Virus (HIV) remains a significant public health problem in Indonesia, with approximately 660,000 people reported as living with the infection. This case report aims to describe the clinical diagnosis of HIV stage 4, supporting laboratory examinations, and the opportunistic complications associated with advanced disease progression. The patient presented with severe clinical manifestations consistent with wasting syndrome, including prolonged diarrhea lasting more than one month accompanied by blood, generalized weakness, and a bedridden condition accounting for more than 50% of daily activity. Additional findings included oral candidiasis, generalized pruritus, a history of tuberculosis infection, and previous diagnosis of B20 (+), along with hypoalbuminemia indicating severe nutritional deficiency. Laboratory evaluation demonstrated a significant reduction in CD4+ T-cell counts, confirming advanced immunosuppression. Patients in stage 4 HIV are highly vulnerable to multiple opportunistic infections and metabolic complications, such as tuberculosis reactivation, candidiasis, hyponatremia, hypokalemia, and severe hypoalbuminemia. Management of stage 4 HIV requires a comprehensive therapeutic approach, including treatment of active opportunistic infections, prevention of recurrent infections, nutritional support, and strengthening of immune function through antiretroviral therapy. Early recognition and integrated management are essential to improve patient outcomes and reduce mortality in advanced HIV cases.