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All Journal Jurnal Biologi Tropis CERATA
Dhea Syafitri Dwiyanti
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

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Review: Analisis Kualitatif Dan Kuantitatif Kandungan Hidrokuinon Dalam Krim Pemutih Wajah Dengan Berbagai Metode Analisis Dea Riski Pebrianti; Dhea Syafitri Dwiyanti; Hudaynu Patya Putri; Gyna Dalila Virginia; ⁠I Gede Eka Surya Buana; Eskarani Tri Pratiwi
CERATA Jurnal Ilmu Farmasi Vol 17 No 1 (2026): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v17i1.1426

Abstract

Analysis of the hydroquinone content in facial whitening cream can be carried out using qualitative and quantitative methods. Hydroquinone, although effective in reducing melanin production, is potentially dangerous if used excessively, namely it can cause skin irritation and serious health problems. Qualitative analysis can be carried out using thin layer chromatography (TLC) and color reaction methods, while quantitative analysis can use UV-Vis Spectrophotometry and High Performance Liquid Chromatography (HPLC). The results of the analysis show that many facial whitening cream products contain hydroquinone that exceeds the permitted limit (<2%), although some products are still within the safe limit. These findings emphasize the importance of strict supervision of cosmetics circulating on the market, in order to protect consumers from health risks. The choice of analytical method depends on specific needs, namely TLC is suitable for fast identification and HPLC for more accurate results on complex compounds.
Review Article: Drug-Related Problems in Hypertensive Patients in Pharmaceutical Practice Eti Agustiani; Keysha Nabilla Putri Marasabessy; Dhea Syafitri Dwiyanti; Ulfatul Mutthoimah; Tuhfatul Ulya
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11407

Abstract

Hypertension is a chronic disease with a high global prevalence and often requires combination therapy, which increases the risk of Drug-Related Problems (DRPs). This review aims to identify the types of DRPs, the most frequently implicated medications, causative factors, and pharmaceutical interventions based on various studies conducted in hypertensive patients. The literature review results indicate that common DRPs include drug interactions, ineffective therapy, the need for additional therapy, adverse drug reactions (ADRs), and inappropriate medication selection. Amlodipine, candesartan, valsartan, beta-blockers, and diuretics are among the medications most frequently associated with DRPs. Polypharmacy, non-adherence, comorbidities, and inadequate monitoring are the main contributing factors. Pharmaceutical interventions such as medication review, therapy monitoring, patient counseling, and adherence to clinical guidelines have been shown to be effective in reducing DRPs. The role of pharmacists is crucial to ensure the safety and effectiveness of hypertension therapy.
Co-Authors Dea Riski Pebrianti Eskarani Tri Pratiwi Eti Agustiani Gyna Dalila Virginia Hudaynu Patya Putri Keysha Nabilla Putri Marasabessy Tuhfatul Ulya Ulfatul Mutthoimah ⁠I Gede Eka Surya Buana