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Evaluation of Preceptorship Implementation among Pharmacy Professional Program Students at Universitas Mataram across Practice Settings Raisya Hasina; Siti Rahmatul Aini; Mahacita Andanalusia; Tuhfatul Ulya; Baiq Risky Wahyu Lisnasari; Winiayu Devhi Prasasthi; Baiq Aulia Ali; Gusti Ayu Pratitha Devinta Putri; Fawwaz Aqila Putri; Jasmine Zaskia Kaori
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol. 14 No. 3: July 2026
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v14i3.21078

Abstract

Preceptorship is widely implemented in pharmacist professional education to facilitate experiential learning and competency development during the Pharmacist Professional Practice Program (PKPA). However, evaluations of its implementation across different practice settings remain limited. This study aimed to evaluate the implementation of the preceptorship method among students of the Pharmacist Professional Study Program (PSPPA), Faculty of Medicine and Health Sciences, Universitas Mataram, during PKPA in community pharmacies, hospitals, public health centers, and pharmaceutical wholesalers. This study employed a mixed-methods design using a sequential explanatory approach. Quantitative data were collected through a structured questionnaire administered to PSPPA students to assess perceptions of preceptorship implementation across six domains. Qualitative data were obtained through in-depth interviews with 11 preceptors and analyzed using thematic analysis to further explain the quantitative findings. The quantitative results showed that all assessment domains were categorized as “very good,” with scores ranging from 82.5% to 88.3%. The highest score was observed in the student skill development domain (88.3%), followed by preceptor involvement (86.6%) and knowledge assessment through evaluation and feedback (85.0%). Qualitative findings revealed that preceptorship was implemented through three main stages: orientation, implementation, and evaluation. Orientation facilitated students’ adaptation to practice environments, while the implementation stage involved direct supervision, reflective discussions, assignments, and progressive responsibility. Evaluation was conducted continuously through observation, feedback, portfolios, and collaborative monitoring between preceptors and academic supervisors. Challenges identified included limited preceptor availability, variations in student readiness, and the relatively short duration of PKPA placements. In conclusion, the preceptorship method was implemented effectively across PKPA settings and contributed positively to students’ competency development. Strengthening student preparation, institutional support, and collaboration between academic institutions and practice sites may further optimize preceptorship implementation.
Review Article: Drug-Related Problems in Hypertensive Patients in Pharmaceutical Practice Eti Agustiani; Keysha Nabilla Putri Marasabessy; Dhea Syafitri Dwiyanti; Ulfatul Mutthoimah; Tuhfatul Ulya
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11407

Abstract

Hypertension is a chronic disease with a high global prevalence and often requires combination therapy, which increases the risk of Drug-Related Problems (DRPs). This review aims to identify the types of DRPs, the most frequently implicated medications, causative factors, and pharmaceutical interventions based on various studies conducted in hypertensive patients. The literature review results indicate that common DRPs include drug interactions, ineffective therapy, the need for additional therapy, adverse drug reactions (ADRs), and inappropriate medication selection. Amlodipine, candesartan, valsartan, beta-blockers, and diuretics are among the medications most frequently associated with DRPs. Polypharmacy, non-adherence, comorbidities, and inadequate monitoring are the main contributing factors. Pharmaceutical interventions such as medication review, therapy monitoring, patient counseling, and adherence to clinical guidelines have been shown to be effective in reducing DRPs. The role of pharmacists is crucial to ensure the safety and effectiveness of hypertension therapy.
Efektivitas Penggunaan Obat Golongan Statin terhadap Pasien Penyakit Jantung Koroner Puji Elok Dzakirah; Karlina Dwi Febrianingsih; Baiq Haura Audina Ananta Putri; Khairinna Rifa Andira; Nanda Putri Utami Aziz; Sabila Rosyada; Tuhfatul Ulya
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 5 (2026): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i5.2373

Abstract

Coronary heart disease (CHD) is one of the leading causes of mortality worldwide and is closely associated with dyslipidemia, particularly elevated low-density lipoprotein (LDL) levels. Statins are recommended as first-line therapy to reduce LDL levels and lower the risk of cardiovascular events in patients with CHD. This literature review aimed to evaluate the effectiveness of statin therapy in patients with coronary heart disease. A literature search was conducted using Google Scholar between May 14 and May 29, 2025, with the keywords "statin drugs," "statin effectiveness," "coronary heart disease," and "LDL reduction." Articles were selected based on predetermined inclusion and exclusion criteria, resulting in ten eligible studies. The review showed that atorvastatin was the most frequently prescribed statin and consistently demonstrated effectiveness in reducing LDL levels by approximately 30–50%, increasing HDL levels, and lowering cardiovascular risk. Simvastatin was also effective in managing dyslipidemia, although several studies reported lower effectiveness compared with atorvastatin. Furthermore, a combination of rosuvastatin 10 mg and ezetimibe 10 mg was reported to be more effective in achieving LDL-C targets than high-intensity statin monotherapy in patients at very high cardiovascular risk. Overall, statins are effective for the management of coronary heart disease, with atorvastatin showing the most consistent therapeutic benefits.
Review Artikel: Drug Related Problems pada Penyakit Kronis: Implikasi Klinis dan Upaya Intervensi Nadira Khaerunnisa; Wulan Desi Rahmayanti; Anisa Zanuba; Zilfia Rahayu; Ditha Zanetti Octavia; Tuhfatul Ulya
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2720

Abstract

Chronic diseases such as type 2 diabetes mellitus, hypertension, asthma, and chronic kidney disease require long-term therapy that often involves multiple medications, increasing the risk of Drug Related Problems (DRPs). This review article summarizes patterns of DRPs and the contributing factors based on recent studies. The findings indicate that common DRPs include inappropriate dosing, drug interactions, drug use without indication, untreated indications, and ineffective therapy. In chronic kidney disease, DRPs frequently arise from inadequate dose adjustment in response to declining renal function, while in asthma, suboptimal medication use and incorrect inhaler technique are dominant causes. Overall, DRPs negatively affect therapeutic outcomes, increase the incidence of adverse effects, and elevate the risk of complications. Therefore, pharmacist-led interventions such as regular medication reviews, counseling, dose adjustment, and patient education are essential to prevent DRPs and improve treatment safety and effectiveness in chronic disease management.
Peningkatan Resistensi Antibiotik Clarithromycin dan Metronidazole terhadap Helicobacter pylori dan Tinjauan Implikasinya terhadap Terapi Peptic Ulcer Disease Salsabila Salsabila; Ni Putu Widiadnyani Putri; Keisha Andini Sakina; Riesky Maulani; Mufida Lisya Fatiha; Tuhfatul Ulya
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1257

Abstract

Peptic Ulcer Disease (PUD) remains a significant global health problem, with a substantial proportion of cases associated with Helicobacter pylori infection. The success of eradication therapy depends largely on antibiotic effectiveness, particularly that of clarithromycin and metronidazole. However, increasing H. pylori resistance to these antibiotics has become a major challenge, leading to treatment failure and reduced eradication rates. This review aims to examine current H. pylori resistance patterns to clarithromycin and metronidazole and their implications for eradication therapy. Evidence from various studies indicates that clarithromycin resistance reduces the efficacy of standard triple therapy consisting of a proton pump inhibitor (PPI), clarithromycin, and either amoxicillin or metronidazole. Metronidazole resistance also contributes to eradication failure, although its impact may be partially overcome by adjusting the dose or extending treatment duration. Therefore, therapeutic regimens should be selected based on local resistance patterns and rational antibiotic use. Alternative regimens, such as bismuth-based quadruple therapy, may be considered in regions with high resistance rates. Continuous surveillance of H. pylori antibiotic resistance is essential to improve eradication success and clinical outcomes in patients with PUD.