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Fitroh Bawa Berkah
Department of Industrial Technology, Vocational College, Universitas Diponegoro, Jalan Gubernur Mochtar, 50275 Semarang
Engineering

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Multi-Response Optimization of Mangosteen Peel Extraction Using Natural Deep Eutectic Solvent and Microwave Assisted Extraction for Anti-Aging Fitroh Bawa Berkah; Vita Paramita
Journal of Vocational Studies on Applied Research 2025: JVSAR, Volume 7 Issue 1 Year 2025 (April 2025)
Publisher : Vocational College of Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jvsar.v7i1.26555

Abstract

The peel of mangosteen (Garcinia mangostana L.) is rich in bioactive compounds, including xanthones, phenolics, flavonoids, anthocyanins, and vitamin C, which have been associated with antioxidant, anti-inflammatory, and anti-aging properties. This study aimed to optimize the extraction of these compounds, particularly xanthones, using Microwave-Assisted Extraction (MAE) in combination with a Natural Deep Eutectic Solvent (NADES) consisting of lactic acid, sodium acetate, and distilled water in a 3:1:2 volume ratio. The extraction process was carried out under varying microwave power levels (300, 375, and 450 Watt) and extraction times (2, 4, and 6 min). Optimization was conducted using Response Surface Methodology (RSM), and the resulting bioactive compound contents were analyzed by UV-Vis spectrophotometry. The optimal extraction conditions were determined at 300 Watt and 4.46 min, resulting in xanthone (1.40%), phenolics (42.43%), flavonoids (1.22%), anthocyanins (1.20%), and vitamin C (2.94%). These findings indicate that NADES-MAE is an effective green extraction technique for maximizing bioactive compounds from mangosteen peel, supporting its potential use in anti-aging product formulations.
Co-Authors Vita Paramita