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All Journal Medfarm: Jurnal Farmasi dan Kesehatan Mohuyula : Jurnal Pengabdian Kepada Masyarakat
Rosida Rosida
Politeknik Kesehatan Jember
Chemistry Medicine & Pharmacology Public Health Other

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Penguatan Upaya Preventif Penyakit Degeneratif Melalui Pemeriksaan Kesehatan Lansia Bersama PIP3T di Desa Sumberjeruk Denok Risky Ayu Paramita; Rosida Rosida; Alfi Rizqi Oktafi Rohmadoni; Aninda Nyoka Sari; Septiana Bintang Maharani
Mohuyula : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 1 (2026): Juni
Publisher : Universitas Muhammadiyah Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31314/mohuyula.5.1.27-35.2026

Abstract

Meningkatnya proporsi penduduk lanjut usia (lansia) berdampak pada tingginya prevalensi penyakit degeneratif, seperti hipertensi dan diabetes melitus, yang menjadi penyebab utama morbiditas dan mortalitas pada kelompok usia tersebut. Pengabdian kepada masyarakat ini bertujuan mendukung upaya preventif penyakit degeneratif melalui pemeriksaan kesehatan dasar dan edukasi kesehatan bersama PIP3T (Pusat Informasi dan Pelatihan Pencegahan Penyakit Tropis) di Posyandu Lansia Teratai 1, Desa Sumberjeruk, Kabupaten Bondowoso. Sebanyak 21 peserta yang terdiri atas masyarakat lansia mengikuti pengukuran tekanan darah, pemeriksaan kadar gula darah sewaktu, sosialisasi penyakit degeneratif, edukasi pola hidup sehat, serta konsultasi hasil pemeriksaan. Hasil skrining memberikan gambaran awal mengenai kondisi kesehatan peserta, dengan beberapa peserta memiliki tekanan darah sistolik ≥140 mmHg atau diastolik ≥90 mmHg, bahkan mencapai 200/109 mmHg, serta kadar gula darah sewaktu tertinggi sebesar 187 mg/dL. Selama pelaksanaan kegiatan, peserta berpartisipasi aktif dalam sesi edukasi, diskusi, dan konsultasi kesehatan. Hal ini menunjukkan bahwa skrining kesehatan yang dipadukan dengan edukasi dapat menyediakan informasi awal mengenai faktor risiko penyakit degeneratif sekaligus mendukung upaya deteksi dini di masyarakat. Selain itu, kegiatan ini mendukung peran kader kesehatan dalam pemantauan kesehatan masyarakat melalui Posyandu Lansia dan program PIP3T secara berkelanjutan.
Analgesic Effectiveness Study Of N-4t-Butylbenzoyl Acetate Compound In Male Balb-C Strain Mice Hadi Barru Hakam Fajar Siddiq; Rosida Rosida; Dewi Riskha Nurmalasari; Resa Try Afriani; Yuriko Titan Yanindra
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.591

Abstract

This study aims to understand the activity and effective dose of N-4t-butylbenzoyl Acetate compound as a pain reliever. The analgesic activity test conducted was divided into 5 treatment groups. The analgesic effect test was performed using male mice from the Balb-C strain. In each test, each group consisted of 5 experimental animals. The first group (negative control) was given 1% Na-CMC suspension; the second group (positive control) received 400 mg/kgBW ibuprofen; while the third, fourth, and fifth groups were successively given 200, 400, and 600 mg/kgBW of N-4t-butylbenzoyl Acetate compound, respectively. After the treatment was given to each test animal, an analgesic test was conducted with a 30-minute interval. After that, it was injected with 1% acetic acid and observed for 180 minutes; every 10 minutes, the movement was observed for all treatments. The analysis was carried out by comparing the number of movements (writing reflex). Data analysis was performed statistically using ANOVA (analysis of variance). The number of mouse activities produced by male mice of the Balb-C strain showed that the N-4t-butylbenzoyl acetate compound at a dose of 1.56 mg had the highest activity, % protection, and % analgesic effectiveness compared to the other two doses. Based on statistical analysis, there was no significant difference in all treatments of the N-4t-butylbenzoyl acetate compound when compared to ibuprofen (positive control)
Co-Authors Alfi Rizqi Oktafi Rohmadoni Aninda Nyoka Sari Denok Risky Ayu Paramita Dewi Riskha Nurmalasari Hadi Barru Hakam Fajar Siddiq Resa Try Afriani Septiana Bintang Maharani Yuriko Titan Yanindra