The phenomenon of increased emotional sensitivity in adolescents, which is not always balanced with the ability to manage internal experiences, indicates a potential imbalance between empathy and mindfulness in everyday life. Adolescence is an important phase in the formation of self-identity, where the ability to manage internal experiences and emotional responses becomes crucial. Mindfulness plays a role in maintaining emotional balance and the quality of interpersonal relationships, while empathy is the basis for healthy social interactions. This study aims to analyze the relationship between empathy and mindfulness in vocational high school students in Yogyakarta. Using a correlational quantitative approach, the study involved 147 students selected through random sampling. The instruments used were the Empathy Quotient (EQ-40) and the Child and Adolescent Mindfulness Measure (CAMM), which have been tested for validity and reliability. The results of the Pearson Product Moment analysis show a significant negative relationship between empathy and all aspects of mindfulness, namely awareness (r = –.686, p < .01), attention (r = –.620, p < .01), nonjudgmentally (r = –.821, p < .01), and mindfulness as a whole (r = –.212, p < .05). These findings indicate that high empathy may be associated with low mindfulness due to empathic distress, thus emphasizing the importance of strengthening emotional regulation and mindfulness skills so that empathy continues to develop adaptively in adolescents. Further research is recommended using a more controlled methodological approach to capture the complexity of the relationship between empathy and mindfulness in adolescents.