Luh Santhi Utami Wiryani
Universitas Mahasaraswati Denpasar

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The Relationship Between Knowledge Level and Attitudes of the Sanding Gianyar Community Toward the Use of Traditional Medicines for Self-Medication Fitria Megawati; Ni Putu Dewi Agustini; Luh Santhi Utami Wiryani
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/c9grej48

Abstract

Background: Knowledge is defined as an individual's ability that serves as the basis for decision-making and can influence attitudes. The self-medication process often involves the use of traditional medicine, where its utilization is strongly influenced by the individual's level of knowledge and attitude. Objective: This study aims to determine the relationship between the level of knowledge and community attitudes toward the use of traditional medicine for self-medication in Banjar Dinas Sanding, Gianyar. Methods: This study used a cross-sectional research design with an accidental sampling technique. The sample size was determined using the Slovin formula, resulting in 247 respondents from a population of 649 people who met the inclusion and exclusion criteria. The data used were primary data collected through questionnaires, consisting of a knowledge questionnaire using the Guttman scale and an attitude questionnaire using the Likert scale. Results: Data analysis in this study was conducted using univariate and bivariate analyses. The results showed that in the knowledge aspect, 153 respondents (61.94%) had good knowledge, while 94 respondents (38.06%) had poor knowledge. In the attitude aspect, 152 respondents (61.55%) showed a positive attitude, while 95 respondents (38.46%) had a negative attitude. The analysis of the influence of knowledge level on community attitudes was performed using SPSS with the Chi-Square test, which produced a p-value of 0.001 (p < 0.05).Conclusion: There was a significant relationship between the level of knowledge and attitudes toward the use of traditional medicine in Banjar Dinas Sanding, Gianyar.
Analysis of Drug Use and Potential Interactions in Type 2 Diabetes Inpatients at a Type C Hospital, Kediri (2024) anis akhwan dhafin; Luh Santhi Utami Wiryani; Elsa Mahardika Putri; Herman Herman; Pulung Prabowo; Prayoga Feri Yuniarto; Winartiana Winartiana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.641

Abstract

Bachelor of Pharmacy, Universitas Mahasaraswati Denpasar, Indonesia Corresponding Author: anisdhafin13@unik-kediri.ac.id ABSTRACT Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a high prevalence and frequent comorbidities, particularly hypertension, which often require multidrug therapy and increase the risk of drug interactions. This study aimed to analyze the pattern of antidiabetic drug use and the potential for drug interactions in hospitalized patients with T2DM at a type C hospital in Kediri City during June–December 2024. The research employed a retrospective descriptive design using medical record data of 44 patients who met the inclusion criteria. Data were analyzed descriptively and presented in frequency distribution tables. Results showed that the most commonly prescribed drug class was biguanides (26.25%), followed by sulfonylureas (21%), insulin (21%), and α-glucosidase inhibitors (12.5%). Combination therapy was widely used, particularly the combination of two oral antidiabetic agents. Potential drug interactions were identified in 72.73% of patients, with moderate interactions being the most frequent (78.13%), followed by minor (12.5%) and major (9.38%) interactions. The most common interactions included metformin with amlodipine or ramipril (moderate severity), captopril with hydrochlorothiazide (minor severity), and simvastatin with amlodipine (major severity). However, in this study polypharmacy was defined as the concomitant use of ≥5 medications. These findings indicate that such polypharmacy in T2DM patients with hypertension substantially increases the likelihood of drug interactions, underscoring the importance of careful monitoring and rational prescribing to improve patient safety
Cost Minimization Analysis of Antibiotic Drug Use in Pneumonia Patients at Udayana Class II Hospital Luh Santhi Utami Wiryani; Fitria Megawati; I Dewa Agung Ayu Diva Candraningrat
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.655

Abstract

Pneumonia is one of the leading causes of morbidity and mortality in Indonesia, with a high economic burden mainly due to antibiotic use, which consumes a large portion of hospital budgets. This study aimed to analyze the cost-minimization of antibiotic therapy in hospitalized pneumonia patients at Tk II Udayana Hospital. A descriptive non-experimental retrospective study was conducted using medical records of pneumonia inpatients at Tk.II Udayana Hospital from January to December 2023. A total of 138 patients met the inclusion criteria. Data analyzed included demographics, length of stay, and direct medical costs. Cost minimization analysis was performed by comparing the average direct medical costs of each antibiotic therapy. Of 233 medical records screened, only 138 fulfilled the criteria. Male patients (53.6%) were slightly more than females (46.4%), with the majority aged 1–5 years (64.5%). Most patients had a length of stay of 1–7 days (99.3%). Antibiotics used included Ceftriaxone, Cefotaxime, Azithromycin, Cefoperazone, and Cefixime (monotherapy or combination). The highest direct medical cost was found in Ceftriaxone monotherapy (IDR 1,973,061 ± 393,521), while the lowest was in Cefixime monotherapy (IDR 1,574,659 ± 39,208). Statistical analysis using the Mann-Whitney test showed no significant difference in costs based on the length of stay (p=0.123). Cefixime monotherapy was the most cost-minimization therapy for pneumonia inpatients at Tk.II Udayana Hospital, with equal clinical effectiveness but lower costs compared to other therapies. This finding may serve as a consideration for hospital formulary development to improve budget efficiency without compromising quality of care.