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All Journal JFL : Jurnal Farmasi Lampung Borneo Journal of Biology Education (BJBE)
Mastuti Widianingsih
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Malahayati
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

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POTENSI LIMBAH TANGKAI BUAH CABAI RAWIT DAN CABAI MERAH KERITING SEBAGAI BIOINSEKTISIDA NYAMUK Aedes aegypti: POTENTIAL OF BIRD'S EYE CHILI AND RED CURLY CHILI STEM WASTE AS A BIOINSECTICIDE FOR Aedes aegypti Fadilla Amelia Riski; Dwi Susanti; Mastuti Widianingsih
JFL : Jurnal Farmasi Lampung Vol. 15 No. 1 (2026): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/665das65

Abstract

Abstract The stems of bird's eye chili (Capsicum frutescens L.) and curly red chili (Capsicum annuum L.), which are typically considered waste, actually hold compounds with potential for biological activity. Phytochemical screening has shown that stems of bird’s eye chili contain secondary metabolites such as alkaloids, phenolics, tannins, flavonoids, terpenoids, and saponins, while curly red chili stems contain alkaloids, steroids, phenolics, tannins, flavonoids, and saponins. The objective of this research to evaluate the effectiveness and determine the optimal concentration of both extracts as bioinsecticides against Aedes aegypti mosquitoes. Extraction was performed by maceration using 96% ethanol (ratio simplicial:solvent=1:10). The yield of bird’s eye chili extract was 7.45%, while curly red chili extract of 8.06%. The experiment consisted of five treatment groups with extract concentrations of 1%, 3%, and 5%; transfluthrin as a positive control; and distilled water as a negative control. Each group contained 25 Aedes aegypti mosquitoes. Mortality result indicated that both extracts had bioinsecticidal activity, although their effectiveness varied at different concentrations. The stems of bird’s eye chili extract showed the greatest effect at 5% concentration, with an LC₅₀ value of 4,177% at the 4th hour, while the curly red chili stems extract was most effective at 5% concentration, with an LC₅₀ value of 4,048% at the 5th hour. In conclusion, chili stem waste extracts demonstrate promising potential as effective and environmentally friendly botanical bioinsecticides for controlling Aedes aegypti. Keywords: Aedes aegypti, Bioinsecticide, Curly Red Chili, Chili Stem Waste
Narrative Literature Review : Aktivitas Antibakteri Daun Kopi Robusta (Coffea canephora Pierre ex A.Froehne) Mastuti Widianingsih
Borneo Journal of Biology Education (BJBE) Vol. 8 No. 1 (2026): April
Publisher : Department of Biology Education, Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/tma5mt51

Abstract

Meningkatnya resistensi antibiotik mendorong pencarian agen antibakteri alami yang efektif dan aman. Daun kopi robusta (Coffea canephora) mengandung berbagai metabolit sekunder seperti flavonoid, tanin, alkaloid, saponin, polifenol, dan triterpenoid yang berpotensi memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengkaji secara naratif bukti ilmiah terkait aktivitas antibakteri daun kopi robusta, mekanisme kerja, serta faktor-faktor yang mempengaruhi efektivitasnya. Metode yang digunakan adalah narrative literature review melalui penelusuran literatur pada Google Scholar dalam rentang tahun 2016-2026. Seleksi dilakukan melalui tahapan identifikasi, screening, dan full-text review sesuai kriteria yang ditetapkan, sehingga diperoleh 17 artikel yang dianalisis secara deskriptif. Hasil menunjukkan bahwa ekstrak daun kopi robusta memiliki aktivitas antibakteri terhadap bakteri Gram-positif dan Gram-negatif, termasuk Staphylococcus aureus, Escherichia coli, Propionibacterium acnes, Streptococcus mutans, serta MRSA. Mekanisme meliputi kerusakan membran sel, penghambatan sintesis dinding sel dan protein, gangguan enzim, serta hambatan pembentukan biofilm. Aktivitasnya dipengaruhi oleh metode dan pelarut ekstraksi, kondisi pengolahan, konsentrasi, dan formulasi. Secara keseluruhan, daun kopi robusta berpotensi sebagai kandidat fitofarmaka dan bahan aktif produk farmasi maupun kosmetik, namun masih diperlukan penelitian in vivo dan uji klinis untuk memastikan keamanan dan efektivitasnya.
Co-Authors Dwi Susanti Fadilla Amelia Riski