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All Journal JOPS (Journal Of Pharmacy and Science) Jurnal Farmasi Indonesia
Najmi Hilaliyati
Universitas Muhammadiyah Riau
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hipertensi sebagai Prediktor Luaran Klinis pada Pasien COVID-19 pasien Rawat Inap: Studi di Rumah Sakit Achmad Mochtar Najmi Hilaliyati; Reza Laila Najmi; Efilia Meirita; Izza Aulia Rizqika Nasution; Fitratul Wahyuni; Resi Rizki Banjarani
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.7009

Abstract

Populations with comorbidities, especially hypertension, are susceptible to COVID-19 infection and are known to be at risk of increasing disease severity, increasing the risk of poor clinical outcomes, and high mortality. There is no specific therapy to treat this disease, but several types of antivirals have been developed. The purpose of this study was to study the impact of comorbidities and antiviral therapy on clinical outcomes in the form of a length of stay and vital signs (pulse, respiratory rate, temperature, and oxygen saturation) of COVID-19 patients with or without comorbid hypertension. The study was conducted with a cross-sectional design. Data were collected retrospectively through the medical records of 80 patients who met the inclusion criteria and were treated during the period April 2020–March 2021 at Bukittinggi Hospital. Data were analyzed using the Mann-Whitney U Test, Kruskal Wallis Test, Friedman Test, and Repeated Measures Anova. The results showed that comorbidity had a significant impact on the patient's respiratory rate (p<0.05). The administration of different antivirals in patients with or without comorbid hypertension had a significant impact on the length of stay, body temperature, and oxygen saturation of patients (p<0.05). Patients receiving favipiravir therapy showed a shorter length of stay than the antivirals Oseltamivir, Ramdesivir and Hydroxychloroquine.
17-2 Variasi Penggunaan Beeswax Lip Balm Stik dari Ekstrak Kulit Nanas (Ananas comosus (L.) Merr.) Najmi Hilaliyati; Resi Rizki Banjarani; Muhammad Arif; Nursyafni; Widiya Ismail
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.872

Abstract

Lip balm is a preparation applied to the lips to prevent dryness and chapping. Choosing the right lip balm base will significantly impact its quality and public acceptability. Beeswax has good binding properties, which help to produce a homogeneous mass. In this study, the active ingredient used was pineapple peel because it contains bromelain, which moisturizes the lips. The objectives of this study were to determine the appropriate formulation for lip balm preparations with pineapple peel extract (Ananas comosus (L.) Merr.) as the active ingredient and to determine the effect of varying beeswax base concentrations on the physical stability of lip balm preparations. The method used in this study was an experimental method to see which formulation was suitable. The study obtained a good formula with physical characteristics in accordance with SNI 16-4769-1998, including stability observation, pH measurement, homogeneity testing, irritation testing, moisture testing, and cycling test. The appropriate formula was found in formula 1 with a beeswax concentration of 1%, which produced a good color texture, aroma, adhesive power, and spreadability, a pH level suitable for the lips, no irritation, homogeneity, and stability during storage, resulting in a semi-solid and very smooth lip balm texture when used
Co-Authors Efilia Meirita Fitratul Wahyuni Izza Aulia Rizqika Nasution Muhammad Arif Nursyafni Resi Rizki Banjarani Resi Rizki Banjarani Reza Laila Najmi Widiya Ismail