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All Journal Jurnal Surya Medika Klinikal Sains (Jurnal Analis Kesehatan)
Novamei Indriani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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ANALISIS PERBANDINGAN KADAR FLAVONOID TOTAL TEH HIJAU DAN TEH HITAM DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Antonia Vani Kurniawati; .A.K Pramushinta; A.S. Sinulingga; Novamei Indriani
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 2 (2024): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i2.4986

Abstract

Tea leaves (Camellia sinensis) are a functional plant that is useful for preventing cancer, maintaining immunity and preventing premature aging. Flavonoids are one of the largest groups of polyphenols which are active compounds from tea leaves (Camellia sinensis). This study aims to determine the total flavonoid content of green tea leaf extract and black tea leaf extract using 2 extraction methods, namely maceration with 96% ethanol solvent and infusion using water solvent. The method in this research uses qualitative tests (Wilstarter cyanidin and NaOH 10%) and quantitative tests (UV-Vis Spectrophometry) and conclusions will be drawn using the SPSS statistical test T (independent)-test. The results of the qualitative test using the starter cyanidin and 10% NaOH were positive for containing flavonoids due to a reddish color change. In the quantitative test, the assay was carried out using UV-Vis spectrophotometry with a wavelength of 434 nm. In this study, the total flavonoid content obtained in the green tea maceration method was 15.728% w/w ± 0.209, black tea maceration 13.357% w/w ± 0.737, green tea infusion 4.153% w/w ± 0.124 and black tea infusion 3.320% w /b ± 0.352. There is a significant difference between green tea and black tea using both the infusion and maceration methods as shown by a sig value ≤ 0.05.
Studi Penggunaan Obat Pada Pasien Sindrom Ovarium Polikistik (Pcos) Di Rsud Haji Provinsi Jawa Timur Shella Anggraini; Asri Wido Mukti; Novamei Indriani; Rosy Nurlita Hapsari
Jurnal Surya Medika (JSM) Vol. 12 No. 2 (2026): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v12i2.13547

Abstract

Polycystic Ovary Syndrome (PCOS) is the most common endocrine-metabolic disorder among women of reproductive age, yet comprehensive data on its drug utilization pattern in Indonesian regional hospitals remain limited, particularly in East Java. This study aimed to describe the drug utilization pattern in PCOS patients at RSUD Haji East Java Province during 2020-2025. A descriptive retrospective design was applied using total sampling of 57 outpatient medical records meeting the inclusion criteria, analyzed descriptively using Microsoft Excel. Results showed that monotherapy was the predominant treatment pattern (70.2%), with hormonal therapy being the most frequently used drug class (78.9%). The most commonly prescribed drugs were norethisterone 5 mg (43.9%) and Cycloprogynova (40.4%), while metformin was used in 14.0% of patients and clomiphene citrate (Diphten) as an ovulation-inducing agent in 12.3% of patients. Doses and frequencies were mostly consistent with standard literature, with two frequency variations found for Diane 35 and Microgynon, reflecting the prescribing physician's clinical judgment. Documented adverse effects were found in only one patient (1.8%), consisting of dizziness potentially associated with metformin. All patients (100%) showed clinical improvement in the form of menstrual return within 2 to 6 days after therapy. It is concluded that PCOS drug utilization at RSUD Haji is dominated by hormonal therapy with favorable clinical response, although the completeness of medical record documentation should be improved to support comprehensive therapy monitoring.
Co-Authors .A.K Pramushinta A.S. Sinulingga Antonia Vani Kurniawati Mukti, Asri Wido Rosy Nurlita Hapsari Shella Anggraini