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All Journal Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Rahma Yulina Al-Farini
Unknown Affiliation
Medicine & Pharmacology Nursing Public Health

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Evaluasi Formulasi Sediaan Floating Mikroenkapsulasi yang Mengandung Ekstrak Etanol Daun Salam (Syzygium Polyanthum) Rahma Yulina Al-Farini; Razoki Razoki; Muhammad Yunus; Hariyadi Dharmawan Syahputra
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 4 No. 1 (2025): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v4i1.4894

Abstract

Ethanol extract of bay leaves is known to have pharmacological activities such as anti-inflammatory, antihypertensive, and antidiabetic. However, its stability and solubility are still challenges. Therefore, a microencapsulation-based delivery system with floating characteristics that can last longer in the stomach was developed. This study aims to evaluate floating microencapsulation preparations containing ethanol extract of bay leaves (Syzygium polyanthum) as an effort to increase the effectiveness and bioavailability of active substances orally. The results showed that microencapsulation had a total floating of more than 4 hours with a water content of 0.47% -2.14%. Stability tests showed no significant changes in physical and chemical characteristics after cycling tests.
Co-Authors Hariyadi Dharmawan Syahputra Muhammad Yunus Razoki Razoki