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All Journal Jurnal Surya Medika Jurnal Kesehatan Saintika Meditory
Uli Masuliyah Indarwati
Universitas Muhammadiyah Purwokerto
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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IMMATURE PLATELET FRACTION (IPF) EXAMINATION IN DENGUE FEVER: LITERATURE REVIEW Uli Masuliyah Indarwati; Defi Nurul Hayati
Jurnal Kesehatan Saintika Meditory Vol 8, No 2 (2025): November 2025
Publisher : STIKES Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v8i2.30597

Abstract

Dengue Fever occurs in patients with varying degrees of severity. One of the symptoms that may appear is thrombocytopenia, which is characterized by a low platelet count. Therefore, it requires special attention in laboratory examinations. The Immature Platelet Fraction (IPF) is one of the hematology test parameters that has potential as a supporting parameter for platelet examination. Evaluation of the IPF value in laboratory tests contributes to the differential diagnosis of thrombocytopenia cases. The purpose of this literature review is to identify the IPF examination in laboratory and to describe the IPF profile in DHF cases. The search method was conducted through PubMed, Google Scholar, and Scopus, with articles reviewed from the years 2016 to 2025. Based on the literature review, IPF examination can be performed using a hematology analyzer. The IPF parameter has an inverse relationship with the platelet parameter increase in IPF value occurs alongside a decrease in platelet count.Conclusion: The IPF parameter can be considered a supporting parameter for platelet examination, for monitoring the severity of thrombocytopenia, and as a predictor of platelet recovery
Hubungan Antara Kadar Procalcitonin dengan Jumlah Leukosit pada Penderita Diabetes Melitus Pasca Terapi Bekam Basah: The Correlation between Procalcitonin Levels And Leukocyte Counts In Patients with Diabetes Mellitus After Wet Cupping Therapy ANNISA SHOFIA FAJRO; DITA PRATIWI KUSUMA WARDANI; ULI MASULIYAH INDARWATI; RETNO SULISTIYOWATI; KURNIA RITMA DHANTI
Jurnal Surya Medika (JSM) Vol. 12 No. 1 (2026): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v12i1.12484

Abstract

Diabetes melitus merupakan gangguan metabolik kompleks yang ditandai hiperglikemia dan melibatkan disfungsi multiorgan, termasuk sel β pankreas, jaringan adiposa, otot rangka, dan hati. Penderita diabetes melitus diketahui memiliki risiko infeksi yang lebih tinggi daripada pasien non-diabetes akibat gangguan sistem imun dan kondisi inflamasi kronis. Procalcitonin merupakan biomerker yang meningkat pada infeksi bakteri/sepsis dan digunakan sebagai indikator inflamasi sistemik, sementara leukosit mencerminkan respon imun seluler terhadap proses inflamasi dan infeksi. Kedua parameter ini dapat memberikan gambaran kondisi inflamasi pada penderita DM. Selain itu terapi komplementer seperti bekam basah telah digunakan lama dan diyakini memiliki efek terhadap perbaikan sirkulasi darah dan respon imun. Tujuan penelitian ini untuk mengetahui hubungan antara kadar procalcitonin dengan jumlah leukosit pada penderita diabetes melitus pasca terapi bekam basah. Penelitian ini berjenis quasi-experimental dengan rancangan one group posttest only design yang melibatkan 22 orang penderita DM tipe 2 yang menjalani terapi bekam basah. Data kadar procalcitonin dan jumlah leukosit dianalisis dengan uji korelasi Spearman’s rho. Hasil uji korelasi Spearman’s rho menunjukkan nilai p = 0.635 dan nilai r = 0.107. Tidak terdapat hubungan kadar procalcitonin dengan jumlah leukosit pada pasien DM tipe 2 pasca terapi bekam basah.
Co-Authors ANNISA SHOFIA FAJRO Defi Nurul Hayati Dhanti, Kurnia Ritma Dita Pratiwi Kusuma Wardani Retno Sulistiyowati