Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Journal of Biomedical and Techno Nanomaterials
Lidiya Fatmaningsih
Institut Agama Islam Negeri Kediri
Biochemistry, Genetics & Molecular Biology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Differences in the Life Cycle and Growth of Plasmodium Knowlesi, Inui, Vivax, Malariae, Falciparum, Ovale Lidiya Fatmaningsih; Nadia Azhar Samasta; Linda Octa
Journal of Biomedical and Techno Nanomaterials Vol. 1 No. 2 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v1i2.1020

Abstract

Plasmodium is a parasite that causes malaria in humans. Various Plasmodium species have differences in their life cycles and growth, which influence the clinical characteristics and management of malaria. This article explains the differences in the life and growth cycles of the six Plasmodium species most commonly found in humans, namely Plasmodium knowlesi, Plasmodium inui, Plasmodium vivax, Plasmodium malariae, Plasmodium falciparum, and Plasmodium ovale. Each species has differences in its life cycle, including pre-erythrocytic, erythrocytic, and extracellular duration. In addition, these differences also influence clinical symptoms, disease severity, and response to treatment. A thorough understanding of these differences is important for accurate diagnosis and effective treatment of malaria.
Genetic Engineering of Mosquitoes Causes Malaria Nur Afni Maulina Maghfiro; Lidiya Fatmaningsih; Maulidatul Aulia; Ibrahim Bin Said
Journal of Biomedical and Techno Nanomaterials Vol. 1 No. 2 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v1i2.1025

Abstract

Malaria is still a health problem in the world and in Indonesia in particular. Malaria vector control is an important strategy in efforts to control and eliminate malaria because it is very effective in preventing infection and reducing disease transmission. The CRISPR/Casnuclease system is a potent new genome editing system and tool for species-specific diagnosis, drug resistance research for Plasmodium species, and gene driver for Anopheles population control, according to an assessment of earlier genome editimg techniques. This Anopheles mosquito CRISPR/Cas9 technique on plasmodium has been applied in research to detect malaria parasites by inhibiting their growth throughout the life cycle, allowing evaluation of the effectiveness of antimalarial drugs or vaccines at various stages of the parasite life cycle. In addition, CRISPR/Cas9 in Anopheles mosquitoes allows identification and double-strand breaks in target DNA, which can then be modified through genome changes. So, with the development of gene editing technology, the spread of Anopheles mosquitoes can be controlled and reduced.
Co-Authors Ibrahim Bin Said Linda Octa Maulidatul Aulia Nadia Azhar Samasta Nur Afni Maulina Maghfiro