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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Sains Medisina International Journal of Health Systems and Policy
Dwi Ismayati
Universitas Lampung
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Profile Of Patient Diagnosed With Depression In Bandar Lampung In 2023 (BPJS Kesehatan Sample Data From 2024): A Descriptive Study Syaripah Ulandari; Yulianasari Pulungan; Dwi Ismayati; Made Laksmi Meiliana
International Journal of Health Systems and Policy Vol. 2 No. 1 (2026): Vol 2 No 1 June 2026
Publisher : Ponpes As-Salafiyyah Asy-Syafi'iyyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71305/ijhsp.v2i1.1622

Abstract

Depression is a major global public health concern and a leading cause of disability worldwide, affecting individuals across various demographic groups. Despite its high burden, local descriptive data on depression remain limited, particularly in Bandar Lampung. This study aims to describe the sociodemographic profile of patients diagnosed with depression in Bandar Lampung in 2023 using BPJS Kesehatan sample data. This study employed a descriptive, observational, cross-sectional design using secondary data from the 2023 BPJS Kesehatan dataset. The sample included patients diagnosed with depression based on ICD-10 codes F32 and F33 who accessed referral healthcare facilities (FKRTL). A total of 41 patients from Bandar Lampung were included after data cleaning. Descriptive statistical analysis was conducted to summarize patient characteristics, including diagnosis type, generation, gender, participant segmentation, marital status, and healthcare costs. The results showed that the most common diagnosis was unspecified depressive episode (F329) (31.71%). The majority of patients were from Generation Z (41.46%), female (85.37%), and formally employed participants (31.71%). Most patients were married (53.66%). The total healthcare cost for depression cases reached IDR 10,929,600. These findings highlight the predominance of depression among younger individuals, women, and working populations. In conclusion, depression in Bandar Lampung is influenced by demographic and socioeconomic factors, with higher prevalence observed among vulnerable groups such as Generation Z and women. These findings underscore the need for improved mental health screening, targeted interventions, and strengthened healthcare system support to address depression effectively. Further studies with larger, more comprehensive datasets are recommended.
Efficacy and Safety of Antihypertensive Drugs in Chronic Kidney Disease Patients at Menggala Regional General Hospital Denny Ardhianto; Made Laksmi Meiliana; Dwi Ismayati; Syaripah Ulandari; Okta Puspita; Rena Oktaviana
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 23 No. 1 (2026): Jurnal Ilmu Farmasi dan Farmasi Klinis (JIFFK)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v23i1.14983

Abstract

Chronic kidney disease (CKD) is a progressive condition characterized by a gradual decline in glomerular filtration rate, often accompanied by hypertension, necessitating antihypertensive therapy. This study aimed to evaluate the effectiveness of antihypertensive drugs in achieving blood pressure targets (<140/90 mmHg or a mean arterial pressure reduction of ≥20 mmHg) and to identify the incidence of adverse effects in CKD patients at Menggala Regional General Hospital during 2024. A retrospective observational study was conducted using medical records from 199 CKD inpatients selected via purposive sampling. Data analysis employed descriptive statistics, paired t-tests for effectiveness, and chi-square tests for associations between drug types. Results indicated that combination therapy with furosemide IV, candesartan, and amlodipine was the most common (77.4%) and demonstrated effectiveness in 50.8% of cases (p=0.01). Adverse effects occurred in only 1.0% of patients, primarily peripheral edema. The findings underscore the efficacy of combination therapies involving diuretics, ARBs, and CCBs in managing hypertension in CKD, with minimal adverse events. This research provides valuable insights for optimizing antihypertensive regimens in similar settings.
Analisis Efektivitas Biaya Terapi Antihipertensi pada Pasien Hipertensi dengan Penyakit Penyerta Diabetes Mellitus: narrative review Dwi Ismayati
Sains Medisina Vol 4 No 2 (2025): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i2.943

Abstract

Hipertensi merupakan tantangan kesehatan global dengan prevalensi yang terus meningkat, termasuk di Indonesia yang mencapai 34,1% pada tahun 2018. Hipertensi memberikan dampak pada kualitas hidup pasien dan beban ekonomi yang masif serta hilangnya produktivitas. Di Indonesia, hipertensi menempati urutan teratas pembiayaan kesehatan nasional mencapai Rp12,1 triliun. Artikel ini bertujuan untuk memberikan gambaran perbandingan Cost Effectiveness Analysis (CEA) terapi antihipertensi pada pasien hipertensi dengan komorbid diabetes mellitus. Penelitian ini menggunakan metode tinjauan pustaka naratif (narrative review). Sumber data diperoleh melalui penelusuran literatur ilmiah pada basis data PubMed, Google Scholar, dan ScienceDirect menggunakan kata kunci terkait. Dari 386 artikel yang teridentifikasi, terpilih 7 artikel yang memenuhi kriteria inklusi (artikel orisinal, full-text, dan relevan dengan komorbid DM) untuk dianalisis secara deskriptif. Hasil sintesis artikel menunjukkan variasi nilai ACER dan ICER. Monoterapi amlodipin menunjukkan efisiensi tinggi pada studi tertentu dengan ICER negatif. Pada terapi kombinasi, regimen ACEI-CCB dan ACEI-Diuretik Thiazide mendominasi sebagai pilihan paling cost-effective. Namun, studi lain juga menunjukkan keunggulan kombinasi CCB-ARB dibandingkan CCB-ACEI dalam hal efisiensi biaya. Penentuan terapi paling cost-effective bersifat spesifik tergantung regimen yang dibandingkan. Kesimpulan pada tinjauan ini menunjukkan bahwa secara umum, kombinasi ACEI-CCB dan ACEI-Thiazide memberikan keseimbangan optimal antara biaya dan efektivitas klinis. Nilai ICER negatif pada beberapa studi menandakan potensi penghematan biaya (cost-saving) yang signifikan dalam manajemen hipertensi-diabetes.
Co-Authors Denny Ardhianto Made Laksmi Meiliana Okta Puspita Rena Oktaviana Syaripah Ulandari Yulianasari Pulungan