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All Journal Jurnal Sain Veteriner Jurnal Teknosains ARSHI Veterinary Letters
Dinar Arifianto
Departemen Patologi Klinik, Fakultas Kedokteran Hewan, Universitas Gadjah Mada Yogyakarta, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Industrial & Manufacturing Engineering Mechanical Engineering Veterinary

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Kajian Kliniko-patologik dan Antimikroba Ekstrak Biji Alpukat (Persea Americana Mill) Christin Marganingsih Santosa; Imron Rosyadi; Dinar Arifianto; Salasia Isrina Oktavia Siti
Jurnal Sain Veteriner Vol 37, No 2 (2019): Desember
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.715 KB) | DOI: 10.22146/jsv.40445

Abstract

The phytochemical components of avocado seeds (Persea americana Mill) consist of alkaloids, flavonoids, tannins and saponins, so that they have the potential as antibacterials. The aim of this study was to determine the ability of Persea americana Mill extract to inhibit the growth of Staphylococcus aureus through inhibition zone observation and the ability to accelerate wound healing infected by S. aureus through observation of wound closure and cytopathology.  Persea americana Mill were extracted using maceration method with 70% ethanol. The activities of this extract were tested by diffusion disc agar method. Biomedical tests were carried out on anaestetic Wistar rats whose were S. aureus infected wounds  and treated with Persea Americana Mill extract. Based on the results of the antimicrobial test, avocado seed extract has a inhibitory effect on the growth of S. aureus at a concentration of 6.25% and best at a concentration of 100% compared to the control. Tests in experimental rats showed the effect of wound healing on the 2rd day after giving the extract Persea americana Mill ointment, faster than the control, which was need 4 days of wound closure. Cytopathology results showed that leukocyte activity was more prominent in rats treated with avocado seed extract compared to control rats. Avocado seeds as byproducts have the potential to be new herbal medicines that can be used as antimicrobials of S. aureus which have been confirmed to be resistant to various antibiotics.
Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus) Widowati Siswomihardjo; Dyah Anindya Widyasrini; Dinar Arifianto; Setyo Budhi; Nahar Taufiq
Jurnal Teknosains Vol 9, No 1 (2019): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.51526

Abstract

Percutaneous Coronary Intervention (PCI) is an effective treatment for coronary artery diseases. For the procedure, a stent is put in the coronary arteries. There are a variety of stent materials and designs available on the market. The development of stents continues with the goal to reduce the risk of failure. The design and the ability of the stent as a vascular scaffold are important factors for the success of the stent. The implantation of a stent as a foreign body can lead to inflammation. In general, the inflammation is characterized by an increased number of lymphocytes. Then, platelets play a role in coordinating the occurrence of inflammation and immune response. This study aims to determine the effect of stent design on the number of lymphocytes and platelets as a marker of inflammation. The study was conducted on ten rabbits divided into two treatment groups, namely KP1 (new design stent) and KP2 (commercial stent) by placing a stent on the iliac artery. One hour before stenting, 2 ml of blood was collected in all experimental animals. Then, 2 ml of blood was collected again on the 7th and 28th day after stenting.  Data was collected based on the number of lymphocytes and platelets from all experimental animals. Statistical analysis using two-way ANOVA shows no significant difference (p> 0.05) on the number of lymphocytes and platelets between the two groups with different stent designs. It can be concluded that the design of a stent does not show a tendency to cause inflammation.
Hematologi rutin sapi peranakan ongole yang mengalami mumifikasi fetus Dinar Arifianto; Topas Wicaksono Priyo Jr; Erif Maha Nugraha Setyawan; Agus Purnomo; Dhirgo Adji; . Yuriadi
ARSHI Veterinary Letters Vol. 5 No. 1 (2021): ARSHI Veterinary Letters - Februari 2021
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.5.1.5-6

Abstract

Seekor sapi peranakan ongole dilaporkan melewati batas waktu perkiraan kelahiran pada bulan ke-10 tanpa menunjukkan adanya tanda-tanda mendekati kelahiran. Pemeriksaan ultrasonografi dilakukan untuk memastikan kondisi kebuntingan dan didapatkan gambaran dinding uterus bersinggungan dengan bentukan tulang dan teracak fetus serta cairan amnion yang sangat sedikit dan hampir mengering. Pemeriksaan fisik dan pengambilan sampel darah dilakukan untuk memperkuat diagnosis dan melakukan rencana terapi. Operasi caesar dilakukan untuk mengeluarkan fetus melalui prosedur operasi posisi berdiri pada flank kiri. Fetus berwarna coklat kekuningan dan mengalami perlekatan dengan kotiledon serta membran khorioalantois. Hasil gambaran darah sebelum operasi menunjukkan hasil nilai eritrosit, Hb, MCV, MCH, total leukosit, neutrofil, limfosit, monosit, eosinofil, total protein plasma (TPP), dan fibrinogen dalam batas normal. Trombosit dan MCHC mengalami penurunan sedangkan PCV mengalami peningkatan
Co-Authors . Yuriadi Agus Purnomo Christin Marganingsih Santosa Dhirgo Adji Dyah Anindya Widyasrini Erif Maha Nugraha Setyawan Nahar Taufiq Rosyadi, Imron Salasia Isrina Oktavia Siti Setyo Budhi Topas Wicaksono Priyo Jr Widowati Siswomihardjo