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All Journal Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Riset Ilmiah
Lukman Mahdi
Universitas Lambung Mangkurat
Humanities Economics, Econometrics & Finance Education Environmental Science Law, Crime, Criminology & Criminal Justice Public Health Social Sciences Other

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AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM FRAKSI AIR DAUN KRATOM (MITRAGYNA SPECIOSA) Lukman Mahdi
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 1 (2026): SINERGI : Jurnal Riset Ilmiah, January 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i1.2269

Abstract

Inadequate infection management poses a significant risk of complications, further exacerbated by biofilm-associated infections that lead to therapeutic failure and recurrence. Consequently, the development of novel antibacterial-antibiofilm agents is critical. Natural products offer substantial potential due to their diverse active compounds, notably Kratom leaves (Mitragyna speciosa), which have a long-standing history in traditional medicine. This study aims to evaluate the antibacterial and antibiofilm potential of the aqueous fraction of M. speciosa against Staphylococcus aureus and Escherichia coli. The methodology involved ethanol extraction of the leaf powder, followed by sequential fractionation to isolate the aqueous fraction. Antibacterial activity was assessed using the disk diffusion method, while antibiofilm efficacy was determined via the microbroth dilution method. Results indicated that aqueous fraction of M. speciosa inhibited the growth of S. aureus and E. coli, at concentrations of 5–25%. Antibiofilm assays revealed that the inhibitory effects of aqueous fraction of M. speciosa were dose-dependent. The aqueous fraction of M. speciosa at 1% concentration demonstrated effective inhibition across all three biofilm phases of S. aureus. Conversely, for E. coli, the maximum inhibitory effect was observed exclusively during the eradication phase. These findings confirm that the aqueous fraction of M. speciosa holds strategic potential for development as a natural antibacterial-antibiofilm agent.
Edukasi Perilaku Hidup Bersih dan Sehat serta Pengenalan Konsep Kefarmasian Pada Pelajar SDN Akar Bagantung Lukman Mahdi; Nashrul Wathan; Muhammad Ikhwan Rizki; Satrio Wibowo Rahmatullah; Novia Fahrina Purnama Sari; Hema Novita Rendati; Risa Susanti; Yuniarti Suryatinah; Nur Mahdi; Rina Astiyani Jennah; Dinna Fitria Kumala
Jurnal Pengabdian Kepada Masyarakat (MEDITEG) Vol. 11 No. 1 (2026): Jurnal Pengabdian Kepada Masyarakat (MEDITEG)
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat (P3M) Politeknik Negeri Tanah Laut (Politala)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/mediteg.v11i1.397

Abstract

Kesehatan menjadi fondasi penting bagi anak untuk merespons tantangan berbagai penyakit di era ini. Anak perlu distimulasi sedini mungkin untuk membangun karakter peduli kesehatan diri sendiri dan lingkungan. Meskipun saat ini informasi mudah diakses, kemampuan anak dalam menyaring informasi masih kurang sehingga perlu edukasi secara langsung. Kegiatan ini bertujuan untuk meningkatkan pemahaman pelajar SDN Akar Bagantung, Kabupaten Banjar, Kalimantan Selatan terkait perilaku hidup bersih dan sehat (PHBS) serta kefarmasian. Sebanyak 32 pelajar menjadi responden. Teknik edukasi menggunakan pembelajaran aktif yakni ceramah interaktif, video pembelajaran, dan simulasi. Tingkat pengetahuan siswa diukur menggunakan kuesioner sebelum (pretest) dan setelah pembelajaran (posttest). Hasil evaluasi menunjukkan sebanyak 68,75% siswa SDN Akar Bagantung menunjukkan peningkatan pengetahuan terkait PHBS dan kefarmasian. Nilai rata-rata gabungan pelajar setelah diberi edukasi adalah 95,31. Edukasi menggunakan pembelajaran aktif efektif dalam meningkatkan pengetahuan pelajar SDN Akar Bagantung mengenai perilaku hidup bersih dan sehat serta kefarmasian.
Co-Authors Dinna Fitria Kumala Hema Novita Rendati Muhammad Ikhwan Rizki Nashrul Wathan Novia Fahrina Purnama Sari Nur Mahdi Rahmatullah, Satrio Wibowo Rina Astiyani Jennah Risa Susanti Yuniarti Suryatinah