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Literature Review: Evaluation of Spesific and Non-Spesific Parameters in the Quality Assessment of Rhizome Simplicia Mars Jenita Grace Santy Indah Purba; Sofi Khoerunnisa; Dini Dwi Oktaviani; Caecilia Sukma Larasati; Yonathan Tri Atmodjo Reubun
Jurnal Ayurveda Medistra Vol 8 No 1 (2026): Jurnal Ayurveda Medistra: Jurnal Ilmiah Kesehatan
Publisher : STIKes Medistra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51690/medistra-jurnal123.v8i1.144

Abstract

Rhizomes are the underground stems of plants and are widely used as crude drug materials in the Indonesian traditional medicine industry because they contain various beneficial bioactive compounds. Rhizome crude drugs must meet quality standards that can be measured through two groups of parameters—specific and non-specific parameters—to ensure the safety, efficacy, and consistency of these raw materials. This study is a literature review that involves the collection and analysis of secondary data from ten scientific articles obtained through Google Scholar. This study focuses on the evaluation of specific parameters, namely organoleptic properties, water-soluble and ethanol-soluble extract content, as well as phytochemical profiles, and non-specific parameters such as drying loss, moisture content, total ash content, acid-insoluble ash content, and heavy metal content in ten types of rhizome crude drugs: red galangal, yellow turmeric, ginger, red ginger, kencur, purun danau, black temu, temu kunci, mango temu, and wundu watu. Analysis results indicate that Temu Kunci (Kaempferia pandurata Roxb.) has the best overall quality, followed by Red Ginger and Kencur, which each meet all established standards. Conversely, Black Temu and Mango Temu showed non-compliance with non-specific parameters, particularly regarding ash content and moisture content, indicating a need to improve post-harvest processing. Lake Purun requires special attention due to its high heavy metal content, which impacts the aquatic ecosystem in the lake. Standardizing both specific and non-specific parameters is a crucial step to ensure the quality and safety of rhizome crude drugs as raw materials for traditional medicine in Indonesia. Keywords: Herbal Rhizomes, Specific Parameters, Non-Specific Parameters
Formulasi dan Evaluasi Salep Virgin Coconut Oil (VCO) Lulu Hikmah Fauziah; Siti Haura Khairunnisa; Caecilia Sukma Larasati; Sofi Khoerunnisa; Dini Dwi Oktaviani; Feronika Evma Rahayu
Jurnal Ayurveda Medistra Vol 8 No 1 (2026): Jurnal Ayurveda Medistra: Jurnal Ilmiah Kesehatan
Publisher : STIKes Medistra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51690/medistra-jurnal123.v8i1.145

Abstract

An ointment is a semisolid formulation with a smooth texture, minimal water content, and hydrophobic properties; it is used for direct application to the skin or mucous membranes, including the eye area. Virgin Coconut Oil (VCO) is pure coconut oil processed without the use of chemicals or organic solvents; it has low water and free fatty acid content, is clear in appearance, has a distinctive aroma, and functions as a natural emollient and antioxidant. This study aims to formulate and evaluate sterile VCO-based ointments at various concentrations: 0% (F0), 10% (F1), 20% (F2), and 30% (F3). The ingredients used include VCO as the active ingredient (0–30%), liquid paraffin as an emollient (10%), lanolin as an emollient and emulsion stabilizer (5%), chlorobutanol as a preservative (0.5%), white petrolatum as the main base (85%), and triethanolamine (TEA) to adjust the pH (1%). Evaluation of the formulations involved analysis of general physical properties, acidity level, spreadability, adhesion, solution viscosity, and mixture uniformity. The findings showed that all formulations were white to off-white in color, semi-solid in form, had a characteristic odor, and a consistent texture. The pH value for F0 was 5 (acidic), while the pH for F1 through F3 was 7 (neutral). The spreadability of F0 through F2 was 5 cm, whereas F3 reached 7 cm. The adhesion time for F0 was 5 seconds, while F1 through F3 had an adhesion time of 4 seconds. Viscosity ranges from 25,600 to 43,100 mPa·s. All these parameters meet pharmaceutical standards, including a spreadability of 5 to 7 cm, a minimum adhesion time of 4 seconds, and a viscosity range of 2,000 to 50,000 mPa·s. Formula 2 (20% VCO) was identified as the best formula because it has a neutral pH, spreadability and adhesion that meet the criteria, a sufficiently high viscosity of 35,500 mPa·s, and a uniform texture. In conclusion, it can be concluded that the addition of terpene-rich coconut oil at a concentration of 20% produces a contamination-free ointment with the most balanced physical characteristics.