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Wastitiamurti, Ritsia Anindita
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Perbandingan Efektivitas Injeksi Agen-Agen Anti-Vegf pada Pengobatan Age-Related Macular Degeneration Nahak, Petronela Bhoko; Arsita, Elli; Wastitiamurti, Ritsia Anindita
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3143

Abstract

Age-related macular degeneration (AMD) is one of the leading causes of blindness in people >60 years of age in developed countries. The pathogenesis of neovascular AMD involves increased choroidal vascular permeability, leading to hypoxia and the production of pro-inflammatory and pro-angiogenic factors, particularly vascular endothelial growth factor (VEGF). Treatment of neovascular AMD involves anti-VEGF therapy, which inhibits abnormal blood vessel growth. Numerous studies have demonstrated the effectivity and side effects of each Anti-VEGF agent. Based on this background, the author is interested in conducting a literature review that summarizes the effectivity and side effects of each Anti-VEGF agent. The method used was Literature Review. Journals were collected using GoogleScholar or Google Scholar, PubMed and Proquest within the last 10 years. A total of 10 journals that met the inclusion-exclusion criteria were reviewed and tested for eligibility with the Ottawa score. The results of this literature review showed that anti-VEGF agents including bevacizumab, ranibizumab, aflibercept, pegaptanib sodium, brolucizumab and abicipar pegol have been shown to be equally effective in improving vision and maintaining stable vision in neovascular AMD patients. However, these anti-VEGF treatments can also cause side effects such as intraocular inflammation, increased intraocular pressure and vascular problems.
Gambaran Pengetahuan, Sikap, dan Perilaku Guru Mengenai kelainan Refraksi dan Astenopia pada Murid Sekolah Islam Terpadu INSANI Tahun 2025 Aulia, Tasya Noer; Wastitiamurti, Ritsia Anindita; Lesmana, Michael Indra
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3880

Abstract

The eye is the organ we use to see. Data from the Indonesian Ministry of Health, 15% of school-age children experience refractive disorders. According to the World Health Organization (WHO) report, the incidence of asthenopia globally is estimated to range from 75% to 90%. The purpose of the study was to determine the description of teachers' knowledge, attitudes, and behavior regarding refractive disorders and asthenopia in students of the INSANI Sukabumi Integrated Islamic School in 2025. Using a descriptive observational design with a cross-sectional approach, sampling using the total population method. The research sample consisted of 60 respondents. Data collection was carried out by filling out a questionnaire. The results showed that teachers who had good knowledge of refractive disorders were 28.3%, sufficient 48.3%, and lacking 23.3%. good attitude 93.3%, sufficient 6.4%. good behavior 50%, sufficient 21.7%, and lacking 28.3%. Teachers who have good knowledge about Astenopia 15%, sufficient 36.7%, lacking 48.3%. good attitude 98.3%, sufficient 1.7%. good behavior 41.7%, sufficient 15%, and lacking 43.3%. Increasing knowledge is an important step to support positive attitudes, so that they can be translated into consistent and appropriate behavior in supporting students' visual health in the school environment.
Co-Authors Aulia, Tasya Noer Elli Arsita Michael Indra Lesmana Nahak, Petronela Bhoko