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TINJAUAN ILMIAH MENGENAI PERBANDINGAN EFEKTIVITAS DAN KEAMANAN ERDOSTEIN, KARBOSISTEIN, DAN N-ASETILSISTEIN PADA PASIEN PENYAKIT PARU OBSTRUKTIF KRONIK EKSASERBASI AKUT Walter, Bryan; Wiliam, Wiliam; Citraningtyas, Theresia
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3145

Abstract

Acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) is a worsening of stable COPD/respiratory symptoms. The 2020 Global Initiative for Chronic Obstructive Lung Disease (GOLD) shows erdostein, carbocysteine, and n-acetylcysteine can reduce the risk of acute exacerbations in COPD. The aim of this writing is to determine and compare the effectiveness and safety of erdostein, carbocysteine, and n-acetylcysteine in acute exacerbations of COPD. The scientific review takes the form of a literature review by searching for data using books, journals and websites. Sixteen articles were obtained with the results that erdosteine, carbocysteine, and n-acetylcysteine reduced the risk of acute exacerbations of COPD. The best effectiveness results depend on the dose of the drug and the length of use. The best reduction in the risk of exacerbation was oral erdostein, dose 900 mg daily for 10 days (39.1%), Carbocysteine 1500 mg daily for 6-12 months (p < 0.00001) and n-acetylcysteine 1,200 mg/day for 3 months (p<0.05). Erdostein was well tolerated and there were no treatment-related side effects. The frequency of side effects of respiratory tract infections was not detected for erdostein, but for carbocysteine it was found to be 0.56% and NAC 10.85%. Two patients dropped out of the study because of gastrointestinal disturbances related to carbocysteine side effects. The conclusion of this scientific review is that the use of erdostein 900 mg/day for 10 days has the best effectiveness in reducing COPD exacerbations, then carbocysteine 1500 mg/day for 6-12 months, then n-acetylcysteine 1200 mg/day for 3 months.    
Kecemasan Preoperasi pada Pasien yang Akan Menjalani Operasi Appendiktomi: Kecemasan Preoperasi pada Pasien yang Akan Menjalani Operasi Appendiktomi Ramba, Erni; Tania, Elly; Citraningtyas, Theresia
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3351

Abstract

Anxiety is an individual's reaction to unexpected situations that everyone often experiences in life, providing warnings and directing someone to try to protect themselves. The process of surgery or surgery can cause anxiety reactions. This literature review aims to determine the description of anxiety in preoperative appendicitis patients and the factors that can influence the patient's preoperative anxiety level. Research articles in the form of clinical trials and randomized control trials were reviewed using the Google Scholar search engine, using specific keywords such as anxiety AND "preoperative" AND appendectomy AND comparison. A total of five relevant journals based on the purpose of the literature review. The conclusion from this literature review is that methods that can be implemented and are effective in reducing anxiety in pre-appendectomy patients include communication and education, implementation of the finger grip technique. Knowledge of surgical procedures can reduce anxiety. It should be noted in this literature review that the number of responses from each journal is still considered insufficient.
An Evaluation of BLU Hospital Efficiency: A Quantitative Approach with Data Envelopment Analysis Ebyude, Junius Chirsha; Denny, Denny; Winoto, Deddy Wahyu; Citraningtyas, Theresia
Indonesian Treasury Review: Jurnal Perbendaharaan, Keuangan Negara dan Kebijakan Publik Vol. 10 No. 1 (2025): Indonesian Treasury Review: Jurnal Perbendaharaan, Keuangan Negara dan Kebijak
Publisher : Direktorat Jenderal Perbendaharaan, Kementerian Keuangan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33105/itrev.v10i1.769

Abstract

Research Originality — This study is the first to assess the efficiency of Public Service Agency (BLU) hospitals in Indonesia using data envelopment analysis (DEA). It provides a comprehensive evaluation of hospital efficiency in multiple categories and identification of benchmark hospitals and areas for improvement. The study offers insights into hospital resource management efficiency to help policymakers in optimizing hospital performance. Research Objectives — This study aims to evaluate the efficiency of 32 BLU hospitals in Indonesia by analyzing their inpatient and outpatient services, human resource allocation, and bed utilization efficiency. It also investigates historical performance trends from 2016 to 2020 to assess long-term efficiency patterns. Research Methods — The study employed DEA, which is a non-parametric approach widely used for efficiency analysis. The evaluation was based on four input variables and seven output variables categorized into four main efficiency measures: inpatient services, outpatient services, human resources, and bed utilization. The efficiency scores were calculated using BCC-I and Super-Radial BCC-I models. Empirical Results — The findings showed that 15 hospitals were efficient, while 17 hospitals exhibited inefficiencies. Nine hospitals consistently demonstrated efficiency across all categories from 2016 to 2020, whereas four hospitals consistently underperformed in at least one category. The study also indicates that hospitals with lower efficiency scores can benchmark against efficient hospitals to improve performance. Implications — The findings of this study have policy implications for healthcare administrators and government agencies. The Directorate of BLU Financial Management Development can use the DEA results to guide hospital efficiency improvements. In addition, inefficient hospitals can use these findings to identify performance gaps and adopt best practices. Future studies could integrate other methods such as the Malmquist productivity index (MPI) or balanced scorecard (BSC) for a more comprehensive assessment.