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All Journal International Journal of Public Health Science (IJPHS) An Idea Health Journal
Benedicta Audrey Putri Trisnadewi
Universitas Karangturi
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Feasibility and Preliminary Effects of a Multimodal Non-Hormonal Intervention for Women With Early Menopause: A Mixed-Methods Study Ratih Kumala Dewi; Luluk Khusnul Dwihestie; Benedicta Audrey Putri Trisnadewi; Ratih Paramastuti; Emilia Boavida De Araujo
An Idea Health Journal Vol 6 No 03 (2026)
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/ihj.v6i03.730

Abstract

Background: Early menopause is characterized by hormonal decline, sleep disturbances, psychological distress, and diminished quality of life. Aim this study is developed and evaluated the feasibility and preliminary outcomes of an integrated intervention comprising phytoestrogen-based nutrition, Damask rose aromatherapy, and self-efficacy–based psychological support for women experiencing early menopause. Methods: An exploratory sequential mixed-methods design was implemented in Boyolali Regency, Central Java, Indonesia, from July to September 2025. The research process included needs assessment, intervention development, expert validation, pilot testing, and qualitative evaluation. Thirty-two women with early menopause participated in a four- week, one-group pretest–posttest intervention. Quantitative data were analyzed using paired t-tests or Wilcoxon signed-rank tests, and qualitative data were examined through inductive thematic analysis. The intervention was associated with improvements in several physiological and psychological outcomes. Result: Estradiol levels increased significantly (p = 0.021), HDL levels improved (p = 0.046), and fasting blood glucose decreased (p = 0.012). Significant improvements were also observed in sleep quality (p = 0.002), psychological distress (p < 0.05), menopause-related quality of life (p = 0.019), and menopause self-efficacy (p = 0.001). Conclusion: Qualitative findings demonstrated high acceptability of the intervention and identified perceived benefits, including relaxation, improved sleep, emotional adaptation, and increased confidence in managing menopausal symptoms. These pilot results indicate that an integrated intervention combining phytoestrogen-based nutrition, Damask rose aromatherapy, and self-efficacy–based psychological support is feasible and associated with improvements in hormonal, metabolic, sleep-related, and psychological outcomes among women with early menopause.
Multimodal non-hormonal intervention with phytoestrogen nutrition and Damask rose aromatherapy improves quality of life in early menopausal women: a quasi-experimental study Putri Dewi Anggraini; Ratih Kumala Dewi; Luluk Khusnul Dwihestie; Benedicta Audrey Putri Trisnadewi; Ratih Paramastuti
International Journal of Public Health Science (IJPHS) Vol 15, No 3: September 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i3.27078

Abstract

Early menopause and perimenopause are increasingly recognized as critical women’s health issues due to their substantial hormonal instability, heightened symptom burden, and negative impact on quality of life. Safe non-hormonal interventions remain limited, particularly in community settings, despite growing evidence supporting phytoestrogens and mind body therapies. This study aimed to evaluate the effectiveness of a 12-week holistic intervention integrating phytoestrogen nutrition, Damask rose aromatherapy, and guided relaxation on hormonal regulation, metabolic markers, menopausal symptoms, and quality of life among early menopausal and perimenopausal women. Using a quasi-experimental design, 44 participants received soy-based dietary supplementation, nightly aromatherapy, and structured relaxation practices, with pre-post assessments of estradiol, lipid profile, fasting glucose, Menopausal Rating Scale (MRS), and Menopause-Specific Quality of Life Questionnaire (MENQOL). The intervention produced significant improvements across all domains, including increased estradiol (p < 0.001), reduced low-density lipoprotein (LDL) and fasting glucose (p = 0.001-0.003), and substantial reductions in menopausal symptoms and psychological distress (p < 0.001). Early menopausal women exhibited greater improvements, reflecting their higher biological sensitivity to multimodal interventions. These findings demonstrate the potential of integrated, non-hormonal strategies to address complex menopausal changes, with practical implications for community-based women’s health programs. Study limitations include the modest sample size and quasi-experimental design, highlighting the need for larger controlled trials.
Co-Authors Emilia Boavida De Araujo Luluk Khusnul Dwihestie Putri Dewi Anggraini Ratih Kumala Dewi Ratih Kumala Dewi Ratih Paramastuti