Rahmadhani Tyas Angganawati
Sekolah Tinggi Ilmu Kesehatan Bogor Husada

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TELAAH FAKTOR YANG MEMPENGARUHI MEDICATION ERROR FASE DISPENSING PADA RESEP BPJS DI INSTALASI FARMASI RUMAH SAKIT PMI BOGOR PERIODE JULI-AGUSTUS 2024 Ghiesta Nurshaelawaty; Rahmadhani Tyas Angganawati; Rhamal Amir
Jurnal Kesehatan Sundaram Vol. 3 No. 2 (2026): JKS
Publisher : LPPM STIKes Buleleng

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52073/32ag4748

Abstract

Medication error merupakan kejadian yang dapat merugikan  pasien akibat adanya kesalahan pemakaian obat selama dalam penanganan tenaga kesehatan yang sebenarnya dapat dicegah. Penelitian ini bertujuan untuk mengidentifikasi bentuk dan persentase medication error serta menganalisis faktor yang paling berpengaruh pada fase dispensing di Instalasi Farmasi RS PMI Bogor sebagai bahan evaluasi serta meningkatkan pelayanan kefarmasian agar memenuhi standar pelayanan minimal tidak diperbolehkan adanya kesalahan terhadap pemberian obat-obatan. Jenis penelitian yang dilakukan merupakan penelitian analitik observasional. Pengambilan data dilakukan dengan metode cross sectional. Populasi adalah resep pasien, dengan jumlah sampel resep pasien rawat jalan  sebanyak 374 dengan 19 responden dan pada resep pasien rawat inap sebanyak 385 dengan 22 responden. Hasil penelitian menunjukkan bahwa terjadinya medication error fase dispensing di Instalasi Farmasi RS PMI Bogor ditemukan pada verifikasi akhir sebelum penyerahan sehingga obat yang diberikan ke pasien telah diperbaiki. Medication error pada fase dispensing resep rawat jalan terjadi pada pada kategori etiketnya salah, tertukar atau tidak lengkap sekitar 2,14%, kesalahan pengambilan jumlah obat 1,60%, kesalahan pengambilan obat (jenis, dan potensi) 0,53%, obat ada yang kurang (omission) 0,53%, salinan resep tidak lengkap atau tidak dibuatkan sebanyak 0,27%. Medication error pada fase dispensing resep rawat inap terjadi pada kategori kesalahan pengambilan jumlah obat 2,34%, etiketnya salah, tertukar atau tidak lengkap sekitar 1,82%, kesalahan pengambilan obat (jenis dan potensi) 0,52%. Analisis data menggunakan analisis regresi logistik. Hasil analisis yang paling berpengaruh terhadap medication error adalah variabel gangguan/interupsi bekerja dengan nilai signifikansi 0.002.
Analisis Drug Related Problems (DRPs) Penggunaan Nifedipin pada Pasien Hipertensi Gestasional di Instalasi Rawat Inap RSUD Y Periode 2024-2025 Lintang Tri Ananda; Rahmadhani Tyas Angganawati; Ilham Maulana
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2527

Abstract

This study aims to determine patterns of nifedipine use and analyze DRPs profiles based on the Pharmaceutical Care Network Europe (PCNE) among patients with gestational hypertension in the Inpatient Unit of Y Regional General Hospital during the 2024-2025 period. A retrospective descriptive study was conducted using the medical records of 60 patients who met the inclusion criteria. Therapeutic appropriateness was evaluated based on the 2017 National Medical Service Guidelines (PNPK) for the Management of Pregnancy Complications. The results showed that the majority were within the healthy reproductive age range of 20-35 years (61.7%), and the entire sample was in the third trimester (100%). The most common comorbid condition was anemia. Nifedipine use was dominated by a single 10 mg dose once daily (49%). A total of 28 DRPs were identified. The leading cause of DRPs was the drug selection domain (C1) in the subdomain of inappropriate drug combinations/drug interactions (C1.3), with 14 cases (50%), dominated by a pharmacosynergistic interaction between MgSO4 and nifedipine. In addition, there were 5 cases (18%) of excessively high doses (C3.2), 5 cases (18%) of too-frequent dosing regimens (C3.4), and 4 cases (14%) of too-short therapy duration (C4.1). Although nifedipine is the first-line choice, the incidence of DRPs remains quite high. Therefore, Medication Therapy Monitoring (MTM) and patient education are necessary to optimize clinical outcomes.
Identifikasi Drug Related Problem (DRPs) Kategori Ketepatan Obat, Kesesuaian Dosis, dan Interaksi Obat pada Pasien Diabetes Mellitus Tipe 2 dengan Komorbiditas Hipertensi di Rumah Sakit FMC Bogor Tahun 2024–2025 Tris Ella Julita Gulo; Rahmadhani Tyas Angganawati; Ilham Maulana
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2538

Abstract

This study aimed to analyze the incidence profile of DRPs in the categories of drug appropriateness, dose suitability, and drug interactions in type 2 diabetes patients with hypertension comorbidity at FMC Bogor Hospital in 2024–2025. This was a non-experimental study with a descriptive design and retrospective data collection using medical records. The sample consisted of 72 patients who met the inclusion criteria, selected through total sampling, and the data were analyzed descriptively. The results showed that DRPs in the drug appropriateness category were found in 7 patients (9.72%), comprising 6 patients who had an indication but did not receive therapy and 1 patient who experienced duplicate medication therapy. DRPs in the dose suitability category were found in 4 patients (5.55%), all of whom received antihypertensive medications below the therapeutic dose. Drug interactions were identified in 68 patients (94.44%), with moderate-level interactions being the most common severity, accounting for 201 cases (80.08%). Based on the mechanism, pharmacodynamic interactions were more dominant, with 190 cases (75.69%), compared with pharmacokinetic interactions at 61 cases (24.30%). These findings imply the need for closer monitoring of drug therapy to improve patient safety and treatment outcomes.